Low Density Lipoprotein (LDL) News and Research

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HDL cholesterol can transform from good to bad actor in heart-disease process

We've all heard about the importance of raising HDL, or the so-called "good" cholesterol, and lowering LDL, or "bad" cholesterol, to improve heart health. While we've come to assume HDL cholesterol is an inherently good thing, a new study shows that for a certain group of patients, this is not always the case. The study is the first to find that a high level of the supposedly good cholesterol places a subgroup of patients at high risk for recurrent coronary events, such as chest pain, heart attack, and death.

26 May 2010

Researchers analyze impact of health promotion program on cardiovascular disease-related medical, hospital costs

A comprehensive health promotion program reduced cardiovascular disease-related medical and hospital costs, according to a new study. CSX Transportation, a national company with 30,000 employees, developed the program in 2004 to address employees' high rates of cardiovascular disease when compared to national benchmarks and the associated higher healthcare costs.

21 May 2010

Blood biomarker underscores role of inflammation in vascular disease

UC Davis researchers have discovered that a blood component linked with inflammation can predict coronary artery disease in African-Americans.

21 May 2010

AMT reports positive preclinical data from cholesterol targeting AAV gene therapy study

Amsterdam Molecular Therapeutics a world leader in gene therapy, today reported positive preclinical data from a study using an AAV gene therapy product to lower cholesterol.

21 May 2010

Pistachio nuts increase levels of antioxidants in blood of adults with high cholesterol: Researchers

Pistachio nuts, eaten as part of a healthy diet, can increase the levels of antioxidants in the blood of adults with high cholesterol, according to an international team of nutritional scientists.

20 May 2010

Elevated levels of Lp-PLA2 associated with increased risk of coronary heart disease

A meta-analysis of approximately 80,000 individuals from 32 prospective studies was published in The Lancet on May 1, 2010. The data shows that elevated levels of lipoprotein-associated phospholipase A2 (Lp-PLA2), a vascular-specific inflammatory enzyme, are associated with an increased risk of coronary heart disease similar in magnitude to that with non-HDL cholesterol or systolic blood pressure.

20 May 2010

Regular consumption of pistachios lowers risk of CHD: Study

A new nut and blood lipid study published on May 10, 2010, in Archives of Internal Medicine, led by Dr. Joan Sabate and colleagues at Loma Linda University (Loma Linda, Calif.), confirms that eating nuts, like pistachios, have a total and LDL (bad)-cholesterol-lowering effect, supporting the evidence that regular nut consumption can lower the risk of coronary heart disease.

18 May 2010

Individual's lifestyle choices can affect cholesterol, triglycerides levels: Mayo Clinic Health Letter

Diet and lifestyle choices aren't only evident on the bathroom scale. The effect of these choices is also reflected with relative accuracy in cholesterol numbers.

13 May 2010

Atherotech to showcase VAP Cholesterol Test at NLA Scientific Sessions 2010

Atherotech Inc. will exhibit its VAP® Cholesterol Test in booth #102 at the National Lipid Association (NLA) Scientific Sessions 2010. The meeting takes place May 13-16 at the Sheraton Hotel and Towers in Chicago.

13 May 2010

Regeneron Pharmaceuticals provides update on REGN727, REGN475 antibody product candidates

Regeneron Pharmaceuticals, Inc. (REGN) provided an update on two antibody product candidates in its pipeline and scheduled its first Investor Day to be held in New York City on July 15, 2010. Both product candidates, REGN727 (SAR236553) and, REGN475 (SAR164877) are being developed with sanofi-aventis under a global, strategic collaboration to discover, develop, and commercialize fully human antibodies.

13 May 2010

Wheat aleurone contains high levels of potentially healthpromoting compounds

Wheat aleurone is a novel wheat grain fraction with high levels of potentially healthpromoting compounds. New clinical trials with ready-to-eat cereals and bread containing wheat aleurone have been performed, and showed increased blood concentrations of tentatively beneficial compounds such as betaine, and decreased homocysteine and LDL-cholesterol which are both associated with heart disease risk.

12 May 2010

Chocolate, coffee and red wine may not benefit the heart: Study

Heart Foundation revealed in a recent review of over 100 studies over the last decade that claims of chocolates, red wine and coffee that are supposedly loaded with antioxidants that do good to the heart are unreliable.

11 May 2010

Nuts can reduce blood cholesterol levels: Study

Consuming more nuts appears to be associated with improvements in blood cholesterol levels, according to a pooled analysis of data from 25 trials reported in the May 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

11 May 2010

Nuts added to unhealthy diets can still reduce cholesterol and benefit the heart

It has been known for a while now that eating nuts regularly offers cardiovascular benefits. Now a new study has established the fact that a regular intake of nuts can lead to better and healthier cholesterol levels.

10 May 2010

Swedish researchers present a new principle for inhibiting atherosclerosis

7 May 2010

Genzyme to initiate $2 billion stock buyback

Genzyme Corp. today announced that its Board of Directors has voted to pursue several actions to increase shareholder value. The company will initiate a $2 billion stock buyback, under which $1 billion of stock will be repurchased in the near term and financed with debt. The additional $1 billion of stock will be repurchased during the next 12 months.

7 May 2010

Research reveals reason for ineffectiveness of antioxidants against cardiovascular disease

A new study by researchers at the Swedish medical university Karolinska Institutet shows that the immune defence's T cells can attack the "bad" LDL cholesterol and thereby cause an inflammation that leads to atherosclerosis. By producing a vaccine against the T cell receptors, the researchers have managed to inhibit the development of atherosclerosis in animals.

6 May 2010

Enzyme technology developed to improve quality, safety and nutritional attributes of oat based foods

Oats is a highly nutritious cereal, which can be tolerated by large number of celiac patients. A range of commercial oat flours as well as specific oat flours produced from single varieties have been evaluated for their suitability for bread-baking. Enzyme technology, bioprocessing as well as high-pressure processing technology have been successfully applied to improve the quality, safety and nutritional attributes of oat based foods.

5 May 2010

Belatacept preserves kidney function in transplant recipients better than cyclosporine, says study

Two-year results from phase III clinical trials show the experimental immunosuppressive drug belatacept can better preserve kidney function in kidney transplant recipients while preventing graft rejection when compared with the standard immunosuppressive drug cyclosporine.

3 May 2010

Some parts of cholesterol testing for children can be performed without fasting: Study

Physicians usually ask children to fast overnight before a cholesterol test. New research shows that this may not always be necessary.

3 May 2010

Low Density Lipoprotein (LDL) News and Research

HDL cholesterol can transform from good to bad actor in heart-disease process

Researchers analyze impact of health promotion program on cardiovascular disease-related medical, hospital costs

Blood biomarker underscores role of inflammation in vascular disease

AMT reports positive preclinical data from cholesterol targeting AAV gene therapy study

Pistachio nuts increase levels of antioxidants in blood of adults with high cholesterol: Researchers

Elevated levels of Lp-PLA2 associated with increased risk of coronary heart disease

Regular consumption of pistachios lowers risk of CHD: Study

Individual's lifestyle choices can affect cholesterol, triglycerides levels: Mayo Clinic Health Letter

Atherotech to showcase VAP Cholesterol Test at NLA Scientific Sessions 2010

Regeneron Pharmaceuticals provides update on REGN727, REGN475 antibody product candidates

Wheat aleurone contains high levels of potentially healthpromoting compounds

Chocolate, coffee and red wine may not benefit the heart: Study

Nuts can reduce blood cholesterol levels: Study

Nuts added to unhealthy diets can still reduce cholesterol and benefit the heart

Swedish researchers present a new principle for inhibiting atherosclerosis

Genzyme to initiate $2 billion stock buyback

Research reveals reason for ineffectiveness of antioxidants against cardiovascular disease

Enzyme technology developed to improve quality, safety and nutritional attributes of oat based foods

Belatacept preserves kidney function in transplant recipients better than cyclosporine, says study

Some parts of cholesterol testing for children can be performed without fasting: Study

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