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Cultured cartilage cells from the nasal septum could help relieve osteoarthritis in the knee

Cartilage cells from the nasal septum can not only help repair cartilage injuries in the knee – according to researchers from the University of Basel and the University Hospital of Basel, they can also withstand the chronic inflammatory tissue environment in osteoarthritis and even counteract the inflammation.

1 Sep 2021

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Human evolution has provided us a level of protection from the existential threat of cold temperature with the capacity to produce heat from fat stored in the body.

1 Sep 2021

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

1 Sep 2021

Family of proteins could be effective in reducing damage from ischemic stroke

Boosting a family of naturally occurring proteins that dampens inflammation in the body has been shown to be effective in reducing damage from an ischemic stroke, according to preclinical researchers at The University of Texas Health Science Center at Houston.

1 Sep 2021

Association between COVID-19 mitigation measures and preterm birth rate in China

A new study published in British Medical Journal Global Health addresses the effect of COVID-19 mitigation measures on the preterm birth rate in China.

31 Aug 2021

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Sepsis occurs when the body works so hard to fight an infection that the over-activated immune system harms a patient's own tissues as collateral damage.

31 Aug 2021

Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Liquid biopsies detect tumor DNA in blood or urine samples. Two studies led by Washington University School of Medicine in St. Louis describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors.

31 Aug 2021

Abdominal fat and weak muscles associated with loss of gait speed in older people

Weak muscles and abdominal fat are a dangerous combination for older people who have difficulty walking.

31 Aug 2021

Researchers develop new drug-free treatment to accelerate healing of chronic diabetic wounds

About one-fourth of people with diabetes develop painful foot ulcers, which are slow to heal due to low oxygen in the wound from impaired blood vessels and increased inflammation. These wounds can become chronic, leading to poor quality of life and potential amputation.

31 Aug 2021

Researchers identify biomarkers for rare, serious complication in children with COVID-19

The study focused on multisystem inflammatory syndrome in children (MIS-C), an inflammatory response involving multiple organs that can occur weeks after infection with SARS-CoV-2, the virus that causes COVID-19.

31 Aug 2021

$1.3 million in NIH funding to enable drug delivery technology research

Two National Institute of Health grants totaling over $1.3 million will enable research into antibody-mediated drug delivery technology for the treatment of cancer and autoimmune disorders. L. Nathan Tumey, assistant professor of pharmaceutical sciences at Binghamton University, State University of New York, is the Principal Investigator on both grants - $1.2 million from the National Institute of General Medical Sciences and $150,000 from the National Institute of Allergy and Infectious Diseases.

31 Aug 2021

Coronavirus buildup in the lungs is likely behind high mortality rates

A buildup of coronavirus in the lungs is likely behind the steep mortality rates seen in the pandemic, a new study finds.

31 Aug 2021

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Octapharma USA today announced the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has awarded seven years of marketing exclusivity for Octagam® 10% [Immune Globulin Intravenous (Human)], the first and only intravenous immunoglobulin (IVIg) to be indicated for the treatment of adult dermatomyositis (DM).

31 Aug 2021

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

Aging-US published "The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence" which reported that cellular senescence may be a side effect of chemotherapy and other anti-cancer treatments that may promote inflammation and paracrine secondary senescence in healthy tissues.

31 Aug 2021

Researchers identify 55 lingering effects of COVID-19

As COVID-19 hospitalizations once again soar in a fourth surge more than 18 months after the pandemic started, some patients continue to experience symptoms long after recovering from COVID, according to a Houston Methodist study recently published in Nature's Scientific Reports.

30 Aug 2021

Will mRNA vaccine boosters be required for SARS-CoV-2 variants?

A new study shows that the highly effective mRNA Moderna vaccine designed against the original SARS-CoV-2 strain may lose some efficacy as new variants arise.

30 Aug 2021

New study analyzes altered gene expression in severe COVID-19

In a paper recently uploaded to the bioRxiv* preprint server, the genetic link between COVID-19 severity and gene expression is investigated, hoping to allow early identification of otherwise healthy individuals that will likely require hospitalization if infected.

30 Aug 2021

Inflammation News and Research

Cultured cartilage cells from the nasal septum could help relieve osteoarthritis in the knee

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

Family of proteins could be effective in reducing damage from ischemic stroke

Association between COVID-19 mitigation measures and preterm birth rate in China

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Abdominal fat and weak muscles associated with loss of gait speed in older people

Researchers develop new drug-free treatment to accelerate healing of chronic diabetic wounds

Researchers identify biomarkers for rare, serious complication in children with COVID-19

$1.3 million in NIH funding to enable drug delivery technology research

Coronavirus buildup in the lungs is likely behind high mortality rates

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

Researchers identify 55 lingering effects of COVID-19

Will mRNA vaccine boosters be required for SARS-CoV-2 variants?

New study analyzes altered gene expression in severe COVID-19

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Study highlights the robustness of miRNA modulation during aging process

NYU Tandon describes novel peptide with broad therapeutic potential to combat multiple diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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