Movement disorders News and Research

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Prana Biotechnology has discovered novel drug candidates for use in Parkinson's disease

Prana Biotechnology Limited has announced that it has identified novel therapeutic drug candidates from its Parkinson's disease program. Already, a lead candidate drug has demonstrated positive effects in pre-clinical studies, protecting the brain from damage to the substantia nigra, the area of the brain affected in Parkinson's disease.

6 May 2008

Botulinum toxin is safe and effective for treating cervical dystonia

New guidelines developed by the American Academy of Neurology confirm that the drug botulinum toxin is safe and effective for treating cervical dystonia, a condition of involuntary head tilt or neck movement, spasticity and other forms of muscle overactivity that interfere with movement in adults and children with an upper motor neuron syndrome, and excessive sweating of the armpits and hands.

5 May 2008

Deep brain stimulation may help people with treatment resistant major depression

Researchers from the Cleveland Clinic, Brown University, and Massachusetts General Hospital will present results of a long-term outcome study that builds on previous promising research, which has shown that deep brain stimulation (DBS) is a potentially effective treatment option for people with treatment resistant major depression.

29 Apr 2008

Cholesterol in Parkinson's disease

In 2006, University of North Carolina at Chapel Hill researchers published a study that found people with low levels of LDL cholesterol are more likely to have Parkinson's disease than people with high LDL levels.

7 Apr 2008

URMC testing new device for Parkinson's

The University of Rochester Medical Center (URMC) is one of a handful of sites nationwide testing a new device for patients with Parkinson's disease and essential tremor, a neurological movement disorder.

14 Feb 2008

Deep brain stimulation may improve memory

Deep brain stimulation (DBS) surgery, which is used to treat Parkinson's disease and other movement disorders, is now being studied for its potential to treat a variety of conditions.

4 Feb 2008

Trichloroethylene exposure linked to Parkinsonism

Industrial workers who worked with trichloroethylene (TCE) may face a greater risk for parkinsonism, a study by a team of University of Kentucky researchers shows.

10 Jan 2008

Trichloroethylene chemical - widely used in industry - is a risk factor for parkinsonism

Parkinson's disease, the most common neurodegenerative movement disorder caused by aging, can also be caused by pesticides and other neurotoxins.

8 Jan 2008

Researchers establish risk factors for Parkinson's disease

Doctors know an impaired sense of smell is an early indicator of Parkinson's Disease.

8 Jan 2008

Lower frequency deep brain stimulation effective treatment for dystonia

A Mount Sinai Medical Center study has found that lower frequency deep brain stimulation in young patients with primary torsion dystonia is as effective as higher frequency stimulation, which has been commonly used.

25 Oct 2007

Researchers report most complete list so far of the proteins present in the cerebral cortex

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics the most complete list so far of the proteins present in the cerebral cortex – the outermost layer of the brain that plays a central role in memory, language, cognition, and consciousness.

8 Oct 2007

Ovary removal before menopause leads to memory and movement problems

Women who have their ovaries removed before menopause are at an increased risk of developing memory problems or dementia and movement disorders such as Parkinson's disease, according to two studies published August 29, 2007, in the online edition of Neurology, the medical journal of the American Academy of Neurology.

30 Aug 2007

Researchers use 'genomic pathway' to predict Parkinson's

A new Mayo Clinic study provides strong evidence that the joint effects of common DNA variations in several genes that encode proteins within a well-defined biological pathway largely explain why some persons get Parkinson's disease while others don't, and even predict with great accuracy at what age people might develop their first symptoms.

17 Jun 2007

Myelin and Huntington's disease

Last month, Dr. George Bartzokis, director of the UCLA Memory Disorders and Alzheimer's Disease Clinic, suggested in the journal Alzheimer's & Dementia that the breakdown of a type of myelin that develops late in life promotes the buildup of toxic amyloid plaques long associated with Alzheimer's disease.

14 Jun 2007