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Study sheds new light on the mechanisms underlying head and neck cancer metastasis

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC). The research identified enolase 2 (ENO2), a crucial glycolytic enzyme, as a significant factor associated with lymphatic metastasis in HNSCC.

27 Mar 2025

Understanding the role of LSD1 in cellular processes and disease

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases.

8 Mar 2025

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

3 Mar 2025

Lactylation in the heart reveals key insights into cardiac regeneration

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

28 Feb 2025

Plant immune responses may offer insights into human brain diseases

A groundbreaking study led by a team of researchers at the University of Kentucky's Martin-Gatton College of Agriculture, Food and Environment has revealed a surprising biochemical connection between plant immune responses and human neurological health.

19 Feb 2025

Short-chain fatty acids propionate and butyrate directly modify chromatin to regulate gene expression

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer and normal cellular processes.

13 Jan 2025

Histone markers predict human age with accuracy comparable to DNA methylation clocks

Researchers unveil histone-based age predictors, offering a new window into epigenetic aging and its shared patterns across tissues.

2 Jan 2025

Setd2 catalytic activity is crucial for embryonic development in mice

A recent study delves into the pivotal role of Setd2, a histone methyltransferase enzyme, in embryonic development within mice.

27 Dec 2024

Long-term green tea catechins prevent aging-related cardiac dysfunction

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101284, discusses the effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I.

20 Dec 2024

A new era of targeted therapy with antibody–drug conjugates

TBC

From Sino Biological Inc. 16 Dec 2024

New research sheds light on how monkeys avoid hepatitis B infection

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids.

4 Dec 2024

RNA enzyme found key to heart cell energy shift after birth

Researchers investigate the influence of Mettl1 on energy metabolism and the maturation of heart cells after birth.

29 Nov 2024

Research sheds light on Salmonella’s ability to escape gut defenses

A new UC Davis Health study has uncovered how Salmonella bacteria, a major cause of food poisoning, can invade the gut even when protective bacteria are present.

15 Nov 2024

Early bedtime boosts children's gut health by increasing beneficial bacteria

Study reveals that children who go to bed early have a more diverse and healthier gut microbiome compared to late sleepers, suggesting a link between sleep habits and gut health. It also highlights key metabolic pathways that differ between early and late sleepers.

8 Oct 2024

Innovative HiTIP-seq method advances epigenetic research in pediatric brain tumors

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal cord.

24 Sep 2024

Distinct gut bacteria identified in octogenarians linked to aging and health

Research reveals unique gut bacteria in Singaporean seniors, highlighting the microbiome's role in promoting healthier aging and reducing chronic disorders.

11 Sep 2024

Austocystin D's anticancer efficacy linked to CYP2J2 enzyme activity

Austocystin D, a natural compound produced by fungi, has been recognized for its cytotoxic effects and anticancer activity in various cell types. It exhibits potent activity even in cells that express proteins associated with multidrug resistance, attracting significant global research interest.

27 Aug 2024

Exploring the health benefits and production challenges of alternative proteins

Researchers review the health benefits of alternative protein sources and the challenges associated with their production.

20 Aug 2024

Higher heme iron intake linked to increased risk of type 2 diabetes

Higher intake of heme iron, the type found in red meat and other animal products - as opposed to non-heme iron, found mostly in plant-based foods - was associated with a higher risk of developing type 2 diabetes (T2D) in a new study led by researchers at Harvard T.H. Chan School of Public Health.

13 Aug 2024

New histone tag discovery offers hope for myelin repair in neurodegenerative diseases

In a groundbreaking study, researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have identified a distinct histone tag in adult oligodendrocyte progenitor cells (OPCs) that may pave the way for innovative therapies targeting myelin repair, a critical target for several neurodegenerative and psychiatric disorders, including multiple sclerosis, Alzheimer's disease, and schizophrenia.

12 Aug 2024