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Scientists find new drug target to improve cardiac output in heart failure patients

Researchers led by Julian E. Stelzer, PhD, associate professor in the department of physiology and biophysics at Case Western Reserve University School of Medicine, have found a new target for drug developers seeking straightforward ways to improve cardiac output in heart failure patients.

4 Apr 2017

Researchers identify mechanism to recover aging of Progeria patients

DGIST's research team has identified a mechanism that can recover the aging of patients with Hutchinson-Gilford Progeria Syndrome. DGIST announced that the Chair Professor Park SangChul of New Biology and the research team led by Professor Lee YoungSam has discovered a drug that can improve the aging of HGPS patients and identified the mechanism of aging recovery by using the drug.

4 Apr 2017

Researchers show how cellular stress regulates production of hemoglobin

Our ability to breathe oxygen is critical to our survival. This process is mediated by the hemoglobin in our blood, which carries oxygen. Since air contains less oxygen on high mountains, the body is under pressure to make hemoglobin rapidly -- a stressful time.

4 Apr 2017

Researchers discover key to reveal secret of reversible aging recovery

DGIST's research team discovered substances that can induce reversible aging* recovery and identified an aging recovery mechanism using these substances.

3 Apr 2017

Researchers shed light on diverse effects of exercise on individuals

In Japan, due to the changes of lifestyle such as less physical activities than before, more and more people suffer from the lifestyle diseases like metabolic syndromes, type-2 diabetes and hypertension.

28 Mar 2017

Rogue proteins involved in breast cancer point to potential treatment options

For patients with difficult-to-treat cancers, doctors increasingly rely on genomic testing of tumors to identify errors in the DNA that indicate a tumor can be targeted by existing therapies.

28 Mar 2017

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Huntington's disease is a neurodegenerative disorder that causes patients to lose their ability to move, speak, and even think. It is caused by a gene mutation that produces an abnormal form of the protein huntingtin, which aggregates and builds up inside neurons of the cortex and striatum.

23 Mar 2017

Simple blood test may soon eliminate need for invasive procedures to detect, monitor cancer

Doctors may soon be able to detect and monitor a patient's cancer with a simple blood test, reducing or eliminating the need for more invasive procedures, according to Purdue University research.

21 Mar 2017

Research findings point to new strategies for tapping into plant energy to produce biofuels, biomaterials

Even plants have to live on an energy budget. While they're known for converting solar energy into chemical energy in the form of sugars, plants have sophisticated biochemical mechanisms for regulating how they spend that energy. Making oils costs a lot.

17 Mar 2017

Octapharma uses G:BOX Chemi XX6 imager to accurately characterise large therapeutic proteins

Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce its G:BOX Chemi XX6 multi-application-functional imager is being utilised by scientists at major human protein R&D company, Octapharma Biopharmaceuticals GmbH in Germany for analysing a range of large proteins.

From Syngene 17 Mar 2017

Study reports global quantitative interactomics analysis of protein phosphatome

Coordinated activities of protein kinases and protein phosphatases ensure phosphorylation homeostasis and amplitude of signaling response, and understandably its imbalance is linked to diseases, such as cancer.

16 Mar 2017

Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer

Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

24 Feb 2017

Researchers show how metabolism drives proliferation of tumor cells

The metabolic state of tumor cells contributes to signals that control the proliferation of tumor cells. Already the German biochemist and Nobel Prize laureate Otto H. Warburg observed in the 1920s that tumor cells radically change their metabolism.

20 Feb 2017

Targeting tumor suppressor protein could be effective treatment for some AML patients, study suggests

Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease.

17 Feb 2017

VIB-KU Leuven scientists identify new mechanism that impacts cancer growth

Scientists at VIB-KU Leuven have identified a new mechanism that impacts tumor growth. The typical lack of oxygen in tumors doesn't only stimulate proliferation, but also offsets the important role of the protein PHD2 as 'cancer cell killer'.

14 Feb 2017

Salk professor receives inaugural Sjöberg Prize for groundbreaking cancer research

Salk Professor Tony Hunter, who holds an American Cancer Society Professorship, has been awarded $500,000 as part of the $1 million Royal Swedish Academy of Sciences' inaugural Sjöberg Prize for Cancer Research for "groundbreaking studies of cellular processes that have led to the development of new and effective cancer drugs."

14 Feb 2017

Glucose deprivation in the brain triggers onset of cognitive decline, research shows

One of the earliest signs of Alzheimer's disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment -- before symptoms of memory problems begin to surface.

31 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

New study explores circadian timekeeping to create genetic knock-out rescue mice

A new study from the laboratory of Hiroki Ueda at the RIKEN Quantitative Biology Center investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice.

22 Dec 2016

Certain anti-diabetic drugs can switch off molecule that plays key role in inflammatory diseases

A molecule thought to play a key role in some inflammatory diseases can be switched off by two widely used medicines, new research has shown.

9 Nov 2016

Phosphorylation News and Research

Scientists find new drug target to improve cardiac output in heart failure patients

Researchers identify mechanism to recover aging of Progeria patients

Researchers show how cellular stress regulates production of hemoglobin

Researchers discover key to reveal secret of reversible aging recovery

Researchers shed light on diverse effects of exercise on individuals

Rogue proteins involved in breast cancer point to potential treatment options

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Simple blood test may soon eliminate need for invasive procedures to detect, monitor cancer

Research findings point to new strategies for tapping into plant energy to produce biofuels, biomaterials

Octapharma uses G:BOX Chemi XX6 imager to accurately characterise large therapeutic proteins

Study reports global quantitative interactomics analysis of protein phosphatome

Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer

Researchers show how metabolism drives proliferation of tumor cells

Targeting tumor suppressor protein could be effective treatment for some AML patients, study suggests

VIB-KU Leuven scientists identify new mechanism that impacts cancer growth

Salk professor receives inaugural Sjöberg Prize for groundbreaking cancer research

Glucose deprivation in the brain triggers onset of cognitive decline, research shows

Could pathogen infection really lead to Alzheimer’s?

New study explores circadian timekeeping to create genetic knock-out rescue mice

Certain anti-diabetic drugs can switch off molecule that plays key role in inflammatory diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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