Low Density Lipoproteins (LDL) News and Research

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Upsher-Smith Laboratories publishes results of SLIM Study

Results of the SLIM Study ("Slo-Niacin® and Atorvastatin Treatment of Lipoproteins and Inflammatory Markers in Combined Hyperlipidemia") were recently published in the Journal of Clinical Lipidology.

17 Nov 2009

Upsher-Smith Laboratories publishes data on Slo-Niacin and Lipitor combination study

28 Oct 2009

Liraglutide drug causes less nausea and hypoglycaemia compared to exenatide

New data on patient treatment satisfaction from the LEAD(TM) 6 trial presented on the 22nd October at the 20th World Diabetes Congress (International Diabetes Federation) shows that patients have higher overall treatment satisfaction with liraglutide than they do with exenatide.

23 Oct 2009

94-year-old crusader seeks ban on trans fats in the American diet

Fred Kummerow, a 94-year-old University of Illinois veterinary biosciences professor emeritus who still conducts research on the health effects of trans fats in the diet, filed the petition with the FDA last month. The petition is now posted on the FDA Web site, and public comments are invited. (See below for information on viewing the petition and making a comment.)

4 Sep 2009

New understanding on how "trans fats" gum up cellular machinery

Partially hydrogenated vegetable oils in processed foods contain trans fatty acids that interfere with the regulation of blood flow. A new report reveals a new way in which these "trans fats" gum up the cellular machinery that keeps blood moving through arteries and veins.

17 Jun 2009

Issues on cholesterol: diet, statins and genetics

Genetic lipoprotein disorders are frequently seen in patients with premature coronary artery disease (CAD). An example of strong genetic predisposition is the disorder: familial hypercholesterolemia, where a single gene defect (the low density lipoprotein receptor) contributes to most of the familial expression of CAD.

1 Sep 2008

Discovery of potential target for elevated triglycerides

Diabetes researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC have identified a potential target for the development of new therapies to treat hypertriglyceridemia, a lipid disorder commonly seen in people who are obese and diabetic. Results of their study are published in the June issue of the Journal of Clinical Investigation.

26 May 2008

Researchers uncover key interaction in cholesterol regulation

Researchers at UT Southwestern Medical Center have determined the specific way in which a destructive protein binds to and interferes with a molecule that removes low-density lipoproteins (LDL), the so-called "bad" cholesterol, from the blood.

4 Feb 2008

Supplements of lipoic acid could reduce atherosclerosis, weight gain

A new study done with mice has discovered that supplements of lipoic acid can inhibit formation of arterial lesions, lower triglycerides, and reduce blood vessel inflammation and weight gain - all key issues for addressing cardiovascular disease.

15 Jan 2008

Older women more knowledgeable about cholesterol than younger women

Older adult American women are better informed about cholesterol and more likely to monitor it than younger adult women, but gaps remain in cholesterol knowledge and efforts to screen for it adequately, according to results of a national survey released by the Society for Women's Health Research, a Washington, D.C., based advocacy organization.

21 Sep 2007

Mechanism for the in-vivo transport of siRNA

It all started with flowers: in the nineties of the last century Norwegian researchers discovered that additional copies of a particular gene in petunias inhibited its activity instead of reinforcing it as had been assumed.

18 Sep 2007

New patented method for transporting medicine across the blood-brain barrier

Researchers at the Blanchette Rockefeller Neurosciences Institute have patented a new way of safely transporting medicine across the blood-brain barrier.

24 May 2007

Synthetic molecule helps detect heart attack in the making

A new bright spot in heart disease research may soon allow physicians to peer directly into patients' blood vessels and find dangerous cholesterol-filled plaques before they rupture and cause a heart attack.

2 Apr 2007

Medications plus lifestyle changes work as well as angioplasty to reduce deaths in stable heart-disease patients

Coronary revascularization with stenting or balloon angioplasty combined with optimal medical therapy is no more effective in preventing a heart attack, other major cardiovascular events or death in patients with stable heart disease, than optimal medical therapy alone, results of a new study conducted in 50 hospitals in the U.S. and Canada has shown.

27 Mar 2007

Benefits of breast-feeding might outweigh risk of vertical HIV transmission in developing countries

A series of studies presented Monday at the 14th Annual Conference on Retroviruses and Opportunistic Infections in Los Angeles suggest that the benefits of breast-feeding in developing countries might outweigh the risk of vertical HIV transmission, the San Francisco Chronicle reports.

28 Feb 2007

Tubby tummies in kids increase the risk of serious disease later on

A new study by American researchers has found that between 1988 and 2004 abdominal obesity increased more than 65 percent among boys and almost 70 percent among girls.

7 Nov 2006

Genetic clues to longevity

In a new study, Drs. Gil Atzmon and Nir Barzilai at the Albert Einstein College of Medicine of Yeshiva University have found that people harbor alleles--alternative forms of a gene--that confer the same sort of longevity advantage.

4 Apr 2006

Protein that regulates cholesterol levels may lead to new drug targets in the fight against obesity

A protein that regulates cholesterol levels in the body also is responsible for maintaining a healthy balance between fat storage and fat burning, according to a UT Southwestern Medical Center study that may lead to new drug targets in the fight against obesity.

12 Apr 2005

Questions about validity of HOPE TOO vitamin E study

A study published in the March 16 issue of Journal of the American Medical Association (JAMA) suggesting that a "daily-dose" of vitamin E (400 international units) among high-risk (chronically ill) cardiovascular patient populations is associated with a greater risk of heart failure is being challenged by leading health researchers around the country who claim the study lacks the adequate research and controlled sampling audience to justify this conclusion.

16 Mar 2005

Lipid profile differences explain why two people with the same overall cholesterol level can have different degrees of cardiovascular disease

When it comes to lipid profiles -- a key measure of heart disease risk-- it appears that African-Americans and women have it better than whites and men, according to a new study by Duke University Medical Center researchers.

7 Oct 2004