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Study evaluates effectiveness of deep brain stimulation for treatment-resistant schizophrenia patients

Winner of the Best International Abstract Award, Laura Salgado Lopez, MD, presented her research, A Pilot Study of Deep Brain Stimulation in Treatment-resistant Schizophrenia, during the 2017 American Association of Neurological Surgeons Annual Scientific Meeting.

25 Apr 2017

Research findings shed light on brain’s ability to make split-second decisions

When animals hunt or forage for food, they must constantly weigh whether the chance of a meal is worth the risk of being spotted by a predator. The same conflict between cost and benefit is at the heart of many of the decisions humans make on a daily basis.

25 Apr 2017

Synchronized voltage rhythms in SCN could play role in maintaining the body’s circadian clock

Cells in the brain's master circadian clock synchronize voltage rhythms despite asynchronous calcium rhythms, which might explain how a tissue-wide rhythm is maintained.

24 Apr 2017

RCSI researchers discover that function of KCNQ1 gene is linked to survival of colon cancer patients

Researchers from RCSI (Royal College of Surgeons in Ireland) and the University of Nice, France, have discovered the function of a gene called KCNQ1 that is directly related to the survival of colon cancer patients.

21 Apr 2017

Researchers show how dengue virus employs multiple tactics to evade immune detection

For the human body to mount an immune response to a viral infection, host cells must identify the viral invader and trigger a signaling pathway. This signal then prompts the immune system to attack and subdue the pathogen.

19 Apr 2017

Researchers discover molecular compound that targets nucleus of allergen-sensitized cells

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions.

18 Apr 2017

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Researchers at Fred Hutchinson Cancer Research Center have developed biodegradable nanoparticles that can be used to genetically program immune cells to recognize and destroy cancer cells -- while the immune cells are still inside the body.

17 Apr 2017

Seeing genes inside living cells

For Mazhar Adli, the little glowing dots dancing about on the computer screen are nothing less than the fulfillment of a dream. Those fluorescent dots, moving in real time, are set to illuminate our understanding of the human genome, cancer and other genetic diseases in a way never before possible.

14 Apr 2017

Scientists discover new role for autophagosomes in neurodegenerative diseases

Autophagosomes are at the center of attention, at least since the Nobel Prize for Medicine was awarded for research on autophagy in 2016. The much talked about autophagosomes are small membrane vesicles in charge of waste disposal to promote recycling of its components.

11 Apr 2017

New research sheds light on movement of white blood cells to sites of infection

One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other barriers.

10 Apr 2017

BrainDx develops new measurement tool for precise diagnosis of ADHD and autism

Software company BrainDx (http://braindx.net/) announces a pioneering measurement tool to assist practitioners and researchers in differentiating between ADHD and autism spectrum disorder (ASD) in children.

7 Apr 2017

Researchers provide new insights into age-related female infertility

Researchers at the University of Montreal Hospital Research Center have discovered a possible new explanation for female infertility.

4 Apr 2017

Researchers shed light on genome reorganization after fertilization in single-cell mammalian embryo

Using a newly developed method researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences have been able to shed light on the complexity of genome reorganization occurring during the first hours after fertilization in the single-cell mammalian embryo

30 Mar 2017

Study shows how epigenetic randomness helps cancer cells proliferate

In a research effort that merged genetics, physics and information theory, a team at the schools of medicine and engineering at The Johns Hopkins University has added significantly to evidence that large regions of the human genome have built-in variability in reversible epigenetic modifications made to their DNA.

27 Mar 2017

Researchers develop new way to assemble genome of an organism from scratch

A team spanning Baylor College of Medicine, Rice University, Texas Children's Hospital and the Broad Institute of MIT and Harvard has developed a new way to sequence genomes, which can assemble the genome of an organism, entirely from scratch, dramatically cheaper and faster.

24 Mar 2017

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Consumption of the synthetic drug MDPV -a powerful psychostimulant known as 'cannibal drug'- in adolescence, can increase vulnerability of cocaine addiction during adulthood, according to a study carried out with laboratory animals and led by the researchers Elena Escubedo, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the UB and Olga Valverde, head of the Neurobiology of Behaviour Research Group of Pompeu Fabra University.

22 Mar 2017

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Researchers at Baylor College of Medicine, Texas Children's Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals.

22 Mar 2017

High-resolution images of protein complex performing first step in genome-replication dance captured

It's a good thing we don't have to think about putting all the necessary pieces in place when one of our trillions of cells needs to duplicate its DNA and then divide to produce identical daughter cells.

17 Mar 2017

Study shows how socially contagious itching is hardwired in the brain

Some behaviors — yawning and scratching, for example — are socially contagious, meaning if one person does it, others are likely to follow suit. Now, researchers at Washington University School of Medicine in St. Louis have found that socially contagious itching is hardwired in the brain.

10 Mar 2017

Researchers develop optimized sensors to study biochemical underpinnings of learning and memory

Learning and memory are crucial aspects of everyday life. When we learn, our neurons use chemical and molecular signals to change their shapes and strengthen connections between neurons, a process known as synaptic plasticity.

9 Mar 2017