Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Psychotherapies have specific effects on psychosis symptoms

There are small but robust differences in the effects of different psychotherapies on psychosis symptoms, say the authors of a meta-analysis.

20 Feb 2014

Stereotype awareness impacts self-esteem in schizophrenia

Patients with psychosis with higher self-esteem have less awareness of the stereotypes associated with mental health patients and their families, research shows.

19 Feb 2014

Verbal memory may signal disease course in first-episode psychosis

Verbal memory appears to be a predictor of clinical remission in patients with first-episode psychosis, according to Canadian researchers writing in Schizophrenia Research.

18 Feb 2014

Interhemispheric disconnectivity highlighted in bipolar disorder

Research shows that patients with bipolar I disorder have reduced white matter integrity, including in the corpus callosum, which connects the brain’s hemispheres.

18 Feb 2014

‘Healthy living’ programme fails to lower BMI in overweight psychosis patients

A “healthy living” intervention focused on exercise and diet has failed to impact body mass index in overweight people with psychosis when evaluated in the setting of a randomised controlled trial.

14 Feb 2014

Persons with severe symptoms of mental illness are at higher risk for being HIV-infected

People receiving mental health care are up to four times more likely to be infected with HIV than the general population, according to a new study published Feb. 13 in the American Journal of Public Health from researchers at Penn Medicine and other institutions who tested over 1,000 patients in care in Philadelphia and Baltimore.

14 Feb 2014

Common mutations produce typical schizophrenia brain changes

Mutations in dopamine-related genes have a dose-response effect on prefrontal activation during emotional response inhibition in healthy adults, a study shows.

13 Feb 2014

Urinary tract infections linked to acute psychosis relapse

Patients with an acute episode of psychosis have a high incidence of urinary tract infections, report researchers.

12 Feb 2014

Jazz Pharmaceuticals' Versacloz now commercially available in the U.S. for schizophrenia

Jazz Pharmaceuticals plc today announced U.S. commercial availability of Versacloz (clozapine, USP) oral suspension, the first and only oral suspension clozapine for severely ill treatment-resistant schizophrenia patients or those at risk of recurrent suicidal behavior with schizophrenia or schizoaffective disorder.

11 Feb 2014

Self-disorders highly specific to schizophrenia spectrum

Self-disorders – also known as anomalous self-experiences – are highly specific to individuals with schizophrenia-spectrum disorders, Danish research indicates.

11 Feb 2014

Maternal influenza link to bipolar disorder refined

Research suggests that maternal influenza during pregnancy may increase the risk for bipolar disorder with psychotic features in offspring, rather than being associated with bipolar disorder per se.

6 Feb 2014

Psychiatrists urged to monitor metabolic changes in psychosis patients

Japanese psychiatrists are largely aware of the metabolic abnormalities that may arise from antipsychotic treatment, but most do not monitor their patients sufficiently, research shows.

30 Jan 2014

Impaired cognitive insight linked to delusions in psychosis risk

High levels of self-certainty, one aspect of cognitive insight, are associated with the presence of delusional symptoms in people with at-risk mental states, a study shows.

29 Jan 2014

Hippocampal activity may reflect ‘core’ schizophrenia traits

Hippocampal function may be a useful biomarker for the response of patients with schizophrenia to medication, research suggests.

28 Jan 2014

Psychosis risk factors have limited predictive power

Factors known to be linked to schizophrenia risk have little predictive power at either the individual or population level, report researchers.

24 Jan 2014

Social contact problems warn of future psychosis

Difficulties with social contact in adolescents from the general population are associated with later development of psychosis, say researchers.

23 Jan 2014

Childhood bereavement contributes to future psychosis risk

The death of a close family member during childhood is associated with an increased risk for future psychosis, research shows.

22 Jan 2014

Brain imaging via MRI scans may be useful biomarker for early detection of subtle developmental abnormalities

Researchers at Penn Medicine have generated a brain development index from MRI scans that captures the complex patterns of maturation during normal brain development.

22 Jan 2014

Experiencing family death in childhood linked with increased risk of psychosis

Experiencing a family death in childhood is associated with a small but significant increase in risk of psychosis, suggests a paper published today on bmj.com.

21 Jan 2014

Psychosis risk following childhood abuse not down to genetics

Familial risk for psychosis does not account for the association between abuse during childhood and the later development of schizophrenia, a study suggests.

20 Jan 2014