Orthopedics News and Research

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Vasopressin more effective for cardiopulmonary resuscitation

Epinephrine has been shown to be a first-choice drug for cardiopulmonary resuscitation. Nevertheless, its β-adrenergic effect probably increases myocardial oxygen consumption and leads to severe cardiac and cerebral injuries; moreover, epinephrine does not elevate long-term survival rates.

29 Aug 2014

New adhesive method for repairing sciatic nerves

When repairing nerves with adhesives, most researchers place glue directly on the nerve stumps, but this method does not fix the nerve ends well and allows glue to easily invade the nerve ends.

29 Aug 2014

EDGE gets FDA clearance for VIEW Plating System and REDUCE Fracture Plating System

EDGE Orthopaedics, a new entry in the orthopedic medical device space, is excited to announce they have received their second FDA 510(k) clearance for the VIEW Plating System and REDUCE Fracture Plating System.

28 Aug 2014

Mutant allele frequency predicts lung cancer TKI response

Tyrosine kinase inhibitor sensitivity may be predicted by the frequency of a point mutation in the epidermal growth factor receptor gene, suggests a study of Japanese patients with advanced lung adenocarcinoma.

28 Aug 2014

Gene variants linked to overactive bladder and prolapse in women

A systematic review and meta-analysis of genetic association studies reveals a number of genetic variations associated with overactive bladder and pelvic organ prolapse in women.

28 Aug 2014

High PD-L1 expression linked to reduced survival in NSCLC

Overexpression of programmed death-ligand 1 is independently associated with the presence of epidermal growth factor receptor gene mutations and poor prognosis in patients with non-small-cell lung cancer, Japanese researchers report.

28 Aug 2014

Asterias receives clearance from FDA to initiate Phase 1/2a clinical trial of AST-OPC1

Asterias Biotherapeutics Inc. has received clearance from the U.S. Food and Drug Administration to initiate a Phase 1/2a clinical trial of its product, AST-OPC1, in patients with complete cervical spinal cord injury.

27 Aug 2014

Clinical study shows long-term effectiveness of Orthocell’s Ortho-ATI™ for treatment resistant tennis elbow

Regenerative medicine company Orthocell Limited has today released results from a long-term clinical study into its Ortho-ATI™ treatment for tennis elbow that provides evidence of the durability and long term success of this treatment.

25 Aug 2014

Auxilium Pharmaceuticals' CCH drug effective against cellulite in Phase 2a study

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced positive results from a randomized, double-blind Phase 2a study of collagenase clostridium histolyticum (or CCH) for the treatment of edematous fibrosclerotic panniculopathy (EFP), commonly known as cellulite.

21 Aug 2014

EGFR biomarkers predict NSCLC response to vandetanib

Biomarker analyses of tumour samples from the ZODIAC study indicate that epidermal growth factor receptor gene copy number and mutation status may help identify the non-small-cell lung cancer patients most likely to benefit from treatment with vandetanib plus docetaxel.

20 Aug 2014

Thermo sensitive collagen hydrogel in dynamic culture enhances tissue-engineered peripheral nerve

Tissue engineering technologies offer new treatment strategies for the repair of peripheral nerve injury, but cell loss between seeding and adhesion to the scaffold remains inevitable.

19 Aug 2014

Regional anesthesia technique allows majority of patients to go home within hours of surgery

A recent study of an ultrasound-guided regional anesthesia technique, called femoral nerve block, shows that it leads to less opioid use and allows the majority of patients to go home within hours of surgery.

13 Aug 2014

Mindray net revenues increase 8.9% to $334.5 million in Q2 2014

Mindray Medical International Limited, a leading developer, manufacturer and marketer of medical devices worldwide, announced today its selected unaudited financial results for the second quarter ended June 30, 2014.

From Mindray 12 Aug 2014

New Cardio-Oncology Program to keep hearts beating strong throughout breast cancer treatments

Hearts are at risk when fighting against breast cancer - due to toxic side effects of common treatments like chemotherapy and radiation therapy.

7 Aug 2014

Auxilium Pharmaceuticals' total revenues decrease 17% to $83 million in Q2 2014

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, today announced financial results for the second quarter ending June 30, 2014. The Company highlighted important corporate, commercial, regulatory and clinical development updates from the quarter.

7 Aug 2014

PSAL students to receive free comprehensive health screening at HSS

It's a parent's worst nightmare, and it happens out of the blue. While playing a sport, often football, a teen athlete collapses on the field and doesn't make it.

7 Aug 2014

Study provides platform for detailed study of nerve injury and repair during Wallerian degeneration

Wallerian degeneration is a subject of major interest in neuroscience. A large number of genes are differentially regulated during the distinct stages of Wallerian degeneration: transcription factor activation, immune response, myelin cell differentiation and dedifferentiation.

31 Jul 2014

New research may provide better treatment options for children with cerebral palsy

Of cerebral palsy, caregivers and patients know this is an understatement: it's not easy. The permanently debilitating condition, which occurs in babies from the prenatal stage to toddlers, comes with more than its fair share of lifelong challenges - from mobility problems to developmental setbacks.

31 Jul 2014

Mercy achieves national ranking for specialty care, earns No. 2 rank in Maryland

Mercy Medical Center has been ranked nationally in three adult medical specialties (Gynecology, Orthopedics, and Neurology/Neurosurgery), named a high performer in six key adult specialties, and further recognized as the #2 hospital in the State of Maryland for 2014-15 by U.S. News & World Report.

26 Jul 2014

RI Defeats Hepatitis C project aims to eliminate HCV in Rhode Island

Lynn E. Taylor, M.D., director of The Miriam Hospital's HIV/Viral Hepatitis Coinfection program, states in the July, 2014 Rhode Island Medical Journal special edition, "RI Defeats Hep C" that eliminating hepatitis c virus infection (hep c or HCV) is feasible, can provide economic benefits, enhance capacity to address other health challenges, and improve health care disparities.

26 Jul 2014

Orthopedics News and Research

Vasopressin more effective for cardiopulmonary resuscitation

New adhesive method for repairing sciatic nerves

EDGE gets FDA clearance for VIEW Plating System and REDUCE Fracture Plating System

Mutant allele frequency predicts lung cancer TKI response

Gene variants linked to overactive bladder and prolapse in women

High PD-L1 expression linked to reduced survival in NSCLC

Asterias receives clearance from FDA to initiate Phase 1/2a clinical trial of AST-OPC1

Clinical study shows long-term effectiveness of Orthocell’s Ortho-ATI™ for treatment resistant tennis elbow

Auxilium Pharmaceuticals' CCH drug effective against cellulite in Phase 2a study

EGFR biomarkers predict NSCLC response to vandetanib

Thermo sensitive collagen hydrogel in dynamic culture enhances tissue-engineered peripheral nerve

Regional anesthesia technique allows majority of patients to go home within hours of surgery

Mindray net revenues increase 8.9% to $334.5 million in Q2 2014

New Cardio-Oncology Program to keep hearts beating strong throughout breast cancer treatments

Auxilium Pharmaceuticals' total revenues decrease 17% to $83 million in Q2 2014

PSAL students to receive free comprehensive health screening at HSS

Study provides platform for detailed study of nerve injury and repair during Wallerian degeneration

New research may provide better treatment options for children with cerebral palsy

Mercy achieves national ranking for specialty care, earns No. 2 rank in Maryland

RI Defeats Hepatitis C project aims to eliminate HCV in Rhode Island

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