Microglia News and Research

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Kent State professor receives NIH grant to study neurological roots of fear memories

People who suffer trauma will, with few exceptions, never forget what happened to them, but a Kent State University researcher may be able to offer them the hope of living without constant fear and anxiety.

25 Oct 2018

Modeling Alzheimer’s Disease Using Microfluidics

An interview with Dr. Joseph Park, the incorporation of astrocytes into the Alzheimer’s-in-a-dish culture system and it's applications in drug development.

24 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today further progress on the Company's platform efforts in extrahepatic delivery of novel siRNA conjugates, including central nervous system (CNS) and ocular delivery in rat and non-human primates (NHPs).

3 Oct 2018

Microglia lead to increased neuro-inflammation in fibromyalgia patients, finds study

A study by Massachusetts General Hospital researchers - collaborating with a team at the Karolinska Institutet in Sweden - has documented for the first time widespread inflammation in the brains of patients with the poorly understood condition called fibromyalgia.

28 Sep 2018

Axol's Human iPSC-derived Microglia for neuroimmunology research

Our Human iPSC-derived Microglia are suitable for a variety of applications including in vitro disease models, phenotypic screening and immunology studies.

From Axol Bioscience Ltd 27 Sep 2018

Dietary fiber may delay memory loss, brain inflammation during old age

As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function.

14 Sep 2018

Tiny sensors can measure dopamine levels in the brain for more than a year

Dopamine, a signaling molecule used throughout the brain, plays a major role in regulating our mood, as well as controlling movement. Many disorders, including Parkinson's disease, depression, and schizophrenia, are linked to dopamine deficiencies.

12 Sep 2018

Particular immune cell seems to play key role in determining male or female characteristics

Researchers at the University of Maryland School of Medicine have made a surprising discovery: during fetal development, a particular immune cell seems to play a key role in determining the male or female characteristics of the brain.

12 Sep 2018

Obesity contributes to cognitive deficits by activating microglial cells, mice study shows

Obesity leads to cognitive impairment by activating microglial cells, which consume otherwise functional synapses in the hippocampus, according to a study of male mice published in JNeurosci.

From Society for Neuroscience 11 Sep 2018

Meet Axol Bioscience at 2018 Cambridge International Stem Cell Symposium

We are very pleased to support the 6th Cambridge International Stem Cell Symposium from 19 - 21 September. The annual event held by the University of Cambridge will bring together more than 400 delegates, from students to professors, to discuss the biggest fundamental and translational questions as well as celebrate the great advances being made in stem cell biology all around the world.

From Axol Bioscience Ltd 7 Sep 2018

Hypertension drugs may be used to preserve memory of lupus patients

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus.

5 Sep 2018

Study reveals sex-specific differences in mice microglia

Researchers in Berlin have described significant differences in the brain immune cells (microglia) of male and female mice.

4 Sep 2018

Scientists shed light on how dangerous inflammations are caused in the brain

The so-called CB1 receptor is responsible for the intoxicating effect of cannabis. However, it appears to act also as a kind of “sensor” with which neurons measure and control the activity of certain immune cells in the brain.

31 Aug 2018

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Researchers from Kanazawa University report in Journal of Neuroscience performed a microdialysis study on mice to determine mechanisms underlying the inflammatory response in the brain associated with fever that might be used to develop new strategies for treatment.

31 Aug 2018

Neurons play active role in triggering a defense mechanism that leads to their own damage

Rasmussen's encephalitis is a rare autoimmune disease that primarily affects children and can lead to seizures.

31 Aug 2018

KU Leuven study: Macrophages in the intestine can survive for a long time

Macrophages are specialized immune cells that destroy bacteria and other harmful organisms. KU Leuven scientists, Belgium, have come to the surprising conclusion that some macrophages in the intestines of mice can survive for quite some time.

30 Aug 2018

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer's disease.

29 Aug 2018

Scientists discover potential treatment for Alzheimer’s disease

Scientists discovered a modified version of an immune cell receptor called a toll-like receptor that could be used as a treatment for Alzheimer’s disease.

29 Aug 2018

Study provides new clues to connection between aging and neurodegeneration

For decades researchers have worked to shed light on the causes of neurodegenerative disorders, a group of devastating conditions, including Alzheimer's and Parkinson's, that involve the progressive loss of neurons and nervous system function. In recent years, numerous factors, from genetic mutations to viral infections, have been found to contribute to the development of these diseases.

23 Aug 2018

Microglia News and Research

Kent State professor receives NIH grant to study neurological roots of fear memories

Modeling Alzheimer’s Disease Using Microfluidics

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Microglia lead to increased neuro-inflammation in fibromyalgia patients, finds study

Axol's Human iPSC-derived Microglia for neuroimmunology research

Dietary fiber may delay memory loss, brain inflammation during old age

Tiny sensors can measure dopamine levels in the brain for more than a year

Particular immune cell seems to play key role in determining male or female characteristics

Obesity contributes to cognitive deficits by activating microglial cells, mice study shows

Meet Axol Bioscience at 2018 Cambridge International Stem Cell Symposium

Hypertension drugs may be used to preserve memory of lupus patients

Study reveals sex-specific differences in mice microglia

Scientists shed light on how dangerous inflammations are caused in the brain

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Neurons play active role in triggering a defense mechanism that leads to their own damage

KU Leuven study: Macrophages in the intestine can survive for a long time

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Scientists discover potential treatment for Alzheimer’s disease

Study provides new clues to connection between aging and neurodegeneration

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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