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New trial method could be more efficient way to study stroke treatments

A sequential multiple assignment randomized trial allows researchers to test two hypotheses at once.

9 Jun 2017

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab.

9 Jun 2017

Opana ER – a long acting opioid painkiller, to be pulled from the markets as per FDA directive

The US Food and Drug Administration this Thursday (8th June 2017) directed pharmaceutical company Endo Pharmaceuticals to remove one of its powerful opioid painkillers Opana ER, that provides a long term relief of pain but also poses a risk of drug abuse.

9 Jun 2017

Radiation therapy critical to treating brain tumors, but linked to significant adverse effects

Radiation therapy using high-energy particles, like x-rays or electron beams, is a common and critical component in successfully treating patients with brain tumors, but it is also associated with significant adverse effects, such as neuronal loss in adjacent healthy tissues.

9 Jun 2017

IUPUI researchers find differing risks for binge drinking based on race, income and age

A new study led by Indiana University-Purdue University Indianapolis assistant professor of psychology Tamika Zapolski has found differing risks for binge drinking based on race, income and age.

9 Jun 2017

Insecticides and chemicals used to combat Zika linked to reduced motor function in infants

A chemical currently being used to ward off mosquitoes carrying the Zika virus and a commonly used insecticide that was threatened with a ban in the United States have been associated with reduced motor function in Chinese infants, a University of Michigan study found.

9 Jun 2017

Researchers define action profile of experimental drug intended to treat chronic pain

At high doses, drug candidate BIA 10-2474 binds not only to the protein that it targets, but to other proteins as well. It thus deactivates proteins that are involved in the metabolism of nerve cells.

9 Jun 2017

Older patients with diabetes who are obese may have lower risk of premature death

Among older patients with diabetes, those who are overweight or obese may have a lower risk of dying prematurely than their normal weight counterparts. The finding comes from a recent analysis of published studies.

9 Jun 2017

Higher BMI linked to increased complication risks after shoulder joint replacement surgery

For patients undergoing shoulder joint replacement surgery (arthroplasty), higher body mass index is linked to increased complications- including the need for "revision" surgery, reports a study in the June 7 issue of The Journal of Bone & Joint Surgery.

8 Jun 2017

Researchers who study HED identify mechanism that may be disrupted in male pattern baldness

It is almost axiomatic in medicine that the study of rare disorders informs the understanding of more common, widespread ailments.

8 Jun 2017

New florescent imaging technique tracks actions of key enzymes in cancer, kidney disease

Researchers at the Universities of York and Leiden have pioneered a technique which uses florescent imaging to track the actions of key enzymes in cancer, genetic disorders and kidney disease.

8 Jun 2017

IBS researchers devise nanochannels for iodide transport in cell membranes

Exchange of iodide (iodine ions) between bloodstream and cells is crucial for the health of several organs and its malfunctioning is linked to goiter, hypo- and hyperthyroidism, breast cancer, and gastric cancer.

8 Jun 2017

Cannabis use during adolescence linked to greater risk of illegal substance abuse in early adulthood

According to the study published online in the Journal of Epidemiology & Community Health, regular and occasional use of cannabis as an adolescent is linked with a greater risk of other illicit drug consumption in early adulthood. The study by Bristol's Population Health Science Institute also found that cannabis use was connected with harmful drinking and smoking. One in five adolescents are at a risk of tobacco dependency, harmful alcohol consumption, and illicit drug use.

8 Jun 2017

Tonic immobility linked to subsequent PTSD and severe depression in rape victims

Active resistance is often considered to be the "normal" reaction during rape, but a new study found that most victims may experience a state of involuntary paralysis, called tonic immobility, during rape.

8 Jun 2017

Genetic manipulation of exosomes may offer new therapeutic approach to treating pancreatic cancer

Genetic manipulation of exosomes, virus-sized particles released by all cells, may offer a new therapeutic approach to treating pancreatic cancer, according to a study at The University of Texas MD Anderson Cancer Center.

8 Jun 2017

Study disrupts conventional wisdom that uterine fibroids cause miscarriages

A 10-year study, led by Vanderbilt University Medical Center professor of Obstetrics and Gynecology Katherine Hartmann, M.D., Ph.D., disrupts conventional wisdom that uterine fibroids cause miscarriages.

8 Jun 2017

Researchers find link between maternal grain consumption during pregnancy and kids' obesity by age 7

Children born to women with gestational diabetes whose diet included high proportions of refined grains may have a higher risk of obesity by age 7, compared to children born to women with gestational diabetes who ate low proportions of refined grains, according to results from a National Institutes of Health study.

8 Jun 2017

X linked News and Research

New trial method could be more efficient way to study stroke treatments

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

Opana ER – a long acting opioid painkiller, to be pulled from the markets as per FDA directive

Radiation therapy critical to treating brain tumors, but linked to significant adverse effects

IUPUI researchers find differing risks for binge drinking based on race, income and age

Insecticides and chemicals used to combat Zika linked to reduced motor function in infants

Researchers define action profile of experimental drug intended to treat chronic pain

Older patients with diabetes who are obese may have lower risk of premature death

Higher BMI linked to increased complication risks after shoulder joint replacement surgery

Researchers who study HED identify mechanism that may be disrupted in male pattern baldness

New florescent imaging technique tracks actions of key enzymes in cancer, kidney disease

IBS researchers devise nanochannels for iodide transport in cell membranes

Cannabis use during adolescence linked to greater risk of illegal substance abuse in early adulthood

Tonic immobility linked to subsequent PTSD and severe depression in rape victims

Genetic manipulation of exosomes may offer new therapeutic approach to treating pancreatic cancer

Study disrupts conventional wisdom that uterine fibroids cause miscarriages

Researchers find link between maternal grain consumption during pregnancy and kids' obesity by age 7

UM SOM scientists identify mutated gene that may be key player in heart disease

Spousal engagement in shared glycemic control activities may help patients with type 2 diabetes

Exposure to particulate air pollution linked to increased risk of death in liver cancer patients

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The role of UV-Vis in biopharma QC

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