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Gaining culturally appropriate knowledge can help provide more effective healthcare

Mary E. Jones, MD, MPH, is the child advocacy program director and an essential part of the Loyola University Health System pediatric team. In addition to her extensive knowledge in the medical care of children, her expertise in understanding the signs of child maltreatment help Loyola provide complete care to some of the most at-risk patients.

1 Mar 2012

IOM report identifies options that could further improve information obtained from pediatric studies

Federal laws that motivate or require drug and biologic developers to conduct pediatric studies have yielded beneficial information to guide the use of medications in children, says a new report by the Institute of Medicine. Still, studies involving children continue to be limited, especially in certain areas such as medications' use in newborns and long-term safety and effectiveness in children.

1 Mar 2012

'Call to action' on wrong-route injections in anesthesia

Worldwide changes in catheter system design are urgently needed to prevent serious complications caused by accidental injection of drugs into the wrong location, according to a special editoral in the March issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

1 Mar 2012

CD4 T cells can directly kill HIV-infected cells

A subpopulation of the immune cells targeted by HIV may play an important role in controlling viral loads after initial infection, potentially helping to determine how quickly infection will progress. In the February 29 issue of Science Translational Medicine, a team of researchers from the Ragon Institute of Massachusetts General Hospital (MGH), MIT and Harvard describe finding a population of HIV-specific CD4 T cells - cells traditionally thought to direct and support activities of other immune cells - that can directly kill HIV-infected cells.

1 Mar 2012

U-M summit to focus on shortage of medical technologies for children

The University of Michigan is hosting the three-day summit that will focus attention on the widespread shortage of medical technologies to help sick children.

From Medtronic 1 Mar 2012

Loss of STAT1 transcription factor causes breast cancer development

Breast cancer represents about a fifth of all cancers diagnosed in women. The reasons for the rapid progression of the disease remain relatively poorly understood but recent work in the group of Veronika Sexl at the University of Veterinary Medicine, Vienna has pointed the finger strongly at loss or inactivation of the transcription factor STAT1.

1 Mar 2012

Gluten-free, casein-free diet more effective in improving ASD behaviors and symptoms

A gluten-free, casein-free diet may lead to improvements in behavior and physiological symptoms in some children diagnosed with an autism spectrum disorder (ASD), according to researchers at Penn State. The research is the first to use survey data from parents to document the effectiveness of a gluten-free, casein-free diet on children with ASD.

1 Mar 2012

Senate vote on contraception policy set for Thursday

With the political stakes high, lawmakers are expected to vote Thursday on a Republican measure to let employers opt out of covering any health treatment they find morally objectionable.

1 Mar 2012

South African researchers call for new framework to help prioritize global mental health

"For mental health to gain significant attention, and funding from policymakers globally, it is not enough to convince people that it has a high disease burden but also that there are deliverable and cost-effective interventions -- according to South African researchers writing in this week's PLoS Medicine," a PLoS press release reports.

1 Mar 2012

New system improves chances of pregnancy during IVF

A novel system for processing embryos during IVF treatment has been shown to significantly improve the chances of pregnancy - by more than a quarter.

1 Mar 2012

Blog examines use of medicine as weapon of war

In this post in IntraHealth International's "Global Health" blog, Editorial Manager Susanna Smith responds to an editorial published in the Lancet earlier this month that "issued a dire warning to the international medical community" about the use of medicine as a weapon of war in Syria, writing, "It is just the latest in a series of reports from across the Middle East on how medical care and medical professionals and facilities are being used to inflict politically motivated violence."

1 Mar 2012

Ruxolitinib boosts QOL and survival for patients with myelofibrosis

A drug that relieves the severe symptoms of a life-threatening bone marrow cancer called myelofibrosis also improves the survival of patients with the disease, according to a phase III clinical trial published in the March 1 edition of New England Journal of Medicine.

1 Mar 2012

Aging does not appear to be a factor in poor sleep

Aging does not appear to be a factor in poor sleep, a new survey of more than 150,000 Americans shows. In fact, subjective sleep quality seems to improve over a lifetime, with the fewest complaints coming from people in their 80s.

1 Mar 2012

State roundup: Mass. Gov. says state health reform easing cost increases; N.J. localities overpay on health coverage; Pa. cuts raise ire

At a speech to the American Cancer Society, Gov. Deval Patrick says that Massachusetts health reform has led to significant improvements in cancer screening. ... Patrick also calculates that current health care cost control efforts are enabling the state to "avoid nearly a billion dollars in cost increases in this fiscal year and another several hundred million more next year."

1 Mar 2012

Inhaled interferon-gamma may effectively treat IPF

Inhaled interferon-gamma may be an effective treatment for idiopathic pulmonary fibrosis (IPF), a chronic and progressive form of lung disease caused by excessive formation of fibrotic, or scar tissue, in the lungs, according to an article published in Journal of Aerosol Medicine and Pulmonary Drug Delivery, a peer-reviewed journal from Mary Ann Liebert, Inc.

1 Mar 2012

More than 80% of anesthesiologists have been involved in surgical catastrophes

More than 80 percent of anesthesiologists have been involved in a catastrophic event involving death or injury to a patient during surgery, suggests a survey study in the March issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

1 Mar 2012

Scientists develop safer and more accurate way to administer warfarin

A team of global scientists, led by researchers at Intermountain Medical Center in Salt Lake City, has developed a safer and more accurate way to administer warfarin, one of the most commonly prescribed but also potentially dangerous medications in the United States.

1 Mar 2012

NEJM publishes results from two Jakafi Phase III studies on MF

The New England Journal of Medicine (NEJM) today published results from two Phase III studies (COMFORT-I and COMFORT-II) of Jakafi (ruxolitinib), a JAK1 and JAK2 inhibitor recently approved by the Food and Drug Administration (FDA) for the treatment of intermediate or high-risk myelofibrosis.

1 Mar 2012

Inhibitory effect of serotonin 1A receptor is extremely small in people with depression

Researchers at the MedUni Vienna have, for the first time, investigated the influence of the serotonin system on the default mode network (DMN) in the human brain and discovered that, in people with depression, the inhibitory effect of the serotonin 1A receptor is extremely small. This means, says Siegfried Kasper, Head of the University Department of Psychiatry and Psychotherapy, that affected patients "are virtually never able to be mentally calm".

1 Mar 2012

First clinical assessment of how interferon fights infections in people

A drug once taken by people with HIV/AIDS but long ago shelved after newer, modern antiretroviral therapies became available has now shed light on how the human body uses its natural immunity to fight the virus—work that could help uncover new targets for drugs.

1 Mar 2012