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Lab reports 1st instance of SARS-CoV-2 variants affecting antigen test performance

Researchers from the US recently determined the sensitivity of the Quidel Sofia SARS Antigen FIA test (Sofia 2). They found a high viral load specimen that tested negative repeatedly while using this antigen test. The study is published on the preprint server, medRxiv.

10 May 2021

New study finds a stark decrease in the number of abdominal surgeries among older adults

Many have assumed that the rates of major abdominal surgeries in adults over 65 is increasing over time as the U.S. population ages and as new technology renders surgical procedures safer for older adults.

10 May 2021

$Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk$

Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk

Hospitalized COVID-19 patients with impaired first-phase ejection fraction were nearly 5 times more likely to die compared to patients with healthier measures of this early, often undetected sign of heart failure, according to new research published today in Hypertension, an American Heart Association journal.

10 May 2021

Preclinical study finds sex differences in neurological response to SARS-CoV-2 infection

Neurological problems during and after COVID-19 are persistent and frequent. However, research is still ongoing as to why certain people exhibit specific symptoms. Research led by Yi-Ping Hsueh from the Institute of Molecular Biology in Taiwan suggests SARS-CoV-2 infection in the brain could be sex-dependent.

10 May 2021

Total COVID-19 deaths could be 7 million

A new analysis from the Institute for Health Metrics and Evaluation (IHME), which independently researches health at the University of Washington School of Medicine, shows that the total global toll due to coronavirus disease 2019 (COVID-19) could be more than twice the officially reported number of deaths, at almost 7 million.

10 May 2021

New "molecular tweezers" can help combat antibiotic-resistant bacteria

Researchers from Ben-Gurion University (BGU), together with American and German colleagues, have developed new "molecular tweezers" to combat antibiotic-resistant bacteria. Their recently announced findings were published in Cell Chemical Biology.

10 May 2021

Researchers set out overarching goals to speed up implementation of mental health research

A group of UK academics are calling for targets for mental health in order to meet the healthcare challenges of the next decade.

10 May 2021

Is COVID-19 a new disease?

In a review recently published in The Lancet Respiratory Medicine journal by Osuchowski et al. (May 6th, 2021) the currently known pathophysiology of COVID-19 is laid out to describe the mechanistic features that make COVID-19 distinct from many conditions previously thought to be similar.

9 May 2021

Researchers identify anti-inflammatory prodrug Minnelide with potential against SARS-CoV-2

Using a transgenic mouse model of COVID-19, they have observed that treatment with Minnelide reduces viral load and inflammation in the lungs and improves survival. The study is currently available on the bioRxiv* preprint server.

9 May 2021

Are infants at greater risk of COVID-19 than children?

The widely circulating SARS-CoV-2 has caused the devastating COVID-19 pandemic. The impact of this infection varies significantly with age, sparing young children for the most part, though not completely. However, a new study, released as a preprint on the medRxiv* server, shows that infants are not as resistant to the virus as children are. The researchers trace this to the expression of ACE2 to varying extents in different groups.

7 May 2021

Study suggests new avenues for treating Black patients who disproportionately die of prostate cancer

A study designed to enroll an equal number of Black and white men with advanced prostate cancer confirms key findings that have been evident in retrospective analyses and suggest potential new avenues for treating Black patients who disproportionately die of the disease.

7 May 2021

Global spread of COVID-19 has raised serious concern for patients with transthyretin amyloidosis

The global spread of COVID-19 has raised serious concern for patients with chronic disease. A correlation has been identified between the severity of COVID-19 and a patient's preexisting comorbidities.

7 May 2021

Advanced-stage kidney cancer more common in Hispanic and Native Americans in Arizona

Recently published research from the University of Arizona Health Sciences shows that advanced-stage kidney cancer is more common in Hispanic Americans and Native Americans than in non-Hispanic whites, and that both Hispanic Americans and Native Americans in Arizona have an increased risk of mortality from the disease.

6 May 2021

Aberrant immune features in healthy elderly and male subjects with severe COVID-19 may predate infection

A new study shows that the immunological features of severe COVID-19 are already present in healthy older adults and in men, before they are infected, indicating a possible explanation for this differential susceptibility towards the virus.

6 May 2021

Could stem cells improve the outcome of ARDS in severe COVID-19?

A recent study, published in Stem Cells Translational Medicine, explores the safety and efficacy of stem cells, which have been touted as the panacea for a wide range of illnesses, ranging from chronic degenerative conditions to cancer.

6 May 2021

Researchers identify potent small molecule TMPRSS2 inhibitor against SARS-CoV-2

A team of scientists from the USA and Canada has recently identified and characterized a novel small-molecule compound inhibitor of cellular serine protease TMPRSS2, which shows significant antiviral potency against emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 May 2021

Pregnancy may increase the risk of COVID-19 severity

Against the background of the COVID-19 pandemic, the impact of SARS-CoV-2 infection in pregnancy has been a subject of much controversy. In order to help answer the question as to whether this infection causes significant harm in pregnancy, a new study, released as a medRxiv* preprint, reports on the disease outcomes of this infection in pregnant women.

5 May 2021

Exposure to secondhand smoke may increase odds of developing heart failure

Breathing in secondhand cigarette smoke may leave you more vulnerable to heart failure, a condition where the heart isn't pumping as well as it should and has a hard time meeting the body's needs, according to a study being presented at the American College of Cardiology's 70th Annual Scientific Session.

5 May 2021

Stem cell therapy for COVID-19 and ARDS

In a review paper recently uploaded to the journal Biomedicine & Pharmacotherapy by Mahendiratta et al. (May 2021) the applicability of stem cells in treating severe SARS-CoV-2 infection is investigated, with regard to ARDS therapy.

5 May 2021

New vaccine candidate provides breakthrough in the fight against malaria

A malaria vaccine candidate tested on children in West Africa has shown an efficacy of around 77 per cent, say scientists, hailing it as a breakthrough in the fight against the disease.

4 May 2021

Mortality News and Research

Lab reports 1st instance of SARS-CoV-2 variants affecting antigen test performance

New study finds a stark decrease in the number of abdominal surgeries among older adults

Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk

Preclinical study finds sex differences in neurological response to SARS-CoV-2 infection

Total COVID-19 deaths could be 7 million

New "molecular tweezers" can help combat antibiotic-resistant bacteria

Researchers set out overarching goals to speed up implementation of mental health research

Is COVID-19 a new disease?

Researchers identify anti-inflammatory prodrug Minnelide with potential against SARS-CoV-2

Are infants at greater risk of COVID-19 than children?

Study suggests new avenues for treating Black patients who disproportionately die of prostate cancer

Global spread of COVID-19 has raised serious concern for patients with transthyretin amyloidosis

Advanced-stage kidney cancer more common in Hispanic and Native Americans in Arizona

Aberrant immune features in healthy elderly and male subjects with severe COVID-19 may predate infection

Could stem cells improve the outcome of ARDS in severe COVID-19?

Researchers identify potent small molecule TMPRSS2 inhibitor against SARS-CoV-2

Pregnancy may increase the risk of COVID-19 severity

Exposure to secondhand smoke may increase odds of developing heart failure

Stem cell therapy for COVID-19 and ARDS

New vaccine candidate provides breakthrough in the fight against malaria

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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