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Deep learning method maps spatial architecture of brain cancer cells

Glioblastoma is the deadliest and most common type of malignant brain tumour in adults. One of the reasons it's almost always incurable is that individual tumour cells are very different from one another and shift dynamically between various 'states'.

4 Nov 2026

Researchers identify specific gene linked to female protection from autism

In many cases all it takes is one mutated gene to orchestrate changes across a whole network of genes linked to autism, according to new results published today in Nature by researchers at Boston Children's Hospital.

4 Nov 2026

Genetic variant tied to liver injury from blood pressure drugs

This new article publication from Acta Pharmaceutica Sinica B discusses the clinical features and genetic associations of rare liver injury caused by antihypertensive medications.

4 Nov 2026

Protein DUSP4 prevents immune cell exhaustion in colorectal cancer

The immune system has powerful cells that can recognize and destroy cancer, but this ability can gradually wane when the cells reside within a tumor.

4 Nov 2026

Disrupting three Salmonella genes weakens bacterial biofilm defenses

A major challenge to combating bacterial infections is the formation of biofilms-protective structures that allow bacteria to adhere to surfaces and reproduce, increasing their chances of survival even when challenged with antibiotics and the host's immune system.

4 Nov 2026

A three-drug diabetes pill outperformed dual therapy

Clinical trial results indicate that a fixed-dose combination of dapagliflozin, glimepiride, and metformin offers superior glycemic control in diabetes therapy.

4 Nov 2026

Genetic family mapping uncovers hidden links across ALS and FTD

Researchers at the Macquarie University Brain Institute and Clinic have helped accelerate the search for disease-causing genes by building new genetic 'families'.

3 Nov 2026

AlphaFold3 reveals molecular interactions driving T cell recognition

Researchers at the Translational Genomics Research Institute (TGen), part of City of Hope, have developed a new approach using the artificial intelligence platform AlphaFold3 to predict whether a T cell receptor will recognize a specific antigen based solely on its genetic sequence.

3 Nov 2026

Synthetic DNA molecules enable precise targeting of cancer-linked genes

Researchers have developed a promising new approach that uses synthetic DNA molecules to target cancer-linked genes directly, opening new possibilities for future treatments, diagnostics and biological research.

3 Nov 2026

DHA improves autism-like behaviors in a preclinical rat study

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition marked by social and communication difficulties and repetitive behaviors.

3 Nov 2026

Spaceflight research opens new avenues for studying rare pediatric diseases

Earth-based hiPSC models have transformed disease research but remain limited by cellular immaturity, a strong reliance on glycolysis rather than oxidative phosphorylation (OXPHOS), and incomplete tissue architecture.

3 Nov 2026

Study identifies new target to improve ulcerative colitis treatments

Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease in which persistent mucosal inflammation damages the epithelial barrier.

3 Nov 2026

Alliance for Clinical Trials in Oncology highlights key role of clinical research in advancing men's cancer care

Every November, millions worldwide grow mustaches and join Movember, a global movement launched in 2003 to spark conversations about men's health, including prostate cancer, testicular cancer, and mental health.

3 Nov 2026

New study identifies biological mechanism driving therapy resistance in advanced prostate cancer

A multi-institutional collaborative study led by researchers at the University of Chicago and the Fred Hutchinson Cancer Center has identified a previously unknown biological mechanism that controls cell identity and treatment resistance in advanced prostate cancer.

3 Nov 2026

Tumor mutations may help predict relapse risk in childhood leukemia

Some cases of the most common childhood cancer, B-cell acute lymphoblastic leukemia (B-ALL), return after treatment - and genetic changes present from the start may help explain why.

2 Nov 2026

Gene therapy successfully corrects genetic defect in alpha-1 antitrypsin deficiency

In a landmark achievement in the field of genetic medicine, researchers have reported the very first published case in a peer-reviewed journal of a successful clinical treatment of a patient with alpha-1 antitrypsin deficiency (PiZZ) using in vivo gene therapy.

2 Nov 2026

Scientists may have underestimated how much genes contribute to Alzheimer's risk

A large multi-ancestry genetic analysis identified 127 genomic loci associated with Alzheimer's disease, including 48 previously unreported loci, and implicated microglial and neuronal gene-expression patterns in disease susceptibility. The researchers estimated that common genetic variants account for 16% of Alzheimer's disease liability in European-ancestry populations, substantially higher than previous estimates, while demonstrating improved polygenic risk prediction that remained less reliable in non-European populations.

2 Nov 2026