GLP1 News and Research

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From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

18 Dec 2023

How safe are GLP-1R agonists in early pregnancy?

JAMA Internal Medicine study examines the safety of GLP-1 receptor agonists and other second-line antidiabetic medications during early pregnancy, finding no significant increase in congenital anomalies compared to insulin use.

14 Dec 2023

New insights into how anti-obesity drugs could help prevent kidney disease

Data from Australian researchers could partly explain why a trial of a new drug for diabetes, was recently halted because it was found to be so effective.

8 Dec 2023

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

The study investigates the role of epigenetic changes in GLP1R gene polymorphisms on metabolically healthy obesity (MHO), revealing that apart from genetic variations, DNA methylation significantly influences the occurrence of MHO.

20 Nov 2023

How does the Mediterranean diet impact insulin resistance and sensitivity in obese individuals?

Researchers evaluate the associations between adherence to the Mediterranean diet, insulin secretion, resistance, and sensitivity in obese individuals.

30 Oct 2023

Experts to discuss if lasting remission from diabetes is feasible in real-world setting

At this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 Oct) experts will discuss if lasting remission from diabetes is feasible in the real-world setting.

4 Oct 2023

Could metformin be a game changer for heart health in non-diabetics?

Using Mendelian randomization, researchers found that altering seven metformin targets led to improved blood pressure and BMI in non-diabetic individuals. The study suggests the potential for metformin's role in reducing cardiovascular risks in the general population, although more research is needed.

24 Sep 2023

Research reveals racial and ethnic disparities in the benefits of newer type 2 diabetes drugs

New research analyzing the effects of two drugs used to treat type 2 diabetes indicates a consistent lack of cardiovascular and renal benefits in Black populations.

21 Sep 2023

Study finds semaglutide provides benefits for patients with obesity phenotype of heart failure and HFpEF

Researchers evaluated the efficacy of semaglutide in patients with the obesity phenotype of heart failure and preserved ejection fraction.

31 Aug 2023

Study: 93 million U.S. adults may benefit from semaglutide medication

Researchers from the University of California, Irvine have just published a study that projects 93 million U.S. adults that are overweight and obese may be suitable for the 2.4 mg dosage of semaglutide, a weight loss medication known under the brand name Wegovy.

16 Aug 2023

Revolutionizing type 2 diabetes treatment: personalized approach shows promise in matching patients with optimal glucose-lowering therapies

A personalized therapy selection algorithm for two diabetes type 2 (T2D) treatment drug classes.

10 Aug 2023

The microbiota connection, gut health linked to metabolic syndrome prevalence

The relationship between gut microbiota and metabolic disorders focused on BA metabolism and immunity.

1 Aug 2023

New heart cell atlas reveals detailed structure of the human heart

In a new study, published today (12 July) in Nature, researchers have produced the most detailed and comprehensive human Heart Cell Atlas to date, including the specialised tissue of the cardiac conduction system - where the heartbeat originates.

12 Jul 2023

Ever-growing global diabetes burden exacerbated by large-scale inequity

Despite increased awareness and ongoing multinational efforts, diabetes is pervasive, exponentially growing in prevalence, and outpacing most diseases globally, according to a new Series published in The Lancet and The Lancet Diabetes & Endocrinology journals.

5 Jul 2023

McMaster research opens new possibilities to help people maintain weight loss after dieting

Researchers led by McMaster University professor Gregory Steinberg and postdoctoral research fellow Dongdong Wang have uncovered a key mechanism for promoting weight loss and maintaining the burning of calories during dieting.

29 Jun 2023

A journey back to wellness after three kidney transplants and weight gain

Rowena Roque, 46, was having a problem that many people can relate to: doing everything in her power to lose weight and get healthy but never succeeding.

2 Mar 2023

Preventing, diagnosing, and treating cardiovascular disease in women

An article published in the journal Medical Clinics of North America provides recent updates on cardiovascular disease prevention, diagnosis, and treatment in women.

8 Feb 2023

Gut hormone receptor polyagonists show promise for obesity and diabetes

A new paper in the Journal of Clinical Investigation describes drugs that could help lose weight and manage type 2 diabetes mellitus (T2DM).

6 Feb 2023

Xanthan gum-based fluid thickener can lower blood glucose levels after eating, study shows

Type 2 diabetes mellitus is a common lifestyle disease that is prevalent worldwide. It can often lead to complications, such as diseases of the heart, and increased risk of death, but preventive measures, such as a healthy diet, can reduce these risks.

27 Dec 2022

Metformin reduces risk of severe COVID-19 in diabetic patients

A new study determines whether antidiabetic agents can reduce complications in COVID-19 patients with diabetes.

10 Oct 2022