Genetic Engineering News and Research

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Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

New trial tests combination antibody treatment for preventing COVID-19 illness

A combination antibody treatment for preventing COVID-19 illness in individuals who have had sustained exposure to someone with the virus is being studied by researchers at The University of Texas Health Science Center at Houston.

25 Sep 2020

New optical switch to precisely control the lifespan of genetic 'copies'

A novel optical switch makes it possible to precisely control the lifespan of genetic "copies". These are used by the cell as building instructions for the production of proteins.

25 Sep 2020

New device helps study the reaction of individual cells to mechanical stress

The behavior of cells is controlled by their environment. Besides biological factors or chemical substances, physical forces such as pressure or tension are also involved.

25 Sep 2020

Alzheimer’s disease-associated protective genetic variant enhances key functions of immune cells

A new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer's disease, enhances several key functions of immune cells. The results obtained in the study highlight the importance of immune cells as a target of future development of new therapies for Alzheimer's disease.

25 Sep 2020

NeutrobodyPlex nanobodies help monitor SARS-CoV-2 immune responses

Researchers recently described a set of 11 Nbs derived from an immunized alpaca which showed high-affinity binding to the glycosylated SARS-CoV-2 spike receptor domain (RBD) in a study published in the preprint server bioRxiv.

23 Sep 2020

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Researchers from Critical Analytics for Manufacturing Personalized-Medicine, an interdisciplinary research group at Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have been awarded Intra-CREATE grants from the National Research Foundation Singapore to help support research on retinal biometrics for glaucoma progression and neural cell implantation therapy for spinal cord injuries.

22 Sep 2020

Gene therapy used to overcome the cardiac effects of Freidreich’s ataxia

Gene therapy was successfully used to overcome the cardiac effects of Freidreich’s ataxia (FA) in a mouse model of the disease, as reported in the peer-reviewed journal Human Gene Therapy. Click here to read the full-text article free online through October 18, 2020.

19 Sep 2020

Research provides deeper understanding of how neurons in the nose react to odors

Take a sniff of a freshly poured glass of wine, and the prevailing scientific thinking would suggest that the harmony of fragrances you perceive starts with sensory receptors in your nose simply adding up the individual odors they encounter.

19 Sep 2020

ERS Genomics and Applied StemCell sign agreement on commercialization of CRISPR gene editing tools

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property (IP) co-owned by Dr. Emmanuelle Charpentier, today announced it has signed an agreement with Applied StemCell, Inc., a leading provider of stem cell, animal model, antibody discovery services and reagents.

17 Sep 2020

3D cluster of cells could enhance myocardial repair

Cell therapy for cardiac regeneration, while promising, has been hampered by issues with long-term survival of the transplanted cells.

15 Sep 2020

SMART researchers discover a new way to manufacture human red blood cells

Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have discovered a new way to manufacture human red blood cells (RBCs) that cuts the culture time by half compared to existing methods and uses novel sorting and purification methods that are faster, more precise and less costly.

14 Sep 2020

UMSOM researchers determine role of protein in development of hearing hair cells

Researchers at the University of Maryland School of Medicine have conducted a study that has determined the role that a critical protein plays in the development of hair cells.

12 Sep 2020

Study highlights the importance of considering strain differences when designing therapies

Interferon (IFN) responses are one of the first defenses the body mounts against viral infections, and research has shown that it plays a role controlling viral replication.

11 Sep 2020

Novel discovery could lead to stem cell-based treatment for heart failure

Blocking an enzyme linked with inflammation makes it possible for stem cells to repair damaged heart tissue, new research from UC Davis Health scientists shows.

10 Sep 2020

Scientists shed new light on gene regulatory pathways activated by stress hormone

Scientists have long known that chronic stress experienced early in life, or even chronic prenatal exposure to maternal stress hormones in the womb, can shorten lifespan and contribute to age-related chronic diseases like arthritis, asthma, cancer, cardiovascular disease, diabetes and even mental illness later in life -- long after the source of stress has been removed.

9 Sep 2020

AAV gene therapy often leads to dorsal root ganglion pathology, show studies

A meta-analysis of non-human primate (NHP) studies showed that adeno-associated virus (AAV) gene therapy often caused dorsal root ganglion (DRG) pathology.

3 Sep 2020

Study: BIRC2 overexpression could be a key marker for immunotherapy resistance

Johns Hopkins Medicine researchers have added to evidence that a gene responsible for turning off a cell's natural "suicide" signals may also be the culprit in making breast cancer and melanoma cells resistant to therapies that use the immune system to fight cancer.

2 Sep 2020

FEFU scientists to design genetically modified models for understanding malignant gliomas

Scientists of Far Eastern Federal University get started studying the formation and survival mechanisms of the brain malignant tumors cells, i.e. glioma, to reveal new ways for diagnosis and therapy for this fatal disease.

31 Aug 2020

Two discoveries can lead to a new wave of more-complex organoid development

In back-to-back reports published Aug. 27, 2020, in Nature Communications, a team of scientists from Cincinnati Children's and Japan report discoveries that will be vital to a new wave of more-complex organoid development.

27 Aug 2020

Genetic Engineering News and Research

Researchers decipher how the immune system memorizes pathogens after an infection

New trial tests combination antibody treatment for preventing COVID-19 illness

New optical switch to precisely control the lifespan of genetic 'copies'

New device helps study the reaction of individual cells to mechanical stress

Alzheimer’s disease-associated protective genetic variant enhances key functions of immune cells

NeutrobodyPlex nanobodies help monitor SARS-CoV-2 immune responses

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Gene therapy used to overcome the cardiac effects of Freidreich’s ataxia

Research provides deeper understanding of how neurons in the nose react to odors

ERS Genomics and Applied StemCell sign agreement on commercialization of CRISPR gene editing tools

3D cluster of cells could enhance myocardial repair

SMART researchers discover a new way to manufacture human red blood cells

UMSOM researchers determine role of protein in development of hearing hair cells

Study highlights the importance of considering strain differences when designing therapies

Novel discovery could lead to stem cell-based treatment for heart failure

Scientists shed new light on gene regulatory pathways activated by stress hormone

AAV gene therapy often leads to dorsal root ganglion pathology, show studies

Study: BIRC2 overexpression could be a key marker for immunotherapy resistance

FEFU scientists to design genetically modified models for understanding malignant gliomas

Two discoveries can lead to a new wave of more-complex organoid development

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