Neglected Tropical Disease News and Research

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Illustrations by Nigerian artist kickstart debate on neglected tropical disease

Illustrations by a local artist in Nigeria are helping health workers and policy makers understand what it's really like to live with a neglected tropical disease (NTD).

5 Nov 2020

PATH wins grant to develop oral treatment option for soil-transmitted helminth infections

PATH announced today they received a grant from Japan's Global Health Innovative Technology Fund to develop a new oral treatment option for soil-transmitted helminth infections.

1 Oct 2020

Scientists to use CRISPR gene-editing technology for Phase 1 vaccine trials in humans

Scientists are planning for Phase 1 human trials of a vaccine they developed by using CRISPR gene-editing technology to mutate the parasite that causes leishmaniasis, a skin disease common in tropical regions of the world and gaining ground in the United States

25 Sep 2020

Study uncovers how schistosome worms trick the host's immune system

Researchers uncovered in a new study how schistosomes, parasitic flatworms that infect more than 200 million people in the tropics, trick the host's immune system and continue producing eggs for decades.

3 Aug 2020

New chemical could potentially lead to a cure for neglected tropical diseases

Scientists say they are a step closer to developing a drug to kill the trypanosome parasite that causes human African trypanosomiasis, otherwise known as sleeping sickness, paving the way for a potential cure.

13 Jul 2020

JGU professor wins Exploration Grant for research into membrane proteins of parasites

So-called neglected tropical diseases (NTDs) cause great suffering in some of the world's poorest countries and can lead also to significant economic losses due to, for example, the infestation of animal herds.

4 Jun 2020

Showers, toilets and washbasins may act as SARS-CoV-2 reservoirs despite low environmental transmission

In their new research paper currently available on the medRxiv* preprint server, scientists from the University of Bonn in Germany demonstrated that indirect environmental transmission most likely plays only a minor role in the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, certain potentially neglected viral reservoirs have to be taken into account when introducing epidemiological measures.

3 Jun 2020

Venatorx and GARDP collaborate to accelerate development of new antibiotic

Venatorx Pharmaceuticals and the Global Antibiotic Research and Development Partnership (GARDP) today announced a collaboration to accelerate the development of, and access to, cefepime-taniborbactam (formerly cefepime/VNRX-5133).

29 Apr 2020

Global funding for neglected disease research reaches a record high

For the first time, global funding for neglected disease R&D grew for three consecutive years, reaching a record high of more than US$4.05 billion in 2018.

30 Jan 2020

Intellegens and Optibrium announce success in the Open Source Malaria global initiative

Intellegens, an artificial intelligence start-up, and, Optibrium, leading providers of software and services for drug discovery, today announced joint success in the Open Source Malaria global initiative aimed at identifying the best predictive models for antimalarial compounds.

6 Dec 2019

Using genomics to identify promising novel treatment for lymphatic filariasis

Using innovative RNA sequencing techniques, researchers at the University of Maryland School of Medicine Institute for Genome Sciences identified a promising novel treatment for lymphatic filariasis, a disabling parasitic disease that is difficult to treat.

3 Dec 2019

International consortium to receive BRL 43.5 million for discovering drugs to treat neglected diseases

In the search for new drugs to treat neglected diseases and malaria, researchers at the University of Campinas and University of Sao Paulo will assemble a team of scientists in a global collaboration network co-funded by the São Paulo Research Foundation, the Drugs for Neglected Diseases initiative and the Medicines for Malaria Venture.

26 Nov 2019

Otago researchers join vaccine research project to tackle Salmonella bloodstream infections in Africa

A team of University of Otago researchers is part of a major new international vaccine research project to help tackle devastating Salmonella bloodstream infections which are killing thousands of people in sub-Saharan Africa each year.

1 Nov 2019

Research could open a promising new path to control schistosomiasis

Scientists have isolated a natural chemical that acts as a potent kryptonite against parasitic worms that burrow through human skin and cause devastating health problems.

From PLOS ONE 18 Oct 2019

Research could lead to new ways to fight against schistosomiasis

Scientists at the Morgridge Institute for Research have isolated a natural chemical that acts as a potent kryptonite against schistosomes, the parasitic worms that burrow through human skin and cause devastating health problems.

17 Oct 2019

New leishmaniasis look-alike parasitic infection reported

A new study published online in the journal Emerging Infectious Diseases describes the appearance of a new protozoan infection carried by insects which causes symptoms that mimic the disease called visceral leishmaniasis, caused by a different parasite.

2 Oct 2019

Study: Transmission of protozoan parasite may cause leishmaniasis-like symptoms in people

A new study published this week online in Emerging Infectious Diseases suggests that transmission of a protozoan parasite from insects may also cause leishmaniasis-like symptoms in people

1 Oct 2019

Molecular changes are linked with adverse events following treatment of lymphatic filariasis

The Global Program to Eliminate Lymphatic Filariasis delivers mass drug administration to 500 million people each year, and adverse events are common following treatment. Now, researchers have reported in PLOS Neglected Tropical Diseases that certain changes in gene expression are associated with these adverse events.

From PLOS ONE 25 Sep 2019

Alzheimer’s drug an interesting candidate for the treatment of parasitic Chagas disease

Researchers have discovered that an Alzheimer's drug could serve as a starting point in treating Chagas disease.

20 Sep 2019

Johns Hopkins researchers estimate real-world prevalence of prurigo nodularis

Johns Hopkins researchers report that prurigo nodularis, a skin disease characterized by severely itchy, firm bumps on the skin, may be associated with other inflammatory skin disorders as well as systemic and mental health disorders.

From Johns Hopkins Medicine 26 Aug 2019