Melanoma Cells News and Research

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A drug for heart conditions improves efficacy of melanoma therapies

A collaborative study undertaken by the Navarrabiomed Biomedical Research Center (Pamplona, Navarre), the Institute of Neurosciences CSIC-UMH (Sant Joan d'Alacant, Valencian Community) and IRB Barcelona (Barcelona, Catalonia) shows that the administration of ranolazine, a drug currently used to treat heart conditions, improves the efficacy of current therapies for melanoma, in mouse models of this disease.

10 Aug 2023

GABA transfer between skin cells promotes melanoma initiation

The transfer of a neurotransmitter from one type of skin cell to another (melanocytes to keratinocytes) altered electrical activity and promoted melanoma initiation in preclinical models, according to results published in Cancer Discovery, a journal of the American Association for Cancer Research.

9 Aug 2023

Novel noninvasive test for malaria does not require a blood sample

A novel testing platform under development by researchers at the Yale School of Public Health (YSPH) and CytoAstra, LLC could provide a new noninvasive test for malaria that doesn't require a blood sample.

28 Jul 2023

New protein found to help melanoma evade the immune system

New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease.

5 Jul 2023

Manipulating white blood cells to eliminate solid tumors

By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors.

12 Jun 2023

New class of immunotherapy shows promise against aggressive skin cancer

A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.

25 Apr 2023

Experimental mRNA vaccine plus an immunotherapy reduced the likelihood of melanoma recurrence

The combination of an experimental mRNA vaccine with an immunotherapy reduced the likelihood of melanoma recurring or causing death by 44% when compared to immunotherapy alone, a new clinical trial shows.

17 Apr 2023

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

Researchers reviewed the importance of the circadian rhythm in the formation and progression of tumors.

29 Mar 2023

CD9-positive exosomes inhibit the growth of malignant melanoma, study suggests

Malignant melanoma is a relatively aggressive type of skin cancer. When detected early, it is usually treatable by surgical resection only, but metastases develop often spreading to distant areas.

28 Mar 2023

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.

3 Mar 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Dietary plant sugar promotes antitumor immunity and enhances the efficacy of immunotherapy

Immunotherapies have improved outcomes of many patients with cancer, including melanoma. But these therapies work for only a subset of patients.

23 Jan 2023

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

In this interview, News-Medical spoke to Dr. Jeremy Carlton and Professor Victoria Sanz-Moreno about their latest research into the spread of skin cancer.

20 Jan 2023

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Researchers discovered that the elevated expression of LAP1, an inner nuclear membrane protein, helps metastatic melanoma cells surmount the physical challenges presented by tissue structure and the microenvironment during metastasis.

11 Jan 2023

Researchers discover the Nrf3-mediated mechanism of melanogenesis

The skin is presumably the largest and one of the most versatile body organs. By providing a physical barrier, it protects our body from environmental assaults.

11 Jan 2023

Researchers discover a protein that makes melanoma more aggressive

Research led by Queen Mary University of London, King's College London and the Francis Crick Institute has identified a protein that makes melanoma, the most serious type of skin cancer, more aggressive by giving cancer cells the ability to change the shape of their nucleus – a characteristic which allows the cells to migrate and spread around the body.

9 Jan 2023