Wound News and Research

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Two proteins joined together using a free-standing, rigid link

Researchers at the Paul Scherrer Institute PSI are the first to have joined two proteins together by means of a free-standing, rigid link. The structural element holds the two protein molecules together at a defined distance and angle, much the way a barbell handle connects two weights.

29 Sep 2021

Exploring the polymerase of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Mathematical constructions of SARS-CoV-2 action could help fine-tune prevention and treatment

Mathematical constructions of the action of SARS-CoV-2 and its multiple spikes, which enable its success at infecting cells, can give vaccine developers and pharmaceutical companies alike a more precise picture of what the virus is doing inside us and help fine tune prevention and treatment, mathematical modelers say.

23 Sep 2021

Consumption of common antibiotic during pregnancy can reduce low birth weight and premature births

A common antibiotic has been found to reduce low birth weight and premature births, if taken during pregnancy, in countries where malaria is endemic, according to a research review.

22 Sep 2021

Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

First dose of COVID-19 mRNA vaccine (BNT162b2) reduced platelet polyP levels in young females

In a recent study, scientists have tested the hypothesis that indicates the role of polyP in the COVID-19 mRNA vaccine-induced immune responses.

20 Sep 2021

Study points to a possible new approach for treating MRSA superbug

A study released in STEM CELLS Translational Medicine, by researchers at the Baker Institute for Animal Health, part of Cornell University's College of Veterinary Medicine, Ithaca, N.Y., details in a relevant ex vivo model how treating wounds with the secretion of a type of stem cell called mesenchymal stromal cell (MSC) effectively reduced methicillin-resistant Staphylococcus aureus – better known as MRSA viability and stimulated the surrounding skin cells to build up a defense against the bacterial invader.

16 Sep 2021

Researchers focus on improving biomaterials used for bone and tissue repair

Bone injuries in the face and skull - known as craniomaxillofacial defects - can be caused by sports injuries, vehicle accidents, or battlefield injuries.

14 Sep 2021

‘No-touch’ technique to remove leg veins leads to better outcomes after heart bypass surgery

When a modified surgical technique was used to gently remove sections of leg veins used in coronary artery bypass surgery, the grafts were less likely to become blocked and fewer people had a recurrence of heart-related chest pain, according to new research published today in the American Heart Association's flagship journal Circulation.

13 Sep 2021

Natural killer cells mediate a trade-off between wound healing and bacterial defense

Natural killer cells do not just kill cancer cells or cells infected with viruses, they also mediate a trade-off between wound healing and bacterial defense in skin wounds.

8 Sep 2021

Key cross-government effort underway to ensure Afghans arriving in the UK receive support

A significant cross-government effort is underway, dubbed 'Operation Warm Welcome', to ensure Afghans arriving in the UK receive the vital support they need to rebuild their lives, find work, pursue education and integrate into their local communities.

31 Aug 2021

Researchers develop new drug-free treatment to accelerate healing of chronic diabetic wounds

About one-fourth of people with diabetes develop painful foot ulcers, which are slow to heal due to low oxygen in the wound from impaired blood vessels and increased inflammation. These wounds can become chronic, leading to poor quality of life and potential amputation.

31 Aug 2021

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Recently, a new study published on the pre-print server bioRxiv* examined the effect that maternal asymptomatic COVID-19 had on decidual and peripheral immune cells during the later stage of pregnancy.

30 Aug 2021

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Oncotarget published "Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis" which reported that microscopic imaging, immunocytochemistry, wound healing assay, caspase-cleaved cytokeratin 18 CytoDeath ELISA assay, immunofluorescence labeling assays for apoptosis, hypoxia, Western Blotting, Tunnel assay, measurement of 5-HT secretion by carbon fiber amperometry assay, quantitative methylation-specific PCR, morphologic changes, cell viability, apoptosis activity and the expression levels of phospho-Akt1, Akt1, HIF-1α, PI3K, p21, CAIX, 5-HT, phospho-mTOR, and mTOR in xenografts derived from typical H727 and atypical H720 BC cell lines.

28 Aug 2021

Telepsychiatry in rural health centers expands access to high-quality care for underserved patients

John Nolan served in the U.S. Army and Marines and later worked in law enforcement and as a correctional officer. A career spent dealing with traumatic events led to post-traumatic stress disorder and insomnia. He felt like his life was spinning out of control.

25 Aug 2021

Researchers develop novel sealant patch for preventing intestinal leakage

A burst appendix or a life-threatening intestinal volvulus are emergencies that need to be treated by surgeons immediately. However, a life-saving operation, in which tissue from the digestive tract has to be reattached, bears some risks. After all, everything that is transported through the gastrointestinal tract to the outside world in fact belongs there - and should under no circumstances end up inside the abdominal cavity.

20 Aug 2021

Fetal membranes can heal after injury, study shows

Scientists from Queen Mary University of London and UCL have shown that fetal membranes are able to heal after injury in a new study.

18 Aug 2021

Analysis of landmark vitamin C study challenges the WHO's recommended daily amounts

It was wartime and food was scarce. Leaders of England's effort to wage war and help the public survive during World War II needed to know: Were the rations in lifeboats adequate for survival at sea? And, among several experiments important for public as well as military heath, how much vitamin C did a person need to avoid the deadly disease scurvy?

16 Aug 2021

Surgeons cash in on stakes in private medical device companies

Several orthopedic surgeons who invested in Renovis Surgical Technologies made big money when a Japanese technology giant snatched up the small California medical device company.

10 Aug 2021

New biocompatible glue could quickly seal injured tissues and stop bleeding

Inspired by the sticky substance that barnacles use to cling to rocks, MIT engineers have designed a strong, biocompatible glue that can seal injured tissues and stop bleeding.

9 Aug 2021