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Neuropathology of COVID-19 patients caused by infection of brain pericytes

Recently, researchers from the UK and Sweden used highly sensitive multiplexed immunohistochemistry to study the brain tissue of COVID-19 patients and controls to analyze ACE2 expression in brain pericytes of patients with neurological symptoms. They also used spatial immunophenotyping to assess inflammation in brain tissue of COVID-19 patients.

31 May 2021

Researchers review 50 years of progress in women's health

Debates over women's health have long been contentious, but have also resulted in significant improvements in areas like equitable access to health care and survivorship. But the overall picture remains far from perfect.

31 May 2021

Researchers assess the prognostic value of cardiac troponin I in COVID-19 patients

Corona Virus Disease (COVID -19) patients primarily appear with respiratory issues and viral pneumonia. The patients may also present cardiovascular issues includes early signs of acute myocardial injury.

29 May 2021

FDA approves targeted therapy for tumors with KRAS mutations

Today, the U.S. Food and Drug Administration approved Lumakras (sotorasib) as the first treatment for adult patients with non-small cell lung cancer whose tumors have a specific type of genetic mutation called KRAS G12C and who have received at least one prior systemic therapy.

29 May 2021

FDA seeks $6.5 billion for investments in core food safety, critical public health infrastructure

The U.S. Food and Drug Administration is requesting a total budget of $6.5 billion as part of the President's fiscal year (FY) 2022 budget - a nearly 8% ($477 million) increase over the agency's FY 2021 funding level for investments in critical public health infrastructure, core food safety and medical product safety programs and other vital public health programs.

29 May 2021

New resolution urges Member States to focus on prevention and management of diabetes, obesity

A new resolution urges Member States to raise the priority given to the prevention, diagnosis and control of diabetes as well as prevention and management of risk factors such as obesity.

29 May 2021

Africa has the highest death rates among critically ill COVID-19 patients, shows study

Africa has the highest death rates in the world among critically ill COVID-19 patients, with limited intensive care resources a major factor, a study says.

29 May 2021

Platinum chemotherapy can cause leukaemia in children with neuroblastoma, shows study

New research indicates that certain anti-cancer therapies may hasten cellular aging, where changes in the DNA of patients may contribute to greater inflammation and fatigue. The findings are published by Wiley early online in CANCER, a peer-reviewed journal of the American Cancer Society.

29 May 2021

New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

A new study, published in Nano Letters, describes an effective new COVID-19 vaccine candidate based on a messenger ribonucleic acid (mRNA) platform.

28 May 2021

Study links barotrauma to COVID-19 in younger patients

To better understand the possible relationship between severe infection and poor in-hospital outcomes, researchers from the Internal Medicine, and the Pulmonary Critical Care Medicine, Rutgers University, Newark, USA, presented a case series linking barotrauma to COVID-19 in younger patients.

28 May 2021

In California, nursing home owners can operate after they’re denied a license

The pandemic has highlighted poor care in America’s nursing homes, where nearly 175,000 people have died of covid-19 — a third of all deaths from the disease nationwide.

28 May 2021

Plant-based food can reduce heart disease risk by 10% research shows

In a new study, researchers have found that substituting an animal protein for dinner with a plant protein could reduce the risk of cardiovascular disease by 10%.

27 May 2021

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

COVID-19 was initially described as lung inflammation, or pneumonia, in older adults. However, we now know that SARS-CoV-2 infections can cause a wide range of symptoms in people of all ages, ranging from no symptoms at all to systemic inflammation and even death.

27 May 2021

Oligo DNA improves differentiation of skeletal muscles exacerbated by diabetes

Skeletal muscle is the largest organ in the body that accounts for 30 to 40% of body weight and is responsible for multiple functions such as energy metabolism and heat production.

27 May 2021

Reducing COVID-19 burden with monoclonal antibodies and vaccination

Researchers in the United States, the UK and France have shown that using antiviral monoclonal antibodies in combination with vaccination can be expected to suppress the transmission of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) and reduce the burden of coronavirus disease 2019 (COVID-19) more than vaccination alone.

26 May 2021

Zoonotic and vector-borne emerging tropical diseases pose a constant threat

A recent article published in the journal Frontiers in Tropical Diseases assessed the threat of emerging zoonotic and vector-borne tropical diseases.

26 May 2021

Human T cells can target more than 1,400 sites on SARS-CoV-2 virus

In a new paper, scientists from La Jolla Institute for Immunology (LJI) bring together research findings from COVID-19 researchers around the world.

25 May 2021

Repurposed gout medication (probenecid) shows potent inhibition of SARS-CoV-2 replication

New research by a team of scientists in the USA describes the potential utility of a drug called probenecid, commonly used to treat gout, to treat this devastating viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative virus of COVID-19.

25 May 2021

Researchers explore strategies that could help the homeless during pandemics

A team of UBC Okanagan researchers is looking at strategies that could help the homeless during a pandemic.

25 May 2021

DEFINE: Trial designed to test repurposed treatments in patients with COVID-19

A team of scientists from the United Kingdom has designed an experimental medicine trial to evaluate the safety/tolerability, and efficacy profiles of a panel of candidate repurposed therapies in coronavirus disease 2019 (COVID-19) patients. A detailed outline of the trial is currently available on the medRxiv* preprint server.

25 May 2021