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Deep brain stimulation improves memory and promotes neuron growth in Rett mice

A recent study from the lab of Dr. Jianrong Tang, associate professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital shows that deep brain stimulation (DBS) of a specific brain region results in a significant and sustained improvement of memory in Rett mice.

13 Oct 2023

Study sheds light on how traumatic memories are created

Scientists have long speculated about the physical changes that occur in the brain when a new memory is formed. Now, research from the National Institute for Physiological Sciences (NIPS) has shed light on this intriguing neurological mystery.

12 Oct 2023

New drug molecule restores lost nerve-muscle connections, enhances strength

A small molecule previously shown to enhance strength in injured or old laboratory mice does so by restoring lost connections between nerves and muscle fibers, Stanford Medicine researchers have found.

11 Oct 2023

Fragile X syndrome may be unfolding in brain cells even before birth

Fragile X syndrome, the most common form of inherited intellectual disability, may be unfolding in brain cells even before birth, despite typically going undiagnosed until age 3 or later.

10 Oct 2023

3D printing crafts cerebral cortex tissues: A breakthrough for brain injury treatment

Researchers utilize 3D printing to craft cerebral cortex tissues with organized neurons, offering potential treatments for brain injuries. This novel technique prints neural progenitors in layer-by-layer sequences, aiming for accurate tissue restoration in damaged brains.

8 Oct 2023

Study helps explain how the brain adapts during a critical period of adulthood

Developing brains become shaped by the sights, sounds, and experiences of early life. The brain's circuits grow more stable as we age.

5 Oct 2023

CRISPR gene editing study provides insights into how autism gene affects brain development

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

5 Oct 2023

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Researchers developed the ATRIVIEW® platform to screen for molecules that promote differentiation neural stem cells (NSCs).

4 Oct 2023

Brain activity changes depending on context, even when performing the same action

Standing at a crosswalk, the signal changes from "don't walk," to "walk." You might step out into the street straight away, or you might look both ways before you cross.

3 Oct 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

Stanford researchers uncover the science behind that 'tight skin' feeling

Researchers quantitatively investigated the mechanisms by which topical treatments modulate skin sensory perceptions, linking biomechanical changes in the skin to activation of cutaneous mechanoreceptors and subsequent neural signaling and correlating these changes to subjective sensory experiences reported by individuals.

29 Sep 2023

Scientists bridge gap in understanding how the brain recognizes familiar objects

Because figuring out what is new and what is familiar in what we see is such a critically important ability for prioritizing our attention, neuroscientists have spent decades trying to figure out how our brains are typically so good at it.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Protein p53 is linked directly to autism-like behavior, study shows

Researchers have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and psychiatric disorders like autism spectrum disorder.

27 Sep 2023

Study reveals neurological mechanism behind the perception of skin tightness

When we wash our face with a cleanser, our skin can start to feel tight. With the application of a favorite moisturizer, that feeling often goes away.

26 Sep 2023

How cleansers and moisturizers make your skin feel tight or soft

Some cleansers make the skin feel "tight" and some moisturizers make the skin feel "soft." Reinhold H. Dauskardt and colleagues traced the mechanisms by which applying cleansers or moisturizers to the skin results in such sensations, using in-vitro biomechanical testing, computational neural stimulation modeling, and self-assessment surveys completed by thousands of participants.

26 Sep 2023

Multipronged gene therapy restores walking in mice after complete spinal cord injury

When the spinal cords of mice and humans are partially damaged, the initial paralysis is followed by the extensive, spontaneous recovery of motor function.

21 Sep 2023

Ongoing gene therapy trials have driven increased use of ALS genetic testing, finds study

Researchers at The Ohio State University Wexner Medical Center and College of Medicine led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.

19 Sep 2023

Gaining new insights into neurological diseases by studying circular RNAs in brain cells

Researchers are gaining new insights into neurological diseases by studying circular RNAs (circRNAs) in brain cells.