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Gilead Sciences fourth quarter total revenues increase 18% to $2.59 billion

Gilead Sciences, Inc. announced today its results of operations for the fourth quarter and full year 2012.

5 Feb 2013

Agilent launches new application compendiums on designer drug testing and toxicology of oral fluids

Agilent Technologies Inc. today introduced new application compendiums on designer drug testing and toxicology of oral fluids.

5 Feb 2013

Breast cancer genes modify age at menopause

Women with the BRCA1 or BRCA2 mutation begin menopause at a significantly younger median age than noncarriers, US researchers warn.

4 Feb 2013

Gum infections may increase risk for community-acquired pneumonia

People with moderate-to-severe periodontitis are at increased risk for community-acquired pneumonia compared with those with healthy gums, show study findings.

4 Feb 2013

Oral toxicity is frequent limitation of mTOR therapy

Oral mucositis is a frequent complication in patients taking mTOR inhibitors and a major reason for dose reductions and discontinuations in clinical trials, according to a review of this class of cancer drugs.

4 Feb 2013

Nicotine metabolism inversely linked to addiction severity in teens

Reduced nicotine metabolism is associated with a greater number of cigarettes smoked per day and increased levels of dependence in adolescent smokers, researchers report.

4 Feb 2013

Common mouthwash advice ‘not evidence-based’

People with fixed dental appliances use fluoride-containing mouthrinses less often than is optimal to prevent the development of white spot lesions, researchers have found.

4 Feb 2013

Identification of progenitors may help treat clinical taste dysfunction

Scientists at the Monell Center have identified the location and certain genetic characteristics of taste stem cells on the tongue. The findings will facilitate techniques to grow and manipulate new functional taste cells for both clinical and research purposes.

4 Feb 2013

Scientists report first generation of hiPSCs from patients with maturity onset diabetes of the young

Joslin scientists report the first generation of human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes of the young (MODY). These cells offer a powerful resource for studying the role of genetic factors in the development of MODY and testing potential treatments.

2 Feb 2013

Book reviews psilocybin's potential in alleviating psychological distress in cancer patients

Improvements in the diagnosis and treatment of cancers in recent years have led to a marked increase in patients' physical survival rates. While doctors can treat the physical disease, what is not well understood is how best to address the psychological needs of patients with cancer.

1 Feb 2013

Merck full-year 2012 worldwide sales decrease 2% to $47.3 billion

Merck, known as MSD outside the United States and Canada, today announced financial results for the fourth quarter and full year of 2012.

1 Feb 2013

Positive results from PaxVax's Ad4-H5-Vtn vector vaccine Phase 1 trial on avian flu

PaxVax, Inc., which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced positive results in a Phase 1 clinical trial for its oral, replicating adenovirus serotype 4 (Ad4) vector vaccine for H5N1 (avian flu).

31 Jan 2013

C. albicans capable of sexual reproduction

Like many fungi and one-celled organisms, Candida albicans, a normally harmless microbe that can turn deadly, has long been thought to reproduce without sexual mating. But a new study by Professor Judith Berman and colleagues at the University of Minnesota and Tel Aviv University shows that C. albicans is capable of sexual reproduction.

31 Jan 2013

GSU associate professor receives federal grant to bolster flu vaccine research

Sang-Moo Kang, associate professor at Georgia State University's Center for Inflammation, Immunity and Infection, has received a federal five-year, $3.4 million grant to bolster research that will lead to better flu vaccines and vaccines against respiratory syncytial virus (RSV), a disease for which there is no immunization.

31 Jan 2013

Kemwell Biopharma’s Oral Solids manufacturing facility completes USFDA inspection

Kemwell Biopharma Pvt. Ltd., a global pharmaceutical contract development and manufacturing company, announced today that its Oral Solids manufacturing facility located in Bangalore, India has successfully completed a U.S. Food and Drug Administration (USFDA) inspection.

31 Jan 2013

Top ten tips for keeping bed bugs at bay

Bed bugs are on the rise and $1,000 per day ordinances are being suggested in cities like Chicago to enforce combat of the pests. "Know thy enemy," says Jorge Parada, MD, medical director, infection control, Loyola University Health System. "There are lots of myths out there about bed bugs and people may be getting caught up over nothing."

30 Jan 2013

Low-income and minority parents/guardians receptive toward vaccinating boys against HPV

A new Boston University School of Medicine (BUSM) study has found that low-income and minority parents/guardians were receptive toward vaccinating boys against Human Papilloma Virus (HPV). However, racial/ethnic differences emerged in attitudes regarding school-entry mandates. The findings appear online in the journal Clinical Pediatrics.

30 Jan 2013

Tofacitinib fights rheumatoid arthritis progression

Tofacitinib treats symptoms and prevents structural damage in patients with rheumatoid arthritis who do not respond well to methotrexate, indicate phase III trial findings.

29 Jan 2013

Janssen, Medivir and Idenix partner for clinical development of HCV combination therapy

Medivir AB today announced a non-exclusive collaboration between Janssen Pharmaceuticals Inc. (Janssen) and Idenix Pharmaceuticals for the clinical development of an all-oral (interferon-free) direct-acting antiviral (DAA) hepatitis C (HCV) combination therapy.

29 Jan 2013

Researchers investigate acidity in solid tumors to determine if pH levels play a role in cell invasion

Researchers at Moffitt Cancer Center and colleagues at Wayne State University School of Medicine investigated the acidity in solid tumors to determine if pH levels play a role in cancer cell invasion in surrounding tissues.

28 Jan 2013

Oral News and Research

Gilead Sciences fourth quarter total revenues increase 18% to $2.59 billion

Agilent launches new application compendiums on designer drug testing and toxicology of oral fluids

Breast cancer genes modify age at menopause

Gum infections may increase risk for community-acquired pneumonia

Oral toxicity is frequent limitation of mTOR therapy

Nicotine metabolism inversely linked to addiction severity in teens

Common mouthwash advice ‘not evidence-based’

Identification of progenitors may help treat clinical taste dysfunction

Scientists report first generation of hiPSCs from patients with maturity onset diabetes of the young

Book reviews psilocybin's potential in alleviating psychological distress in cancer patients

Merck full-year 2012 worldwide sales decrease 2% to $47.3 billion

Positive results from PaxVax's Ad4-H5-Vtn vector vaccine Phase 1 trial on avian flu

C. albicans capable of sexual reproduction

GSU associate professor receives federal grant to bolster flu vaccine research

Kemwell Biopharma’s Oral Solids manufacturing facility completes USFDA inspection

Top ten tips for keeping bed bugs at bay

Low-income and minority parents/guardians receptive toward vaccinating boys against HPV

Tofacitinib fights rheumatoid arthritis progression

Janssen, Medivir and Idenix partner for clinical development of HCV combination therapy

Researchers investigate acidity in solid tumors to determine if pH levels play a role in cell invasion

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