Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Study: Hedgehog cell signaling pathway may play role in breast cancer metastasis

Molecules called long non-coding RNAs (lncRNAs) have been implicated in breast cancer but exactly why they cause metastasis and tumor growth has been little understood…until now.

14 Nov 2014

UCSD researchers describe surprising role of protein in embryonic development

Hematopoietic stem cells (HSCs) give rise to all blood and immune cells throughout the life of vertebrate organisms, from zebrafish to humans. But details of their genesis remain elusive, hindering efforts to develop induced pluripotent stem cell (iPSC) replacements that might address a host of blood disorders.

7 Nov 2014

Researchers develop mouse model that reproduces most typical features of Noonan syndrome

Noonan syndrome is a rare disease that is characterised by a set of pathologies, including heart, facial and skeletal alterations, pulmonary stenosis, short stature, and a greater incidence of haematological problems (mainly juvenile myeloid leukaemia, or childhood leukaemia).

6 Nov 2014

Melbourne researchers reveal key steps involved in programmed cell death

Melbourne researchers have uncovered key steps involved in programmed cell death, offering new targets for the treatment of diseases including lupus, cancers and neurodegenerative diseases.

31 Oct 2014

New international consortium to advance GPCR research for drug development

The generation of high-resolution pictures of hundreds of medically important proteins known as G-protein coupled receptors (GPCRs) will be the goal of an ambitious new international partnership. Called the GPCR Consortium, this non-profit initiative brings together major pharmaceutical companies and leading research institutes from three continents to advance GPCR research for drug development.

29 Oct 2014

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Scientists say they have identified in about 20 percent of colorectal and endometrial cancers a genetic mutation that had been overlooked in recent large, comprehensive gene searches. With this discovery, the altered gene, called RNF43, now ranks as one of the most common mutations in the two cancer types.

27 Oct 2014

Treeway, LACDR join forces to optimize clinical trial designs, data-analysis for ALS

Treeway and LACDR at the University of Leiden join forces and form a collaboration focused on the optimization of clinical trial designs and data-analysis for ALS (Amyotrophic Lateral Sclerosis) through the use of population disease progression models.

16 Oct 2014

Power grid failure inside injured cardiac cells triggers post-heart attack arrhythmias

Heart attack survivors often experience dangerous heart rhythm disturbances during treatment designed to restore blood flow to the injured heart muscle, a common and confounding complication of an otherwise lifesaving intervention.

9 Oct 2014

Anti-inflammatory treatment may prevent heterotopic ossification

An anti-inflammatory treatment, studied in the labs of regenerative medicine specialists and trauma surgeons, may prevent what's become one of the war-defining injuries for today's troops.

26 Sep 2014

Researchers discover key cell-signaling pathway that contributes to development of Alzheimer's disease

Researchers at Jacksonville's campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer's disease patients as well as loss of communication between neurons - both significant contributors to this type of dementia.

21 Sep 2014

Researchers reveal importance of highly specialised immune cells in killing melanoma cells

Melbourne researchers have revealed the critical importance of highly specialised immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs.

14 Aug 2014

Scientists use nanowires to monitor and influence cellular activity

No longer just fantastical fodder for sci-fi buffs, cyborg technology is bringing us tangible progress toward real-life electronic skin, prosthetics and ultraflexible circuits.

12 Aug 2014

Bio-Techne revenue increases 16% to $92.5 million in fourth quarter 2014

Techne Corporation, (d/b/a Bio-Techne) today reported its financial results for the fourth quarter and full year ended June 30, 2014.

From ProteinSimple 11 Aug 2014

Drug used for treating rheumatoid arthritis can improve health of kidney transplant recipients

UC San Francisco is the lead institution on a new seven-year, $17 million multicenter study funded by the National Institutes of Health to determine if certain immune system cells and/or a drug now used for treating rheumatoid arthritis can be effective in improving and maintaining the long-term health of kidney transplant recipients.

5 Aug 2014

Researchers identify possible new drug target for treating childhood blood cancer

In what is believed to be the largest genetic analysis of what triggers and propels progression of tumor growth in a common childhood blood cancer, researchers at NYU Langone Medical Center report that they have identified a possible new drug target for treating the disease.

1 Aug 2014

UT Southwestern researcher named recipient of ASBMB Merck Award for research on molecular biology

Dr. Zhijian "James" Chen, Professor of Molecular Biology and a Howard Hughes Medical Institute investigator at UT Southwestern Medical Center, has been named the 2015 recipient of the American Society for Biochemistry and Molecular Biology Merck Award, which recognizes outstanding contributions to research in biochemistry and molecular biology.

18 Jul 2014

Cell Signaling News and Research

Further Reading

Study: Hedgehog cell signaling pathway may play role in breast cancer metastasis

UCSD researchers describe surprising role of protein in embryonic development

Researchers develop mouse model that reproduces most typical features of Noonan syndrome

Melbourne researchers reveal key steps involved in programmed cell death

New international consortium to advance GPCR research for drug development

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Treeway, LACDR join forces to optimize clinical trial designs, data-analysis for ALS

Power grid failure inside injured cardiac cells triggers post-heart attack arrhythmias

Anti-inflammatory treatment may prevent heterotopic ossification

Researchers discover key cell-signaling pathway that contributes to development of Alzheimer's disease

Researchers reveal importance of highly specialised immune cells in killing melanoma cells

Scientists use nanowires to monitor and influence cellular activity

Bio-Techne revenue increases 16% to $92.5 million in fourth quarter 2014

Drug used for treating rheumatoid arthritis can improve health of kidney transplant recipients

Researchers identify possible new drug target for treating childhood blood cancer

UT Southwestern researcher named recipient of ASBMB Merck Award for research on molecular biology

Researchers devise new method for extracting molecules from live cells

Scientists show how cannabis could reduce tumor growth in cancer patients

New knowledge may expand treatments for patients with lung cancer

TCGA finds novel mutations in key cancer-causing pathway in lung adenocarcinoma

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Expanding access to NMR with the Fourier 80 Duo