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Children's Oakland recruits patients for deferiprone clinical trial to treat PKAN

A groundbreaking, international clinical trial of an iron chelation drug, deferiprone, to treat the rare and devastating neurodegenerative disease, pantothenate kinase-associated neurodegeneration (PKAN), began last month at the trial's only North American site, Children's Hospital & Research Center Oakland.

17 Jan 2013

SyNAPSe® Trial by BHR Pharma deemed to have no safety issues according to DSMB

BHR Pharma, LLC announced today that the SyNAPSe® Trial's independent Data and Safety Monitoring Board (DSMB) evaluated safety data from 803 randomized patients and determined that no issues exist; therefore, the trial may continue towards its intended completion.

17 Jan 2013

TMD pain might reflect physical manifestation of anxiety or depression

There is an ongoing debate about the role of psychological disorder symptoms as risk factors for temporomandibular joint (TMJ) pain. Previous studies have associated depression and TMJ pain but large scale studies have not been performed.

17 Jan 2013

WHO reports unprecedented progress against 17 neglected tropical diseases

WHO reports unprecedented progress against 17 neglected tropical diseases, thanks to a new global strategy, a regular supply of quality assured, cost-effective medicines and support from global partners.

17 Jan 2013

India marks two years since last diagnosed polio case

On January 13, India "completed two years since the last case of the crippling disease was reported ... a huge achievement for a country that as recently as 2009 reported 741 cases of polio -- more than any other country in the world, and almost half of cases reported globally that year," the Wall Street Journal's "India Real Time" blog reports.

16 Jan 2013

WHO recommends switching to injectable polio vaccine

"[T]his month the World Health Organization (WHO) in Geneva, Switzerland, proposed a shift in [polio] vaccination strategy from oral vaccines to injected ones that may have to be administered in clinics," Nature reports, adding, "The change is needed to mop up the last remaining pockets of polio, but experts say that it poses challenges in [rural areas], which have poor access to health care."

16 Jan 2013

FDA approves Santarus’ UCERIS for induction of remission in patients with ulcerative colitis

Santarus, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved UCERIS (budesonide) extended release tablets for the induction of remission in patients with active, mild to moderate ulcerative colitis.

16 Jan 2013

CHOP to study antibiotic delivery to children after hospitalization for serious bacterial infection

The Children's Hospital of Philadelphia (CHOP) was awarded nearly $2M in research funding from the Patient-Centered Outcomes Research Institute (PCORI) to study antibiotic delivery to children returning home after hospitalization for a severe bacterial infection.

16 Jan 2013

Pfizer’s Quillivant XR now available in the U.S. for treatment of ADHD

Pfizer Inc. today announced that Quillivant XR (methylphenidate hydrochloride) CII for extended-release oral suspension is now available in the U.S. for the treatment of attention deficit hyperactivity disorder (ADHD).

16 Jan 2013

Diospyrin inactivates a drug target for tuberculosis in new way

A compound from the South African toothbrush tree inactivates a drug target for tuberculosis in a previously unseen way.

16 Jan 2013

Vitamin D claims for knee osteoarthritis questioned

The benefit of taking vitamin D supplements for the treatment of knee osteoarthritis has been challenged in a study published in JAMA.

14 Jan 2013

Morphine not first choice after neonatal surgery

Neonates and infants undergoing major surgery should be treated with postoperative intermittent intravenous acetaminophen as opposed to continuous morphine, research suggests.

14 Jan 2013

Dental diversion plan eases burden in busy EDs

Hospital emergency departments may benefit from having a diversion plan in place to deal with dental patients, say US researchers writing in the Journal of Oral and Maxillofacial Surgery.

14 Jan 2013

Human papillomavirus an etiologic factor in 6% of OCSCC cases

High-risk human papillomavirus is an etiologic factor in approximately 6% of cases of oral cavity squamous cell carcinoma, according to epidemiologic research.

14 Jan 2013

Communication key in helping patients adhere to medicine

Patients are less likely to take their medications properly if they feel their family doctor or other primary care clinician is failing to communicate with them adequately, suggests a US study published in the Archives of Internal Medicine.

14 Jan 2013

UCSF teams to study new ways to reduce childhood mortality and disease in developing nations

Two UCSF teams have received a total of $16 million from the Bill & Melinda Gates Foundation to study new ways to significantly reduce childhood mortality and disease in developing nations.

11 Jan 2013

Roundup: Advocates watching Calif. budget for Medi-Cal cuts; Mich. AG to appeal same-sex health benefits ruling; Kansas city seeks to extend health care tax

Brown's proposed budget will outline his plans for expanding health coverage under the new federal health care law, which is set to require increased coverage beginning in January 2014. The law will put hundreds of thousands of new enrollees into California's public insurance program, but the governor has raised concerns about what that will cost.

11 Jan 2013

Cholera could be contained in Haiti by vaccinating less than half the population

Cholera could be contained in Haiti by vaccinating less than half the population, University of Florida researchers suggest in a paper to be published Thursday in the journal Scientific Reports.

11 Jan 2013

New information on insulin and cell bonding mechanics

The discovery of insulin nearly a century ago changed diabetes from a death sentence to a chronic disease. Today a team that includes researchers from Case Western Reserve University School of Medicine announced a discovery that could lead to dramatic improvements in the lives of people managing diabetes.

11 Jan 2013

Tips for parents to safely help relieve child's flu symptoms

Doctors' offices are teeming with patients suffering from one of the worst outbreaks of cold and flu season in recent years. The Centers for Disease Control and Prevention has said that flu is at an elevated level across the nation. Though virus symptoms vary by age, children are especially vulnerable since they are unable to take over-the-counter medications to help alleviate symptoms.

10 Jan 2013