Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Highly sensitive ELISA method for analysis of CET in plasma samples

This article explores the development, full optimization and validation study of a highly sensitive and selective ELISA for determination of cetuximab (CET) in human plasma samples.

23 Feb 2018

Efficacy of cancer immunotherapy increased by deactivating tumor defence mechanism

Novel bifunctional immunotherapeutic agents have been developed that, as well as deactivating key immune checkpoints,deactivate the tumor's protective response.

23 Feb 2018

Modifications in HIV test enable rapid detection of Zika virus, study states

A new comprehensive study details a novel test for Zika virus, which utilizes saliva for rapid identification of the diagnostic markers of the virus.

23 Feb 2018

Scientists discover new treatment approach to curb severe myocarditis

The outcome of viral myocarditis is closely associated with the immune response of the affected individual. An inhibitor of the immunoproteasome, a protein degradation complex in immunocompetent cells, reduces the extent of the inflammation and thus also the damage to the heart during myocarditis.

22 Feb 2018

Study finds novel therapeutic strategy that preserves neuromuscular synapses in ALS mouse model

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, causes lethal respiratory paralysis within several years of diagnosis. There are no effective treatments to slow or halt this devastating disease.

21 Feb 2018

AbbVie and Voyager Therapeutics collaborate to develop new treatments for tauopathies

AbbVie, a global biopharmaceutical company, and Voyager Therapeutics, Inc., a clinical-stage gene therapy company, today announced that they have entered into an exclusive strategic collaboration and option agreement to develop and commercialize vectorized antibodies directed against tau for the treatment of Alzheimer's disease and other neurodegenerative diseases.

20 Feb 2018

Immune history influences person's response to flu vaccine

New research on why the influenza vaccine was only modestly effective in recent years shows that immune history with the flu influences a person's response to the vaccine.

20 Feb 2018

New blood test shows promise to revolutionize diagnosis of tick-borne diseases

A new blood test called the Tick-Borne Disease Serochip (TBD Serochip) promises to revolutionize the diagnosis of tick-borne disease by offering a single test to identify and distinguish between Borrelia burgdorferi, the pathogen responsible for Lyme disease, and seven other tick-borne pathogens.

18 Feb 2018

Psoriasis drug also effective at reducing aortic inflammation

Ustekinumab, sold under the name Stelara, is approved by the U.S. Food and Drug Administration to treat psoriasis, psoriatic arthritis, and Crohn's Disease. Researchers wanted to know if the benefits of the drug go beyond clearing the skin.

18 Feb 2018

Using Smartphones for Cancer Diagnosis and Management

Dr. Castro is a translational oncologist with experience developing and harnessing nanotechnology and molecular imaging platforms for cancer purposes. His work offers a “less is more” approach — to generate robust cancer analyses using scant amount of specimens. Dr. Castro’s research has included funding from the V Foundation for Cancer Research, National Institutes of Health, Ovarian Cancer Research Fund, and the Department of Defense.

From Pittcon 14 Feb 2018

Oncolytic virus alerts the immune system to attack tumors

A new UC San Francisco study has shown that a cancer-killing virus currently in clinical trials may function as a cancer vaccine - in addition to killing some cancer cells directly, the virus alerts the immune system to the presence of a tumor, triggering a powerful, widespread immune response that kills cancer cells far outside the virus-infected region.

14 Feb 2018

Scientists unravel immune cascade that drives tissue damage, complications in chlamydia infections

Closing a critical gap in knowledge, Harvard Medical School scientists have unraveled the immune cascade that fuels tissue damage and disease development in chlamydia infection - the most common sexually transmitted disease in the United States.

13 Feb 2018

Scientists develop new array to identify biomarkers for wide range of diseases

Scientists have developed a way to identify biomarkers for a wide range of diseases by assessing the antibodies we are making to the complex sugars coating our cells.

12 Feb 2018

Abzena selects Sartorius Stedim Biotech as preferred equipment supplier in the U.S

Abzena plc, the life sciences group providing services and technologies to enable the development and manufacture of biopharmaceutical products, has selected Sartorius Stedim Biotech as its preferred equipment supplier in the U.S.

From Sartorius 9 Feb 2018

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Production of conventional vaccines, which involves the use of live-attenuated or purified protein subunits of pathogens, is a long and complex process. Nucleic acid vaccines are safer alternatives, and allow easy adjustment of antigen to target specific pathogens.

9 Feb 2018

Scientists design new triple labeling technique to analyze stem cell division

A joint team of scientists from Russia and the United States designed a method for marking dividing stem cells with three different labels.

8 Feb 2018

Researchers develop novel antibody-based therapy to treat organ fibrosis

Fibrosis can be triggered by many events- surgery, injury, disease- but regardless of the cause, it's characterized by accumulating masses of collagen-packed scar tissue that can permanently damage compromised organs.

6 Feb 2018

Scientists develop new system to match genetic anomalies with precision medicine treatments

A team of computer scientists from the University of Delaware and Georgetown University has developed a new system to rapidly determine which cancer drugs are likely to work best given a patient's genetic markers.

6 Feb 2018

German researchers find way to accurately differentiate prostate cancer from benign tissue

Using nuclear medicine, German researchers have found a way to accurately differentiate cancerous tissue from healthy tissue in prostate cancer patients. The research is highlighted in the February issue of The Journal of Nuclear Medicine.

6 Feb 2018

Early and targeted treatment of dnDSA preserves allograft function

Development of de novo donor-specific antibodies (dnDSA) is known to cause graft failure. Therefore, a protocol aimed at prospective monitoring and treating dnDSA--before it can cause graft damage--was developed for kidney transplant recipients at Children National Health System.

5 Feb 2018