Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Study examines costs linked with specific inpatient mental health diagnoses for children

Nearly one in 10 hospitalized children have a primary diagnosis of a mental health condition, and depression alone accounts for $1.33 billion in hospital charges annually, according to a new analysis led by UCSF Benioff Children's Hospital.

19 Mar 2014

Dampened reward response tied to schizophrenia risk

The striatal hypoactivation during reward anticipation seen in patients with schizophrenia is also present in their unaffected first-degree relatives, research shows.

17 Mar 2014

EEG-based biomarker can help predict psychotic disorder in high-risk individuals

Only one third of individuals identified as being at clinical high risk for psychosis actually convert to a psychotic disorder within a 3 year follow-up period. This risk assessment is based on the presence of sub-threshold psychotic-like symptoms.

17 Mar 2014

Stress sensitivity adds to psychosis vulnerability

Sensitivity to stress may help to determine whether traumatic life events will lead to psychosis, research suggests.

13 Mar 2014

Innovative study uses pharmacogenomic test to treat patients with psychotic disorders

ValueOptions, Inc. a health improvement company specializing in mental and emotional well-being and recovery, and Genomind, a personalized medicine company, today announced an innovative study that uses pharmacogenomic testing to treat patients diagnosed with psychotic disorders, including schizophrenia and bipolar disorder.

11 Mar 2014

Neurocognition, negative symptom effects in psychotic prodrome clarified

The contribution of neurocognition and negative symptoms to impaired social and role functioning in patients at clinical high risk of psychosis is important enough to warrant targeting both with therapeutic interventions, say researchers.

7 Mar 2014

Inflammation and stress combine in bipolar and schizophrenia subtypes

Researchers have found that some individuals with bipolar disorder or schizophrenia have combined stress response and immune dysfunctions.

6 Mar 2014

Drug abuse does not always lead to psychosis readmission

Cannabis or stimulant abuse disorders do not necessarily predict a negative outcome for patients with first-episode psychosis, Australian researchers report.

5 Mar 2014

ACADIA Pharmaceuticals proposes to sell common stock in underwritten public offering

ACADIA Pharmaceuticals Inc. (NASDAQ: ACAD) today announced that it intends to offer and sell, subject to market and other conditions, $150,000,000 of shares of its common stock in an underwritten public offering.

4 Mar 2014

Further support for hippocampal volume as psychosis biomarker

Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes provide further evidence that reduced hippocampal volume is a consistent feature of schizophrenia.

27 Feb 2014

Advanced paternal age effects extend to several psychiatric disorders

The effect of advanced paternal age at childbearing on the psychiatric morbidity risk of their children extends to several psychiatric disorders and particularly bipolar disorder, findings from a sibling-comparison study show.

27 Feb 2014

Substance abuse worsens course of first-episode psychosis

Patients with first-episode psychosis who also present with substance abuse have a higher rate of hospitalisation after 12 months than their peers who do not, an Italian study reports.

25 Feb 2014

Factors predicting disengagement from psychosis early intervention identified

A study of first-episode psychosis patients in Hong Kong has found that those with fewer negative symptoms at presentation and poor medication compliance were more likely than others to disengage from an early intervention program.

21 Feb 2014

Psychotherapies have specific effects on psychosis symptoms

There are small but robust differences in the effects of different psychotherapies on psychosis symptoms, say the authors of a meta-analysis.

20 Feb 2014

Stereotype awareness impacts self-esteem in schizophrenia

Patients with psychosis with higher self-esteem have less awareness of the stereotypes associated with mental health patients and their families, research shows.

19 Feb 2014

Verbal memory may signal disease course in first-episode psychosis

Verbal memory appears to be a predictor of clinical remission in patients with first-episode psychosis, according to Canadian researchers writing in Schizophrenia Research.

18 Feb 2014

Interhemispheric disconnectivity highlighted in bipolar disorder

Research shows that patients with bipolar I disorder have reduced white matter integrity, including in the corpus callosum, which connects the brain’s hemispheres.

18 Feb 2014

‘Healthy living’ programme fails to lower BMI in overweight psychosis patients

A “healthy living” intervention focused on exercise and diet has failed to impact body mass index in overweight people with psychosis when evaluated in the setting of a randomised controlled trial.

14 Feb 2014

Persons with severe symptoms of mental illness are at higher risk for being HIV-infected

People receiving mental health care are up to four times more likely to be infected with HIV than the general population, according to a new study published Feb. 13 in the American Journal of Public Health from researchers at Penn Medicine and other institutions who tested over 1,000 patients in care in Philadelphia and Baltimore.

14 Feb 2014

Common mutations produce typical schizophrenia brain changes

Mutations in dopamine-related genes have a dose-response effect on prefrontal activation during emotional response inhibition in healthy adults, a study shows.

13 Feb 2014