Cell Nucleus News and Research

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Researchers discover molecular compound that targets nucleus of allergen-sensitized cells

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions.

18 Apr 2017

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Researchers at Fred Hutchinson Cancer Research Center have developed biodegradable nanoparticles that can be used to genetically program immune cells to recognize and destroy cancer cells -- while the immune cells are still inside the body.

17 Apr 2017

Seeing genes inside living cells

For Mazhar Adli, the little glowing dots dancing about on the computer screen are nothing less than the fulfillment of a dream. Those fluorescent dots, moving in real time, are set to illuminate our understanding of the human genome, cancer and other genetic diseases in a way never before possible.

14 Apr 2017

Scientists discover new role for autophagosomes in neurodegenerative diseases

Autophagosomes are at the center of attention, at least since the Nobel Prize for Medicine was awarded for research on autophagy in 2016. The much talked about autophagosomes are small membrane vesicles in charge of waste disposal to promote recycling of its components.

11 Apr 2017

New research sheds light on movement of white blood cells to sites of infection

One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other barriers.

10 Apr 2017

BrainDx develops new measurement tool for precise diagnosis of ADHD and autism

Software company BrainDx (http://braindx.net/) announces a pioneering measurement tool to assist practitioners and researchers in differentiating between ADHD and autism spectrum disorder (ASD) in children.

7 Apr 2017

Researchers provide new insights into age-related female infertility

Researchers at the University of Montreal Hospital Research Center have discovered a possible new explanation for female infertility.

4 Apr 2017

Researchers shed light on genome reorganization after fertilization in single-cell mammalian embryo

Using a newly developed method researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences have been able to shed light on the complexity of genome reorganization occurring during the first hours after fertilization in the single-cell mammalian embryo

30 Mar 2017

Study shows how epigenetic randomness helps cancer cells proliferate

In a research effort that merged genetics, physics and information theory, a team at the schools of medicine and engineering at The Johns Hopkins University has added significantly to evidence that large regions of the human genome have built-in variability in reversible epigenetic modifications made to their DNA.

27 Mar 2017

Researchers develop new way to assemble genome of an organism from scratch

A team spanning Baylor College of Medicine, Rice University, Texas Children's Hospital and the Broad Institute of MIT and Harvard has developed a new way to sequence genomes, which can assemble the genome of an organism, entirely from scratch, dramatically cheaper and faster.

24 Mar 2017

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Consumption of the synthetic drug MDPV -a powerful psychostimulant known as 'cannibal drug'- in adolescence, can increase vulnerability of cocaine addiction during adulthood, according to a study carried out with laboratory animals and led by the researchers Elena Escubedo, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the UB and Olga Valverde, head of the Neurobiology of Behaviour Research Group of Pompeu Fabra University.

22 Mar 2017

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Researchers at Baylor College of Medicine, Texas Children's Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals.

22 Mar 2017

High-resolution images of protein complex performing first step in genome-replication dance captured

It's a good thing we don't have to think about putting all the necessary pieces in place when one of our trillions of cells needs to duplicate its DNA and then divide to produce identical daughter cells.

17 Mar 2017

Study shows how socially contagious itching is hardwired in the brain

Some behaviors — yawning and scratching, for example — are socially contagious, meaning if one person does it, others are likely to follow suit. Now, researchers at Washington University School of Medicine in St. Louis have found that socially contagious itching is hardwired in the brain.

10 Mar 2017

Researchers develop optimized sensors to study biochemical underpinnings of learning and memory

Learning and memory are crucial aspects of everyday life. When we learn, our neurons use chemical and molecular signals to change their shapes and strengthen connections between neurons, a process known as synaptic plasticity.

9 Mar 2017

Penn researchers identify genome-wide changes caused by high-fat diet

By comparing two strains of mice -- one that becomes obese and diabetic on a high-fat diet and another resistant to a high-fat regimen -- researchers from the Perelman School of Medicine at the University of Pennsylvania identified genome-wide changes caused by a high-fat diet.

8 Mar 2017

Study reveals promising new strategy to attack deadly pediatric brain tumor

Researchers from Northwestern Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago have revealed new insight into how the most deadly pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG), may develop.

7 Mar 2017

Researchers test 'three-hit' theory of autism in mice

Since the first case was documented in the United States in 1938, the causes of autism have remained elusive. Hundreds of genes, as well as environmental exposures, have been implicated in these brain disorders.

7 Mar 2017

Researchers reveal how overloading of protein transport mechanisms triggers cellular defects

Researchers at Okayama University report in Scientific Reports how the overloading of protein transport mechanisms affects cell functioning. Over-expression of different types of target proteins leads to cellular growth defects, and the mechanism for transporting proteins out of a cell nucleus has the lowest over-expression tolerance.

7 Mar 2017

Scientists discover how misfolded proteins can damage cells’ energy-producing powerhouses

Working with yeast and human cells, researchers at Johns Hopkins say they have discovered an unexpected route for cells to eliminate protein clumps that may sometimes be the molecular equivalent of throwing too much or the wrong trash into the garbage disposal.

3 Mar 2017

Cell Nucleus News and Research

Researchers discover molecular compound that targets nucleus of allergen-sensitized cells

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Seeing genes inside living cells

Scientists discover new role for autophagosomes in neurodegenerative diseases

New research sheds light on movement of white blood cells to sites of infection

BrainDx develops new measurement tool for precise diagnosis of ADHD and autism

Researchers provide new insights into age-related female infertility

Researchers shed light on genome reorganization after fertilization in single-cell mammalian embryo

Study shows how epigenetic randomness helps cancer cells proliferate

Researchers develop new way to assemble genome of an organism from scratch

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Researchers uncover gene mutation that may provide answers to unexplained female infertility

High-resolution images of protein complex performing first step in genome-replication dance captured

Study shows how socially contagious itching is hardwired in the brain

Researchers develop optimized sensors to study biochemical underpinnings of learning and memory

Penn researchers identify genome-wide changes caused by high-fat diet

Study reveals promising new strategy to attack deadly pediatric brain tumor

Researchers test 'three-hit' theory of autism in mice

Researchers reveal how overloading of protein transport mechanisms triggers cellular defects

Scientists discover how misfolded proteins can damage cells’ energy-producing powerhouses

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