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Scientists elucidate 3D structure of protein involved in cancer

The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses.

6 Jun 2018

FDA approves first Neulasta biosimilar to help decrease infection risk during cancer treatment

The U.S. Food and Drug Administration today approved Fulphila (pegfilgrastim-jmdb) as the first biosimilar to Neulasta (pegfilgrastim) to decrease the chance of infection as suggested by febrile neutropenia (fever, often with other signs of infection, associated with an abnormally low number of infection-fighting white blood cells), in patients with non-myeloid (non-bone marrow) cancer who are receiving myelosuppressive chemotherapy that has a clinically significant incidence of febrile neutropenia.

4 Jun 2018

Discovering Antibodies with Universal Specificity

Professor Hedda Wardemann discusses our current knowledge of antibody specificity and how her research team are challenging this, through the discovery of anti-bacterial antibodies with universal specificity.

1 Jun 2018

Scientists develop new method to speed up genome evolution of baker's yeast

Scientists have created a new way of speeding up the genome evolution of baker's yeast Saccharomyces cerevisiae, the same yeast people use for bread and beer production, to develop a synthetic yeast strain that can be transformed on demand for use in various industrial applications.

26 May 2018

Study links cell size with commitment to division

How does a cell know when to divide? We know that hundreds of genes contribute to a wave of activity linked to cell division, but to generate that wave new research shows that cells must first grow large enough to produce four key proteins in adequate amounts.

24 May 2018

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Geneticists have been using model organisms ranging from the house mouse to the single-cell bakers' yeast, Saccharomyces cerevisiae, to study basic biological processes that regulate human development and physiology, and that can be compromised in various diseases.

22 May 2018

First epoetin alfa biosimilar receives FDA approval to treat certain types of anemia

The U.S. Food and Drug Administration today approved Retacrit (epoetin alfa-epbx) as a biosimilar to Epogen/Procrit (epoetin alfa) for the treatment of anemia caused by chronic kidney disease, chemotherapy, or use of zidovudine in patients with HIV infection.

16 May 2018

Increasingly failing communication between cells' organelles is main cause of aging, shows study

A basic discovery of how the cellular functions are connected to control aging is presented in the journal Cell Metabolism.

11 May 2018

Researchers harness the precision of CRISPR to knock out single genes in yeast

Researchers have used CRISPR-Cas9 to develop a technology that can precisely target any gene in the yeast species Saccharomyces cerevisiae.

8 May 2018

New survey highlights need for BV awareness and education to ensure proper care

Lupin Pharmaceuticals Inc., the U.S. wholly owned subsidiary of Lupin Limited, dedicated to delivering high-quality medications trusted by healthcare professionals and women across many treatment areas, has partnered with the National Association of Nurse Practitioners in Women's Health to conduct a national online survey of 301 HCPs (including OB/GYNs and NP/PAs) who treat women with bacterial vaginosis (BV).

4 May 2018

Researchers discover glutamine-dependent activation of cell growth and autophagy

The human body consists of about 35 trillion cells, so it could be said that overall body growth is the growth of individual cells.

3 May 2018

New GP-write project to develop ultra-safe cells resistant to natural viruses

The Center for Excellence in Engineering Biology and the leadership of Genome Project-write today announced its first grand-scale community-wide project, to develop "ultra-safe cells" that resist natural viruses and potentially radiation, freezing, aging and cancer.

2 May 2018

Study examines how higher-order gene combinations help maintain normal cell physiology

We inherit many traits from our parents including the color of our eyes and hair. Unfortunately, we also inherit risk factors for certain diseases such as cancer, heart disease, and diabetes. Understanding those genetic connections can help prevention efforts and develop new life-saving treatments to combat these diseases.

20 Apr 2018

CNIO researchers determine structure of protein complex related to cell survival

A team from the Spanish National Cancer Research Centre has determined for the first time the high-resolution structure of a complex (R2TP) involved in key processes for cell survival and in diseases such as cancer.

16 Apr 2018

Aberrant protein prevents self-cleaning of nerve cells in ALS

Scientists have discovered that TDP-43 interferes with lysosomal pathways responsible for its clearance and induces autophagy in ALS.

12 Apr 2018

UCLA researchers tweak CRISPR to accelerate genomic editing

The powerful gene-editing tool, CRISPR, has revolutionized research by allowing scientists to snip and patch DNA with remarkable precision. But tracking the impact of these changes on gene function can be time-consuming. Researchers currently analyze each edit one at a time, a process that can take weeks.

9 Apr 2018

Sulfur amino acid restriction consistently demonstrates range of health benefits in animals

The longevity and health improvements seen in animals on sulfur amino acid-restricted diets could translate to people, according to Penn State College of Medicine researchers who recently conducted a review of published studies. More research is needed to confirm the benefits in people, the scientists said.

4 Apr 2018

Older Americans are hooked on vitamins despite scarce evidence they work

When she was a young physician, Dr. Martha Gulati noticed that many of her mentors were prescribing vitamin E and folic acid to patients. Preliminary studies in the early 1990s had linked both supplements to a lower risk of heart disease.

4 Apr 2018

Leading experts to promote cardiovascular health at EuroPrevent 2018

The impact of nutrition and lifestyle on cardiovascular health will be key elements discussed by health professionals during EuroPrevent 2018 in Ljubljana, Slovenia, in April. EuroPrevent is the annual congress of the European Association of Preventive Cardiology, a branch of the European Society of Cardiology.

23 Mar 2018

Researchers uncover cause of rare childhood neurodegenerative disease

Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells.

23 Mar 2018

Yeast News and Research

Scientists elucidate 3D structure of protein involved in cancer

FDA approves first Neulasta biosimilar to help decrease infection risk during cancer treatment

Discovering Antibodies with Universal Specificity

Scientists develop new method to speed up genome evolution of baker's yeast

Study links cell size with commitment to division

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

First epoetin alfa biosimilar receives FDA approval to treat certain types of anemia

Increasingly failing communication between cells' organelles is main cause of aging, shows study

Researchers harness the precision of CRISPR to knock out single genes in yeast

New survey highlights need for BV awareness and education to ensure proper care

Researchers discover glutamine-dependent activation of cell growth and autophagy

New GP-write project to develop ultra-safe cells resistant to natural viruses

Study examines how higher-order gene combinations help maintain normal cell physiology

CNIO researchers determine structure of protein complex related to cell survival

Aberrant protein prevents self-cleaning of nerve cells in ALS

UCLA researchers tweak CRISPR to accelerate genomic editing

Sulfur amino acid restriction consistently demonstrates range of health benefits in animals

Older Americans are hooked on vitamins despite scarce evidence they work

Leading experts to promote cardiovascular health at EuroPrevent 2018

Researchers uncover cause of rare childhood neurodegenerative disease

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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