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Helen DeVos Children's Hospital wins first annual Leape Ahead Award

The American College of Physician Executives (ACPE) is pleased to announce the selection of Helen DeVos Children's Hospital as the winner of the first annual Leape Ahead Award.

20 Feb 2012

Open application marketplace for ambient assisted-living solutions

The success of Apple's App Store and the Android Market has inspired EU-funded developers of 'Ambient assisted-living' (AAL) solutions to develop their own open application marketplace and work together on interoperable platforms. In doing so, they are hoping to mainstream technology that will help older people live more active and comfortable lives.

20 Feb 2012

Massive infant Tylenol recall

Johnson & Johnson has announced the recall of its entire U.S. supply of infants' Tylenol—about 574,000 bottles—due to a design flaw. The flaw involved bottles of grape-flavoured infants' Tylenol, which had only just returned to shelves in November announced J&J last Friday.

20 Feb 2012

CAI improves asthma outcomes and saves $1.46 for every dollar spent

Nearly 1 in 10 children have asthma, according to government statistics, and in low-income parts of Boston, nearly 16 percent of children are affected. A program called the Community Asthma Initiative (CAI), developed and implemented in 2005 by clinicians at Children's Hospital Boston, demonstrates the potential to dramatically reduce hospitalization and emergency department visits for asthma -- improving patient outcomes and saving $1.46 per dollar spent through reduced hospital utilization.

20 Feb 2012

Natural compound of Chilean avocado plant can combat resistant yellow staphylococci

Aggressive infections in hospitals are an increasing health problem worldwide. The development of bacterial resistance is alarming. Now a young Danish scientist has found a natural substance in a Chilean rainforest plant that effectively supports the effect of traditional treatment with antibiotics.

20 Feb 2012

EC approves Plexxikon's Zelboraf to treat BRAF mutation-positive MM

Plexxikon Inc., a member of Daiichi Sankyo Group, today announced that the European Commission has approved Zelboraf (vemurafenib) for the monotherapy treatment of adult patients with BRAFV600 mutation-positive unresectable or metastatic melanoma.

20 Feb 2012

Indiana CTSI HUB offers open-source software to accelerate clinical and translational research

At a time when medical research increasingly requires collaboration by large numbers of busy people, the Indiana Clinical and Translational Science Institute HUB offers a model for using advanced information technology to link scientists, health providers, community partners and others for the purpose of accelerating clinical and translational research.

20 Feb 2012

Substituting smokeless tobacco products can save smokers' lives

Substituting smokeless tobacco products can save smokers' lives, and there is a scientific foundation that proves it.

20 Feb 2012

Study identifies USP15 as a critical protein in cancer

After years studying the molecular bases of glioblastoma - the most common brain tumor and one of the most aggressive of all cancers, the group led by Dr. Joan Seoane , Director of Translational Research at the Vall d'Hebron Institute of Oncology (VHIO) and ICREA Research Professor has today published a study in Nature Medicine identifying USP15 as a critical protein in cancer which, thanks to its molecular characteristics, shows enormous therapeutic promise.

20 Feb 2012

Modified imatinib cancer drug prevents morphine tolerance in rats

By reformulating the common cancer drug imatinib (Gleevec), researchers have eliminated morphine tolerance in rats - an important step toward improving the effectiveness of chronic pain management in patients, according to researchers at The University of Texas MD Anderson Cancer Center.

20 Feb 2012

ESOF 2012 science program launches today at AAAS meeting in Vancouver

The science program for Euroscience Open Forum 2012 (ESOF 2012) was officially launched today at the AAAS meeting in Vancouver.

20 Feb 2012

Symposium discusses links between genetic, epigenetic and environmental influences on autism

Two UC Davis MIND Institute researchers will lead a symposium on relationships between genetic, epigenetic and environmental influences on the development of autism in children during the American Association for the Advancement of Science (AAAS) Annual Meeting, Feb. 16 -18 in Vancouver, Canada.

20 Feb 2012

Study reveals potential strength of different anti-HIV combination drugs

Using a mathematical formula that carefully measures the degree to which HIV infection of immune system cells is stalled by antiretroviral therapy, AIDS experts at Johns Hopkins have calculated precisely how well dozens of such anti-HIV drugs work, alone or in any of 857 likely combinations, in suppressing the virus. Results of the team's latest research reveal how some combinations work better than others at impeding viral replication, and keeping the disease in check.

19 Feb 2012

Penn oncologist to discuss role of autophagy in fighting cancer at AAAS annual meeting

Blocking autophagy -- the process of "self-eating" within cells -- is turning out to be a viable way to enhance the effectiveness of a wide variety of cancer treatments.

19 Feb 2012

Clazosentan drug shows promise against TBI in rats

A new drug is showing promise in shielding against the harmful effects of traumatic brain injury (TBI) in rats, according to a study that was released today and will be presented at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012.

19 Feb 2012