Liver News and Research

RSS

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

Patients with Middle East Respiratory Syndrome (MERS) develop more severe critical illness and have higher mortality than patients with non-MERS severe acute respiratory infection (SARI), according to investigators involved with the largest study of critically ill patients with MERS.

19 May 2016

New lab blood test may help identify HELLP syndrome in pregnant women

A laboratory blood test developed at Johns Hopkins for the diagnosis of a rare genetic red blood cell disorder also shows promise in identifying HELLP syndrome, a life-threatening high blood pressure condition affecting 1 percent of all pregnant women that causes hypertension along with end organ damage, researchers report in the May issue of the journal Experimental Hematology.

19 May 2016

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

For the first time, researchers were able to demonstrate that children diagnosed with sickle cell disease showed improvement in lung function after treatment with hydroxyurea, a treatment that is underused despite its demonstrated benefits.

19 May 2016

Research sheds light on potential impact of HCV treatment in preventing virus transmission

An international team of researchers has shed light on the potential impact of new drugs for hepatitis C virus (HCV).

19 May 2016

High levels of secretin hormone may play vital role in management of chronic liver diseases

High levels of a digestive hormone called secretin may play an important role in the management of certain chronic liver diseases, according to new research published in the journal Hepatology. These findings could result in new ways to treat cholestatic liver diseases, a condition that impairs the movement of bile, the fluid produced by the liver to digest fats.

18 May 2016

Boehringer Ingelheim presents new data on OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF)

New analyses presented at the American Thoracic Society’s 2016 annual conference (ATS 2016) further add to the efficacy and safety profile of OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF).

16 May 2016

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models.

13 May 2016

Clinical study shows sitagliptin drug not effective in treating NAFLD

A diabetes medication described in some studies as an effective treatment for nonalcoholic fatty liver disease (NAFLD) works no better than a placebo, report researchers at University of California San Diego School of Medicine, after conducting the first randomized, double-blind, controlled clinical trial of sitagliptin, an oral antihyperglycemic marketed by Merck & Co. under the name Januvia.

13 May 2016

Could oral supplements affect teenage behavior? An interview with Prof. Stein and Dr Tammam

We wanted to see whether supplementing the diet of disadvantaged adolescents with the omega 3 polyunsaturated acids, EPA & DHA, vitamins and minerals over a school term might improve their antisocial behaviour, which usually gets worse during a term.

12 May 2016

Computerized decision support tool can assist physicians in prescribing stroke prevention therapy

Physician-researchers in the College of Medicine at the University of Cincinnati have developed a computerized decision support tool that uses a combination of patient information and characteristics to assist physicians and patients with decisions about blood thinning treatment to prevent strokes in individuals with atrial fibrillation.

12 May 2016

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Two patients with melanoma that had spread to the liver survived for at least 8.5 and 12 years after resection of the hepatic tumor and treatment with patient-specific immunotherapeutic vaccines.

11 May 2016

New study sheds more light on level of alcohol consumption among people with hepatitis C

Drinking alcohol can increase the risk of illness and death from the hepatitis C virus. A new national household study of U.S. adults published in the American Journal of Preventive Medicine shows that many people living with hepatitis C report either former or current excessive alcohol use.

11 May 2016

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

A recent study reported in the May issue of the Journal of Nuclear Medicine demonstrates that Ga-68 DOTATATE PET/CT scans are superior to In-111 pentetreotide scans, the current imaging standard in the United States for detecting neuroendocrine tumors, and could significantly impact treatment management.

10 May 2016

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

The Medical University of South Carolina's Hollings Cancer Center received an $8.9 million grant from the National Cancer Institute designed to foster collaboration across clinical and laboratory research for the study of signaling in sphingolipids, a class of lipids known to be involved in the growth of solid tumor cancers.

10 May 2016

Experimental vaccine protects healthy U.S. adults from malaria infection for more than one year

An experimental malaria vaccine protected a small number of healthy, malaria-naïve adults in the United States from infection for more than one year after immunization, according to results from a Phase 1 trial described in the May 9th issue of Nature Medicine.

10 May 2016

Food deprivation may help treat fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung and the Deutsches Krebsforschungszentrum they were able to show that upon deprivation of food a certain protein is produced that adjusts the metabolism in the liver.

9 May 2016

High-level quantum chemical computations help unravel underlying mechanism of hepatocellular toxicity

Balasubramanian and Basak have recently reported quantum chemical computations that enhance our understanding of mechanisms for the causes of liver toxicity. Hepatocellular carcinoma is one of the most common forms of cancer, and the primary cause has been attributed to liver fibrosis by chemical toxins, which is followed by liver cirrhosis.

9 May 2016

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite effects on red blood cell production, treating animals with minihepcidin helps to restore normal levels of red blood cells and reduces spleen enlargement. It also controls the accumulation of excess levels of iron in beta-thalassemia that often causes severe toxic effects.

9 May 2016

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

A tension-sensitive "fail safe" protein helps make sure that when our cells divide the two resulting cells inherit the normal number of chromosomes, researchers from the University of Washington and the Fred Hutchinson Cancer Research Center report today, May 5, in the journal Cell.

6 May 2016

Unlocking cellular trap door may help in finding cures for many diseases

A team of researchers who two years ago announced a "Trojan horse" method of entering a cell without harming it have now found, in effect, the lock to the cellular "trap door."

6 May 2016

Liver News and Research

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

New lab blood test may help identify HELLP syndrome in pregnant women

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

Research sheds light on potential impact of HCV treatment in preventing virus transmission

High levels of secretin hormone may play vital role in management of chronic liver diseases

Boehringer Ingelheim presents new data on OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF)

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Clinical study shows sitagliptin drug not effective in treating NAFLD

Could oral supplements affect teenage behavior? An interview with Prof. Stein and Dr Tammam

Computerized decision support tool can assist physicians in prescribing stroke prevention therapy

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

New study sheds more light on level of alcohol consumption among people with hepatitis C

Ga-68 DOTATATE PET/CT scans more effective than current imaging standard for detecting NETS

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

Experimental vaccine protects healthy U.S. adults from malaria infection for more than one year

Food deprivation may help treat fatty liver disease

High-level quantum chemical computations help unravel underlying mechanism of hepatocellular toxicity

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

Unlocking cellular trap door may help in finding cures for many diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News