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Simplest, reinforced FDA warnings found effective

The impact of efforts by the U.S. Food and Drug Administration to notify the general public and health care providers about unanticipated risks from approved medications has been "varied and unpredictable," according to a systematic review of published studies about FDA warnings and alerts over the last 20 years.

20 Jan 2012

Combination of gefitinib and miRNA-inhibitor might effectively treat NSCLC

New research published in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.

20 Jan 2012

Cedars-Sinai's annual Brainworks program to take place on Feb. 13

Taking turns gazing into a surgical microscope, 130 seventh- and eighth-graders from Los Angeles area schools will see a phantom skull and perform virtual surgery - and many could catch a glimpse of the future.

20 Jan 2012

Novel nano-carrier platform shows promise for cancer drug delivery

A new class of nanoparticles, synthesized by a UC Davis research team to prevent premature drug release, holds promise for greater accuracy and effectiveness in delivering cancer drugs to tumors. The work is published online in Angewandte Chemie, a leading international chemistry journal.

20 Jan 2012

WSU professors receive NSF grant to develop math model of liver metabolism

Predicting problems in one of the body's most complex organs soon may become easier because of work being done by Wayne State University researchers.

20 Jan 2012

More than half of high-risk Americans do not receive HBV vaccination

Although there is an effective vaccine for hepatitis B and public health officials have a strong sense of who is at highest risk for the infectious liver disease, tens of thousands of people in the United States contract the virus every year. According to a new study by researchers at Brown University, missed opportunities to administer the vaccine continue to be a reason why infections persist.

20 Jan 2012

MSU focuses on cultural competency to help turn tide of new infections

While global attention to HIV/AIDS remains strong, a lack of focus on prevention strategies is stonewalling health experts in many developing nations, specifically in the Caribbean.

20 Jan 2012

Blog interviews UCLA professor about highly drug-resistant TB

The Los Angeles Times' "Booster Shots" blog features an interview with Otto Yang, a professor at the Geffen School of Medicine at UCLA, who speaks about drug-resistant tuberculosis (TB) and the implications of a highly drug-resistant strain found in India.

20 Jan 2012

Upper GI bleeding causes serious health problems in patients with kidney failure

Bleeding in the upper gastrointestinal (GI) tract causes serious health problems—and even early deaths—for many patients with kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

20 Jan 2012

Inflammation enhances pancreatic cancer cell progression

Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology at the Perelman School of Medicine, University of Pennsylvania, and Andrew Rhim, MD, a Gastroenterology Fellow in the Stanger lab, discovered that pancreatic cancer cells in an animal model begin to spread before clinically obvious tumor tissue is detected.

20 Jan 2012

First lady praises academic institutions for dedication to America's warriors

As part of a White House effort to ensure that America's military heroes receive care worthy of their service, the UCLA Health System and the David Geffen School of Medicine at UCLA have pledged to mobilize their uniquely integrated missions in education, research and clinical care to help train physicians to meet the special needs of veterans, active service members and their families.

20 Jan 2012

About half of eligible and due services are missed during PHEs

More than 20 percent of U.S. adults receive periodic health examinations (PHE) each year, yet new research shows that patients who have an annual routine visit to their doctor may not receive recommended preventive screening tests and counseling services that could benefit their health.

20 Jan 2012

MSC-mediated RNAi transfer holds promise for Huntington's disease

A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington's disease, a hereditary brain disorder that causes progressive uncontrolled movements, dementia and death.

20 Jan 2012

Viewpoints: Health care and the federal deficit; Doctors reassessing health law

We don't have a generalized overspending problem. We have a humongous health-care problem. … Try to ignore the current shallowness in American politics, if you can, and assume that the federal budget deficit will be among the major issues of the 2012 campaign. It certainly should be, for while everyone wants a lower deficit, the two parties have starkly different visions of how to get there.

20 Jan 2012

Accelerated growth may increase risk of asthma symptoms in young children

Accelerated growth in the first three months of life, but not fetal growth, is associated with an increased risk of asthma symptoms in young children, according to a new study from The Generation R Study Group at Erasmus Medical Center in the Netherlands.

20 Jan 2012

Distal-less gene plays a critical role in development of fruit fly olfactory system

Fruit flies don't have noses, but a huge part of their brains is dedicated to processing smells. Flies probably rely on the sense of smell more than any other sense for essential activities such as finding mates and avoiding danger. UW-Madison researchers have discovered that a gene called distal-less is critical to the fly's ability to receive, process and respond to smells.

20 Jan 2012

Springer celebrates its 50,000th eBook

Springer celebrates its 50,000th eBook, available on its online platform SpringerLink. This milestone underscores Springer's position as the largest eBook publisher and emphasizes SpringerLink's dominance in offering the world's most comprehensive online collection of science, technology and medicine (STM) journals, books and reference works.

20 Jan 2012

New federal drug label recommendations for CKD patients

The U.S. Food and Drug Administration (FDA) recently recommended that clinicians be more conservative when they prescribe chronic kidney disease (CKD) patients with drugs that treat red blood cell deficiencies. But the drug label's recommendations fall short, according to two commentaries appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology.

20 Jan 2012

Study explains gender-related incidence of liver cancer

Men are four times more likely to develop liver cancer compared to women, a difference attributed to the sex hormones androgen and estrogen. Although this gender difference has been known for a long time, the molecular mechanisms by which estrogens prevent -- and androgens promote -- liver cancer remain unclear.

20 Jan 2012

Birth weight plays a role in autism spectrum disorder

Although the genetic basis of autism is now well established, a growing body of research also suggests that environmental factors may play a role in this serious developmental disorder affecting nearly one in 100 children. Using a unique study design, a new study suggests that low birth weight is an important environmental factor contributing to the risk of autism spectrum disorder.

20 Jan 2012