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Array BioPharma announces positive results from ARRY-502 Phase 2 trial for allergic asthma

Array BioPharma Inc. today announced positive results from a placebo-controlled, randomized, double‑blind Phase 2 trial in mild to moderate persistent allergic asthma for ARRY-502, an oral CRTh2 antagonist.

23 Jul 2013

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

P53 is a tumor suppressor gene. The gene encodes for a protein that monitors the state of the cell. If something goes wrong, it stops the cell from dividing or causes the cell to commit suicide. I call it the “guardian of the genome” as it is the molecule that seems to keep cells normal. It is one of our big defenses against cancer.

22 Jul 2013

High arsenic levels in rice pose potential threat to human health: Study

High levels of arsenic in rice have been shown to be associated with elevated genetic damage in humans, a new study has found.

22 Jul 2013

BioCryst completes BCX4161 Phase 1 clinical trial for treatment of hereditary angioedema

BioCryst Pharmaceuticals, Inc. announced that the randomized, placebo-controlled, Phase 1 clinical trial of orally-administered BCX4161 in healthy volunteers successfully met all of its objectives.

22 Jul 2013

Bacillus-derived Hyaluronic acid from Novozymes Biopharma, Hyasis®, increases in vitro drug release time from under 10 minutes to approximately 15 hours

An investigation undertaken by Novozymes Biopharma DK has shown that when the corticosteroid dexamethasone is formulated in a cross-linked Hyaluronic acid (HA) hydrogel, the drug’s in vitro release time increases from under 10 minutes to approximately 15 hours. In addition, the in vivo half-life of dexamethasone is shown to plateau with stable dexamethasone concentration up to four hours after injection.

22 Jul 2013

Vegetation may not protect people from ozone pollution, says new research

During heat waves - when ozone production rises - plants' ozone absorption is curtailed, leaving more pollution in the air, and costing an estimated 460 lives in the UK in the hot summer of 2006.

20 Jul 2013

EU-funded project examines dietary habits in people with inadequate nutrition

Until now, we have had very little understanding of the extent of malnutrition in Europe, especially in populations at risk of poverty. Now, an EU-funded project calledCHANCE, aims to address the dietary habits in people with inadequate nutrition.

20 Jul 2013

NKX2-8 mutation in dogs may be a risk factor for human neural tube defects, say researchers

A gene related to neural tube defects in dogs has for the first time been identified by researchers at the University of California, Davis, and University of Iowa.

20 Jul 2013

Risk Weighted Cumulative Exposure can measure cumulative risk of concussion in football players

Scientists at Wake Forest Baptist Medical Center have developed a new way to measure the cumulative effect of impacts to the head incurred by football players.

19 Jul 2013

Teduglutide offers relief for patients with short-bowel syndrome

A new drug, teduglutide, offers significant relief for patients with short-bowel syndrome intestinal failure who are reliant on intravenous nutrition, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

19 Jul 2013

People who exercise less likely to experience stroke, new study finds

A new study from researchers at the University of Alabama at Birmingham (UAB) is one of the first to study the relationship between exercise and stroke in a large biracial cohort of men and women in the United States. The findings are published in the American Heart Association journal Stroke.

19 Jul 2013

Study: Ultrasound waves applied to specific areas of brain appear to alter patients' moods

University of Arizona researchers have found in a recent study that ultrasound waves applied to specific areas of the brain appear able to alter patients' moods. The discovery has led the scientists to conduct further investigations with the hope that this technique could one day be used to treat conditions such as depression and anxiety.

19 Jul 2013

Healthy snacks that promote satiety may limit overall food consumption

Healthy snacks that promote a feeling of fullness (satiety) may reduce the amount of food intake at subsequent meals and limit overall food consumption, according to a presentation today at the 2013 Institute of Food Technologists (IFT) Annual Meeting & Food Expo in Chicago.

17 Jul 2013

Study demonstrates effectiveness of everolimus for TSC patients

A drug originally developed to prevent the rejection of transplanted organs has now been shown to dramatically reduce seizures in patients with tuberous sclerosis complex - a genetic disease characterized by benign tumors on multiple organ systems.

16 Jul 2013

Pair of studies sheds light on cancer cell signaling

A pair of studies by a team of University of Notre Dame researchers led by Crislyn D'Souza-Schorey, professor of biological sciences, sheds light on a biological process which is activated across a vast range of malignancies.

16 Jul 2013

Researchers develop new cry analyzer to look for clues about baby's health

To parents, a baby's cry is a signal of hunger, pain, or discomfort. But to scientists, subtle acoustic features of a cry, many of them imperceptible to the human ear, can hold important information about a baby's health.

12 Jul 2013

The number and severity of lower limb amputations have decreased in US

There have been dramatic decreases in the number and severity of lower limb amputations over the past decade, according to a new study published in the July 2013 issue of Foot & Ankle International.

12 Jul 2013

Researchers identify risk factor for maternal antibody-related autism in subset of children

Researchers with the UC Davis MIND Institute have found that prenatal exposure to specific combinations of antibodies found only in mothers of children with autism leads to changes in the brain that adversely affect behavior and development.

10 Jul 2013

Infection control program and active surveillance can reduce incidence of impatient C. diff infections

A comprehensive infection control program combined with an active surveillance process significantly reduced the incidence of Clostridium difficile (C. diff) infections in a long-term acute care hospital, according to a study published in the Journal for Healthcare Quality, the peer reviewed publication of the National Association for Healthcare Quality (NAHQ).

10 Jul 2013

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.

10 Jul 2013

Frequency News and Research

Array BioPharma announces positive results from ARRY-502 Phase 2 trial for allergic asthma

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

High arsenic levels in rice pose potential threat to human health: Study

BioCryst completes BCX4161 Phase 1 clinical trial for treatment of hereditary angioedema

Bacillus-derived Hyaluronic acid from Novozymes Biopharma, Hyasis®, increases in vitro drug release time from under 10 minutes to approximately 15 hours

Vegetation may not protect people from ozone pollution, says new research

EU-funded project examines dietary habits in people with inadequate nutrition

NKX2-8 mutation in dogs may be a risk factor for human neural tube defects, say researchers

Risk Weighted Cumulative Exposure can measure cumulative risk of concussion in football players

Teduglutide offers relief for patients with short-bowel syndrome

People who exercise less likely to experience stroke, new study finds

Study: Ultrasound waves applied to specific areas of brain appear to alter patients' moods

Healthy snacks that promote satiety may limit overall food consumption

Study demonstrates effectiveness of everolimus for TSC patients

Pair of studies sheds light on cancer cell signaling

Researchers develop new cry analyzer to look for clues about baby's health

The number and severity of lower limb amputations have decreased in US

Researchers identify risk factor for maternal antibody-related autism in subset of children

Infection control program and active surveillance can reduce incidence of impatient C. diff infections

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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