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Researchers identify new principle for how epigenetic changes can occur

In a new study, researchers at Uppsala University have found evidence of a new principle for how epigenetic changes can occur. The principle is based on an enzyme, tryptase, that has epigenetic effects that cause cells to proliferate in an uncontrolled manner.

20 Jan 2017

UCF researcher combines new and old science to create method for speedy medical tests

A UCF researcher has combined cutting-edge nanoscience with a magnetic phenomenon discovered more than 170 years ago to create a method for speedy medical tests.

20 Jan 2017

Study examines differences in liver damage between binge drinkers and heavy drinkers

Alcoholic liver disease (ALD) occurs on a spectrum of severity. The majority of people who drink excessively develop a fatty liver, which though often symptom free, can progress to a state of inflammation, fibrosis, and cell death that can be fatal.

20 Jan 2017

Researchers discover how bacterial enzyme can blunt the body's key immune defenses

Scientists have discovered how a unique bacterial enzyme can blunt the body's key weapons in its fight against infection.

20 Jan 2017

‘Collateral lethality’ may create new therapeutic options for several cancers

Cancer cells often delete genes that normally suppress tumor formation. These deletions also may extend to neighboring genes, an event known as "collateral lethality," which may create new options for development of therapies for several cancers.

19 Jan 2017

OSU scientists develop new weapon to combat antibiotic-resistant germs

Oregon State University researchers have developed a new weapon in the battle against antibiotic-resistant germs - a molecule that neutralizes the bugs' ability to destroy the antibiotic.

19 Jan 2017

Research finding provides new target for regulating cell division

Modern genome sequencing methods used to measure the efficiency of synthesis of individual protein during cell division has found that the enzymes that make lipids and membranes were synthesized at much greater efficiency when a cell is ready to split.

19 Jan 2017

Researchers show how adult learning is impaired in females using mouse models of Rett syndrome

Neurodevelopmental disorders like autism very likely have their origin at the dawn of life, with the emergence of inappropriate connectivity between nerve cells in the brain.

19 Jan 2017

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

18 Jan 2017

Stem cell research offers alternative view of cancer metastasis

Stem cells are among the most energetically activated, migratory and proliferative sub-populations of tumour cells, according to observations by scholars at the Biomedical Research Centre at the University of Salford.

18 Jan 2017

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.

18 Jan 2017

Researchers identify brain cell types from cell culture of adult human neurons

Studying brain disorders in people and developing drugs to treat them has been slowed by the inability to investigate single living cells from adult patients

18 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

Using a combination of infrared spectroscopy and computer simulation, researchers at Ruhr-Universität Bochum have gained new insights into the workings of protein switches.

16 Jan 2017

OHSU research suggests avenue for developing non-addictive treatments for chronic pain

OHSU research suggests an avenue for developing treatments for chronic pain that harness the medicinal properties of cannabis while minimizing the threat of addiction.

12 Jan 2017

Researchers unravel bacterial protein structure that could pave way for new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.

12 Jan 2017

Duke researchers use cancer-seeking salmonella to treat glioblastoma

Biomedical engineers at Duke University have recruited an unlikely ally in the fight against the deadliest form of brain cancer -- a strain of salmonella that usually causes food poisoning.

11 Jan 2017

Okayama University researchers uncover potential new therapeutic target for invasive bladder cancer

Researchers at Okayama University have uncovered a potential new therapeutic target for invasive bladder cancer. The GTP hydrolysing enzyme (GTPase), called Dynamin2, facilitates the rapid invasion of cancer into surrounding tissues; inhibiting its activity could limit the progression of bladder cancer.

10 Jan 2017

Scientists gain new insights into molecular mechanisms of breast cancer development

Why does breast cancer develop and how come certain patients are resistant to established therapies? Researchers from the University of Basel have gained new insights into the molecular processes in breast tissue.

9 Jan 2017

Enzyme News and Research

Researchers identify new principle for how epigenetic changes can occur

UCF researcher combines new and old science to create method for speedy medical tests

Study examines differences in liver damage between binge drinkers and heavy drinkers

Researchers discover how bacterial enzyme can blunt the body's key immune defenses

‘Collateral lethality’ may create new therapeutic options for several cancers

OSU scientists develop new weapon to combat antibiotic-resistant germs

Research finding provides new target for regulating cell division

Researchers show how adult learning is impaired in females using mouse models of Rett syndrome

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

Stem cell research offers alternative view of cancer metastasis

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

Researchers identify brain cell types from cell culture of adult human neurons

Epigenetic changes drive successful metastases of pancreatic cancer cells

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

OHSU research suggests avenue for developing non-addictive treatments for chronic pain

Researchers unravel bacterial protein structure that could pave way for new antibiotics

Duke researchers use cancer-seeking salmonella to treat glioblastoma

Okayama University researchers uncover potential new therapeutic target for invasive bladder cancer

Scientists gain new insights into molecular mechanisms of breast cancer development

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