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Investigational oral therapy shows safety and potential benefits in ALS trial

In a phase 2b clinical trial, an investigational oral therapy called PrimeC was found to be safe and well tolerated in people living with amyotrophic lateral sclerosis (ALS), with exploratory findings suggesting target engagement and potential clinical benefits.

16 Mar 2026

New BrainGate iBCI typing neuroprosthesis can restore communication in patients with paralysis

Loss of communication can be among the most devastating symptoms for patients with paralysis. A new study by investigators from Mass General Brigham Neuroscience Institute and Brown University describes an investigational implantable brain computer interface (iBCI) typing neuroprosthesis that can restore communication with speed and accuracy.

16 Mar 2026

New polygenic risk scores improve prediction of metabolic disease outcomes

Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features.

16 Mar 2026

Using machine learning to identify individuals at risk for intimate partner violence

Researchers at Mass General Brigham have developed a series of artificial intelligence (AI) tools that uses machine learning to identify individuals who may be at risk for intimate partner violence (IPV) using information from their electronic medical records (EMRs).

13 Mar 2026

Romiplostim prevents chemotherapy-induced thrombocytopenia in phase 3 trial

Results from a global phase 3 clinical trial led by investigators at Mass General Brigham show that the medication romiplostim can effectively prevent chemotherapy from destroying platelet-producing bone marrow cells, a common complication known as chemotherapy-induced thrombocytopenia.

12 Mar 2026

High-dose vitamin D3 does not reduce COVID-19 severity, but may impact long COVID outcomes

In a large, randomized trial, researchers at Mass General Brigham have found that high-dose vitamin D3 did not reduce COVID-19 infection severity, but may impact long COVID outcomes.

12 Mar 2026

High medical debt leads to significant delays in routine and preventive care

Medical debt is associated with deferred dental care, medical care, and mental health care, even among people with health insurance, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

11 Mar 2026

Daily multivitamin intake linked to slower biological aging in older adults

An analysis led by Mass General Brigham investigators found slower aging in older adults after two years of a daily multivitamin, with greater benefits for those who began the trial with accelerated biological age.

9 Mar 2026

Trump’s cuts to Medicaid threaten services that help disabled people live at home

Leisa and Kent Walker recently received a disturbing notice: The private company managing their son's Medicaid coverage intends to cut nearly 40% of what it spends for caregivers who help him live at home instead of in a nursing home.

5 Mar 2026

As ICE moved in, Minnesotans set up a shadow medical system. It’s a lesson for other cities.

Gabi has big brown eyes, pigtails, and a genetic condition that makes her bones brittle. They fracture easily, leaving the 2-year-old in such pain that her mother quit her job cleaning offices to stay home and cradle her in the one-bedroom apartment they share with six relatives.

5 Mar 2026

Families defend disability services amid Medicaid cuts

Families of Idahoans with disabilities say their lives could be upended as lawmakers in the state's Republican-dominated legislature mull sweeping cuts.

2 Mar 2026

ChatGPT Health fails critical emergency and suicide safety tests

ChatGPT Health, a widely used consumer artificial intelligence (AI) tool that provides health guidance directly to the public-including advice about how urgently to seek medical care-may fail to direct users appropriately to emergency care in a significant number of serious cases, according to researchers at the Icahn School of Medicine at Mount Sinai.

24 Feb 2026

Sex differences in coronary plaque burden and cardiovascular event risk revealed

Coronary artery disease (CAD) is the most common cause of death globally. In CAD, plaques composed of cholesterol, fats, calcium and other compounds accumulate and create obstructions in the coronary vessels that supply blood to the heart.

23 Feb 2026

Stereotactic radiation improves quality of life in patients with brain metastases

In a Phase 3 randomized trial, Mass General Brigham researchers found that stereotactic radiation targeting individual tumors led to lower symptom burden, better cognitive outcomes, and better day to day function when compared with whole brain radiation

19 Feb 2026

Low-field MRI could offer an alternative to existing breast cancer screening methods

Mass General Brigham's evaluation of low-field MRI performance lays potential groundwork for this technology to be a lower-cost, accessible option for breast imaging.

19 Feb 2026

Survey reveals rising workload pressures on nurses

Nurses are increasingly overloaded. This is especially true in nursing homes and in home care, as shown by the results of the latest nursing survey.

13 Feb 2026

Brain circuit links past experiences to appetite control

Our past experiences shape how much we eat and where and what we choose to eat. Using preclinical models, researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have identified brain cells that translate contextual information into appetite control.

12 Feb 2026

Addiction consults improve care for drug-related eye infections

Eric Gaier, MD, PhD, and Dean Eliott, MD, of the Department of Ophthalmology at Mass Eye and Ear, a member of the Mass General Brigham healthcare system, are co-authors of a paper published in Ophthalmology Retina, "Substance Use Disorder Interventions and Ophthalmic Outcomes for Injection Drug Use-Associated Endogenous Endophthalmitis."

10 Feb 2026

AI foundation model advances comprehensive brain MRI analysis

Mass General Brigham investigators have developed a robust new artificial intelligence (AI) foundation model that is capable of analyzing brain MRI datasets to perform numerous medical tasks, including identifying brain age, predicting dementia risk, detecting brain tumor mutations and predicting brain cancer survival.

5 Feb 2026

Wake-promoting drug improves alertness in early morning shift workers

Many more people work very early morning shifts than overnight ones, and a large proportion struggle with excessive sleepiness from shift work disorder, leading to problems with focus, performance and safety.

29 Jan 2026

Home Care News and Research

Investigational oral therapy shows safety and potential benefits in ALS trial

New BrainGate iBCI typing neuroprosthesis can restore communication in patients with paralysis

New polygenic risk scores improve prediction of metabolic disease outcomes

Using machine learning to identify individuals at risk for intimate partner violence

Romiplostim prevents chemotherapy-induced thrombocytopenia in phase 3 trial

High-dose vitamin D3 does not reduce COVID-19 severity, but may impact long COVID outcomes

High medical debt leads to significant delays in routine and preventive care

Daily multivitamin intake linked to slower biological aging in older adults

Trump’s cuts to Medicaid threaten services that help disabled people live at home

As ICE moved in, Minnesotans set up a shadow medical system. It’s a lesson for other cities.

Families defend disability services amid Medicaid cuts

ChatGPT Health fails critical emergency and suicide safety tests

Sex differences in coronary plaque burden and cardiovascular event risk revealed

Stereotactic radiation improves quality of life in patients with brain metastases

Low-field MRI could offer an alternative to existing breast cancer screening methods

Survey reveals rising workload pressures on nurses

Brain circuit links past experiences to appetite control

Addiction consults improve care for drug-related eye infections

AI foundation model advances comprehensive brain MRI analysis

Wake-promoting drug improves alertness in early morning shift workers

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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