Hutchinson Gilford Progeria News and Research

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Blocking Hutchinson-Gilford progeria syndrome (HGPS) with anticancer drugs

A class of anticancer drugs currently being evaluated in phase 3 clinical trials may also be an effective treatment for Hutchinson-Gilford progeria syndrome (HGPS), a fatal genetic disorder that causes premature aging.

29 Aug 2005

Drugs known as farnesyltransferase inhibitors (FTIs) may hold promise for premature aging disorder

In a surprising development, a research team led by the National Human Genome Research Institute (NHGRI), has found that a class of experimental anti-cancer drugs also shows promise in laboratory studies for treating a fatal genetic disorder that causes premature aging.

29 Aug 2005

Adiponectin may be helpful in finding treatments for Progeria

In a study published in the March issue of The Journal of Pediatrics, researchers found that decreased levels of HDL cholesterol, or "good" cholesterol, may contribute to premature heart disease in children with Hutchinson-Gilford Progeria Syndrome, or Progeria.

8 Mar 2005

Gene mutation gradually causes devastating effects on cellular structure and function in Hutchinson-Gilford progeria syndrome

A mutation of the gene for lamin A protein gradually causes devastating effects on cellular structure and function in Hutchinson-Gilford progeria syndrome

29 Jun 2004