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Enzyme appears to be a major driver of dangerous pregnancy complication

A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine.

9 Sep 2021

Combating the fourth wave of COVID-19 in Ontario

Researchers from Canada recently attempted to project the number of COVID-19 cases and the demand for acute hospital resources for Fall 2021 in a mid-sized southwestern Ontario community. They sought to evaluate if current vaccine coverage and contact reduction levels are sufficient to mitigate a possible 4th wave driven by the Delta variant, or if stricter public health measures need to be reinstituted.

8 Sep 2021

New suggestions emphasize the importance of contingency level care during COVID-19 pandemic

The journal CHEST recently published an important update to the 2014 consensus statement by the Task Force for Mass Critical Care (TFMCC) on providing mass critical care utilizing research gained through experiencing the 2020 COVID-19 pandemic.

8 Sep 2021

Study reveals better outcomes for patients treated on a mobile stroke unit

Ischemic stroke patients treated on a mobile stroke unit received anti-clot medication faster and ended up with less disability at 90 days, according to a study published today in the New England Journal of Medicine led by researchers at The University of Texas Health Science Center at Houston and Memorial Hermann-Texas Medical Center.

8 Sep 2021

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Despite cigarette smoking being the single most preventable risk factor for both chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), two devastating diseases that make it hard to breathe, about 44 million American adults continue to smoke.

8 Sep 2021

Hotter weather associated with worsening of COPD symptoms

Warmer weather is linked to a worsening of chronic obstructive pulmonary disease (COPD) symptoms, according to research to be presented on Sunday at the 'virtual' European Respiratory Society International Congress.

3 Sep 2021

Losing weight and treating excess fat levels may help prevent lung disease in 9/11 firefighters

Losing weight and treating excess levels of fat in the blood may help prevent lung disease in firefighters who were exposed to dangerous levels of fine particles from fire, smoke, and toxic chemicals on September 11, 2001, a new study shows.

2 Sep 2021

Growing use of mechanical circulatory support causes moral distress among clinicians

The growing use of mechanical circulatory support (MCS) may contribute to high levels of moral distress for clinicians who regularly care for critically ill patients receiving the aggressive but life-sustaining therapy, according to a study in American Journal of Critical Care.

1 Sep 2021

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Octapharma USA today announced the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has awarded seven years of marketing exclusivity for Octagam® 10% [Immune Globulin Intravenous (Human)], the first and only intravenous immunoglobulin (IVIg) to be indicated for the treatment of adult dermatomyositis (DM).

31 Aug 2021

Rescue breathing CPR for pediatric cardiac arrest has superior outcomes, analysis shows

Rescue breathing cardiopulmonary resuscitation (CPR) had superior neurological outcomes compared with compression-only CPR or no CPR at all in infants, children and adolescents, according to a new analysis published today in the Journal of the American College of Cardiology.

30 Aug 2021

Stiffening of heart’s blood vessels associated with lack of enzyme that fosters cell ‘chatter’

In a study in mice, Johns Hopkins Medicine researchers have found that the smooth muscle cells lining the walls of blood vessels can lose their elasticity and lead to vascular stiffening, a condition that can precede heart disease and stroke.

26 Aug 2021

Researchers identify numerous genetic regions that may affect individuals' food intake

A team of researchers at Massachusetts General Hospital, Boston University School of Public Health, and other institutions have identified more than two dozen genetic regions that may affect individuals' food intake.

25 Aug 2021

UC San Diego Health performed region’s first double lung transplant for a COVID-19 patient

On a July afternoon, Federico Gomez Gil, 56, is dressed in a short-sleeved, collared shirt, sweatpants and a baseball cap. He sits in a chair in a hospital room, surrounded by his wife and two daughters. Given the past five months, this is the moment of a lifetime — a new lifetime.

24 Aug 2021

Major UK study redefines care for critically ill children on ventilation

A major UK clinical trial led by Queen’s University Belfast has shown how a new approach to reduce the use of mechanical ventilation can greatly improve outcomes for critically ill infants and children.

24 Aug 2021

Newly developed CPAP System provides a cost-effective respiratory device for COVID patients

In an attempt to make breathing devices available to low-income areas, scientists have developed the LeVe CPAP System for respiratory support to treat COVID.

24 Aug 2021

Study suggests a novel therapeutic target to reverse lung fibrosis

Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, or IPF, as reported in a study published in the journal Cell Death and Differentiation.

24 Aug 2021

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

A six country clinical study of more than 1,100 hospitalized COVID-19 patients who required high-flow nasal cannula oxygen therapy suggests that prone positioning (rotating patients with severe breathing issues so they are face down) soon after admission can significantly reduce the need for mechanical ventilation.

23 Aug 2021

Research finds potential overuse of antibiotics in patients with severe SARS-CoV-2 pneumonia

Only 21 percent of patients with severe pneumonia caused by SARS-CoV-2 (the virus that causes COVID-19) have a documented bacterial superinfection at the time of intubation, resulting in potential overuse of antibiotics, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

20 Aug 2021

Vaccine quickly reduced COVID-19 infections among health care workers

A UC Davis Health retrospective study published recently in Infection Control and Hospital Epidemiology shows how quickly COVID-19 infections were reduced among health care workers when vaccines were first distributed late last year.

19 Aug 2021

Emergency Department sees a significant increase in COVID-19 cases during August 2021

The Emergency Department (ED) at UC Davis Medical Center saw a 33% increase in COVID-19 patients during the first week of August, providing treatment for 107 patients, up from 80 patients the week before.

13 Aug 2021

Critical Care News and Research

Enzyme appears to be a major driver of dangerous pregnancy complication

Combating the fourth wave of COVID-19 in Ontario

New suggestions emphasize the importance of contingency level care during COVID-19 pandemic

Study reveals better outcomes for patients treated on a mobile stroke unit

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Hotter weather associated with worsening of COPD symptoms

Losing weight and treating excess fat levels may help prevent lung disease in 9/11 firefighters

Growing use of mechanical circulatory support causes moral distress among clinicians

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Rescue breathing CPR for pediatric cardiac arrest has superior outcomes, analysis shows

Stiffening of heart’s blood vessels associated with lack of enzyme that fosters cell ‘chatter’

Researchers identify numerous genetic regions that may affect individuals' food intake

UC San Diego Health performed region’s first double lung transplant for a COVID-19 patient

Major UK study redefines care for critically ill children on ventilation

Newly developed CPAP System provides a cost-effective respiratory device for COVID patients

Study suggests a novel therapeutic target to reverse lung fibrosis

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

Research finds potential overuse of antibiotics in patients with severe SARS-CoV-2 pneumonia

Vaccine quickly reduced COVID-19 infections among health care workers

Emergency Department sees a significant increase in COVID-19 cases during August 2021

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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