Coronavirus News and Research

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Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Researchers discuss mutations in the NTD of the spike protein, which contains an antigenic “supersite” and is the target for nAbs.

24 Oct 2021

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Researchers report the binding and pseudo-neutralizing antibody titers elicited after patients had received either the Pfizer-BioNTech or AstraZeneca vaccines.

24 Oct 2021

Mapping the molecular gene signatures of respiratory viruses, including SARS-CoV-2

Researchers compare a large cohort of transcriptomic dataset maps of gene regulation by SARS-CoV-2 infection.

24 Oct 2021

Vaccination data from Puerto Rico strongly supports COVID19 booster shots

In a recent study, researchers from the U.S. examined the vaccine effectiveness against SARS-CoV-2 infections in Puerto Rico.

24 Oct 2021

Nurses experience suicidal ideation in greater numbers than other workers

Mayo Clinic researchers report that nurses in the U.S. experience suicidal ideation in greater numbers than other general workers and those who do are less likely to tell anyone about it. The findings appear in the American Journal of Nursing.

22 Oct 2021

Study examines effectiveness of BNT162b2 vaccine against Delta variant in adolescents

The Clalit Research Institute, in collaboration with researchers from Harvard University, analyzed one of the world's largest integrated health record databases to examine the effectiveness of the Pfizer/BioNTech BNT162B2 vaccine against the Delta variant of SARS-CoV-2 among adolescents.

22 Oct 2021

CDC endorses ACIP's recommendation for COVID-19 booster shots in certain populations

Today, CDC Director Rochelle P. Walensky, M.D., M.P.H., endorsed the CDC Advisory Committee on Immunization Practices' (ACIP) recommendation for a booster shot of COVID-19 vaccines in certain populations.

22 Oct 2021

Chemical substance may specifically inhibit both SARS-CoV-2 proteases and human protease

Researchers tested analogs of disulfiram on SARS-CoV-2 Mpro and PLpro to find more efficient and effective inhibitors that take advantage of disulfiram’s mechanism of binding to the cysteine residue.

22 Oct 2021

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

A team of researchers measured the infectivity of SARS-CoV-2 variants C.1.2, Mu, and Delta+501S spike proteins and determined the susceptibility to neutralizing antibodies.

22 Oct 2021

SARS-CoV-2 anti-nucleocapsid antibodies reduce risk of reinfection for at least eight months

A new study concludes that at least with predominantly wild-type variants, the risk of reinfection with the virus among unvaccinated people is reduced by 80% or more.

22 Oct 2021

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Scientists studied the efficacy of an intranasal booster composed of beta variant-spike protein S1 with IL-15 and TLR agonists in macaques that were previously immunized.

22 Oct 2021

Replication of SARS-CoV-2 variants in different cell and organ models

In this study, the replication of B.1.1.7 viruses was analyzed in different cell and organ models and dwarf hamsters.

22 Oct 2021

Development of a safe and effective COVID-19 nanoparticle vaccine

Researchers from ReVacc scientific have attempted to demonstrate the effectiveness of a new vaccine, REVC-128, two weeks post-administration.

22 Oct 2021

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Researchers from Stanford University have been attempting to create a hydrogel-based vaccine delivery system that could improve the immune response's strength and duration.

22 Oct 2021

New AI-based tool helps clinicians understand and better predict adverse effects of COVID-19

The symptoms and side effects of Covid-19 are scattered across a diagnostic spectrum. Some patients are asymptomatic or experience a mild immune response, while others report significant long-term illnesses, lasting complications, or suffer fatal outcomes.

22 Oct 2021

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Amidst growing concerns on the use and potential benefits of convalescent plasma therapy, a research group in the United States has identified three human antibodies (Abs) that, when combined, demonstrate both robust viral suppressive properties against all tested severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Variants of Concern (VoC) in vitro and profound antiviral efficacy in vivo.

22 Oct 2021

Vaccinating adolescents may reduce the impact of COVID-19, according to a UK modeling study

A recent study from the United Kingdom, published in the open-access journal Vaccines, implies that vaccinating adolescents and children may be pivotal in reducing infections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as ensuing coronavirus disease (COVID-19) morbidity and mortality across all age groups.

21 Oct 2021

Honeybees can be trained to identify SARS-CoV-2 infected samples, say scientists

In a recent study published on the bioRxiv* pre-print server, researchers from the Netherlands successfully trained honeybees (Apis mellifera) to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected minks (Neovison vison) using Pavlovian conditioning protocols.

21 Oct 2021

Antisocial and prosocial behavior during COVID-19

A new study aims to determine whether individuals with antisocial behaviors are more susceptible to COVID-19.

21 Oct 2021

Comparative effectiveness of ChAdOx1 and BNT162b2 COVID-19 vaccines

In a recent study, researchers compared the efficacy of the Pfizer-BioNTech and Oxford-AstraZeneca COVID-19 vaccines against infection SARS-CoV-2.

21 Oct 2021

Coronavirus News and Research

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Mapping the molecular gene signatures of respiratory viruses, including SARS-CoV-2

Vaccination data from Puerto Rico strongly supports COVID19 booster shots

Nurses experience suicidal ideation in greater numbers than other workers

Study examines effectiveness of BNT162b2 vaccine against Delta variant in adolescents

CDC endorses ACIP's recommendation for COVID-19 booster shots in certain populations

Chemical substance may specifically inhibit both SARS-CoV-2 proteases and human protease

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

SARS-CoV-2 anti-nucleocapsid antibodies reduce risk of reinfection for at least eight months

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Replication of SARS-CoV-2 variants in different cell and organ models

Development of a safe and effective COVID-19 nanoparticle vaccine

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

New AI-based tool helps clinicians understand and better predict adverse effects of COVID-19

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Vaccinating adolescents may reduce the impact of COVID-19, according to a UK modeling study

Honeybees can be trained to identify SARS-CoV-2 infected samples, say scientists

Antisocial and prosocial behavior during COVID-19

Comparative effectiveness of ChAdOx1 and BNT162b2 COVID-19 vaccines

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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