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Studies explore bioactive compounds in plants for disease prevention

Fruits and plant extracts contain bioactive compounds that can help treat or prevent diseases. To characterize and understand their mechanism of action, researchers from universities and research institutions in Brazil and Germany have conducted independent but complementary studies.

28 Mar 2025

New research reveals factors influencing steroid hormone levels in healthy adults

Steroid hormone levels in healthy adults are influenced by oral contraceptives and smoking, as well as other lifestyle choices and factors such as biological sex and age, according to new research that has just been published in leading international journal Science Advances.

28 Mar 2025

New insights into how the immune system handles latent parasite infections

Most humans have long-lived infections in various tissues-including in the nervous system-that typically do not result in disease.

28 Mar 2025

Lipid accumulation in tumors linked to therapy resistance in breast cancer

A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop resistance to therapy.

28 Mar 2025

Harnessing intestinal microbes to combat inflammation and infections

Despite being an everyday necessity, nutrition is something of a black box. We know that many plant-based foods are good for us, but we don't always know why.

27 Mar 2025

Novel insights into tumor microenvironment and gastric cancer therapy

A team of Singapore scientists has made a significant discovery in understanding stomach cancer, a disease that remains one of the deadliest cancers worldwide. By using advanced mapping technologies, they created a detailed "atlas" of stomach tumors, revealing hidden patterns in how cancer cells behave, evolve and interact with their environment. These insights could lead to more precise, targeted treatments that improve survival rates and reduce side effects.

27 Mar 2025

COVID-derived molecular mimics may be involved in triggering autoimmunity

COVID infection has been linked to higher risk of autoimmune disorders, including rheumatoid arthritis and type 1 diabetes.

26 Mar 2025

Microneedles accelerate diabetic wound healing in preclinical models

Diabetic wounds often lead to severe complications that can result in amputations. These chronic and non-healing wounds are marked by persistent inflammation, affecting more than six per cent of the global population.

26 Mar 2025

Report shows alarming measles resurgence in Europe and US

A recent report shows cases of measles across the World Health Organization's European Region, which includes the UK, are the highest they've been for more than 25 years. At the same time, large outbreaks of measles in the US have led to the first measles deaths there since 2015.

26 Mar 2025

Study reveals distinct infection strategies of Zika and dengue viruses

Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host's dendritic cells.

25 Mar 2025

Yale study unlocks potential of lupus-related antibody to target cold tumors

Yale scientists have discovered a promising way to trigger immune responses against certain tumors, using a lupus-related antibody that can slip, undetected, into "cold" tumors and flip on an immune response that has been turned off by cancer.

25 Mar 2025

Scientists develop universal vaccine targeting multiple coronaviruses

Sugar coatings aren't only for candies; they also help viruses, like the ones that cause COVID-19, hide from their hosts' immune system.

25 Mar 2025

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Researchers develop tool to enhance NK cells against cancer

A team of researchers from the Hospital del Mar Research Institute, the Universitat Autònoma de Barcelona and the Pompeu Fabra University has developed a new tool that allows modifying these NK cells to make them immune to the tumor’s defense mechanism.

24 Mar 2025

Nanotechnology innovation aims to improve breast cancer treatment

University of Queensland researchers are designing nanotechnology they believe could improve how we treat the most aggressive form of breast cancer.

24 Mar 2025

New monoclonal antibody shows promise in treating mucormycosis

Mucormycosis, a fungal infection caused by Mucorales, has high mortality rates in people with weakened immune systems and those suffering from severe trauma like burns, blast injuries or victims of natural disasters.

22 Mar 2025

Bacteria use dormant phages to create immunity against viral invaders

Like people, bacteria get invaded by viruses. In bacteria, the viral invaders are called bacteriophages, derived from the Greek word for bacteria-eaters, or in shortened form, "phages."

22 Mar 2025

Scientists decode differentiation pathways of human blood stem cells

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

21 Mar 2025

Pitt researchers develop a new way to profile pediatric brain tumors

Researchers and pediatric neurosurgeons at the University of Pittsburgh School of Medicine and UPMC Children's Hospital of Pittsburgh developed a new way to profile brain cancers in children, paving the way for improved diagnostics and treatments.

19 Mar 2025

Study reveals how B cells safeguard high-affinity antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

19 Mar 2025