Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Study identifies a novel direct drug target for head and neck squamous cell carcinoma

Chemotherapy remains a cornerstone of treatment for head and neck cancers, the seventh-most common cancer type worldwide.

6 Aug 2026

Nerve-tumor interactions emerge as a transformative frontier in oncology

A new review article highlights a rapidly emerging frontier in oncology: the dynamic and influential relationship between nerves and tumors.

6 Aug 2026

Hidden microbes inside tumors reshape cancer immunity and treatment

A growing body of evidence is reshaping how cancer is understood, placing the spotlight on intra-tumoral microbiota as powerful yet previously overlooked players within the tumor microenvironment.

6 Aug 2026

Blocking ZFP36L2 protein may disrupt colorectal cancer metastatic growth

Digestion is hard on the cells that line the human gut, and they are constantly being shed and replaced. This renewal is driven by a population of tireless stem cells.

5 Aug 2026

HMGCR emerges as a promising target for precision cancer therapies

A growing body of evidence is reshaping how scientists and clinicians understand the role of cancer metabolism, placing the enzyme HMGCR at the center of a rapidly evolving therapeutic landscape.

5 Aug 2026

Tumor-secreted protein makes lung blood vessels leaky to promote metastasis

A protein secreted by common cancer types makes blood vessels leakier to allow metastatic tumors to form in the lungs, according to a study led by investigators at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center.

5 Aug 2026

Versatile receptor protein plays critical role in regulating tissue repair

A comprehensive new review highlights the expanding importance of Lgr6, a member of the G protein-coupled receptor family, as a critical regulator of tissue homeostasis, injury repair, and disease development across multiple organ systems.

5 Aug 2026

Cancer cells exploit liver fat to evade immune system destruction

Liver metastases are among the most common and deadly forms of cancer spread. Now, researchers at VIB and KU Leuven, with international collaborators, have discovered how cancer cells exploit a fatty acid abundant in the liver to evade destruction by the immune system.

5 Aug 2026

NIH funds research to explore the role of thymulin in inflammaging and cancer

As we age, chronic inflammation-or "inflammaging"-increases throughout the body and weakens our ability to fight cancer.

4 Aug 2026

Study links dietary fructose to aggressive spread of ovarian cancer

A new study from The Wistar Institute has uncovered an unexpected link between fructose - a common dietary sugar - and the spread of an aggressive form of ovarian cancer.

30 Jul 2026

Plant-based diets reshape gut microbes to boost healthy metabolites

Plant-based diets are good for you. They promote gut, immune, metabolic and cardiovascular health, in part by cultivating a diverse community of intestinal bacteria.

27 Jul 2026

New blood test improves colorectal cancer recurrence risk prediction

A single preoperative blood sample may help improve the prediction of recurrence or metastasis in patients with colorectal cancer.

21 Jul 2026

Specialized blood vessels enable effective immune defense against cancer metastases

It has long been suspected that endothelial cells, the specialized cells lining the inner walls of blood vessels, play a key role in determining how the body’s immune system responds to tumors.

20 Jul 2026

New target makes cancer cells vulnerable to immune destruction

Researchers at the University of Illinois Chicago have identified a molecular switch that helps determine whether cancer cells remain soft and difficult to destroy or become stiff enough for the immune system to attack.

20 Jul 2026

Specialized dendritic cells found to coordinate antitumor immunity

Researchers at the Icahn School of Medicine at Mount Sinai have identified the immune cell that acts as the architect and coordinator of powerful immune hubs that form inside tumors and plays a key role in antitumor immunity.

16 Jul 2026

Single-cell analysis identifies key regulators of cancer metastasis

By analyzing individual cancer cells, researchers from the Université Libre de Bruxelles (ULB) discovered the transcriptional regulators governing EMT in tumors and identified key master regulators that control metastasis, unraveling novel therapeutic vulnerabilities to block metastatic dissemination.

16 Jul 2026

Weill Cornell Medicine receives DoD grant to target triple-negative breast cancer

Weill Cornell Medicine has received a $2.5 million, three-year grant from the Department of Defense (DoD) to develop therapies with fewer side effects for triple-negative breast cancer, one of the most aggressive and difficult-to-treat breast cancers.

16 Jul 2026

Bile acid buildup linked to aggressive breast cancer progression

A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of the body, new University of Virginia Comprehensive Cancer Center research reveals.

15 Jul 2026

Integrating gene signatures and multi omics improves liver cancer treatment

Hepatocellular carcinoma (HCC) remains highly fatal due to late diagnosis and scarce early biomarkers.

14 Jul 2026

New genomic map identifies hundreds of genes governing bone health

In a global breakthrough published in Nature Genetics, researchers have successfully mapped the cells and genes that regulate bone formation and loss at an unprecedented scale and discovered the critical role that blood vessel cells play in bone health.

10 Jul 2026