Genetic News and Research

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Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

In all living organisms, DNA replication is essential to ensure the genetic fidelity of the next generation. However, bacteria can also transfer genetic information horizontally to other bacteria.

3 Feb 2023

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

To commemorate World Cancer Day, we spoke to a multidisciplinary team of researchers from The Institute of Cancer Therapeutics (ICT) based at the University of Bradford about their work in cancer research.

3 Feb 2023

Pulmonary morphopathology in COVID-19 caused by the B.1.617.2 Delta variant

Researchers examined the histopathological condition of the lungs of patients who died from COVID-19 caused by the SARS-CoV-2 Delta (B.1.617.2) variant.

3 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

Researchers develop a cell line to address the challenges facing cellular modeling of disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

Researchers document link between higher risk of maternal mortality and sickle cell disease

Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared to those without it.

3 Feb 2023

New nanotechnology-based test can detect and profile prostate cancers even in microscopic amounts

Cedars-Sinai Cancer investigators have developed a new nanotechnology-based test that can detect and profile prostate cancers - even in microscopic amounts.

2 Feb 2023

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

An unexpected discovery made by experts at the Brain Tumor Center at Cincinnati Children's while studying a rare-but-deadly type of brain tumor may also lead to improved treatments for several other forms of cancer that share a common influencing factor called a YAP fusion protein.

2 Feb 2023

Understanding the mechanism of bedaquiline resistance in Mycobacterium marinum

Announcing a new article publication for Zoonoses journal. As infections caused by nontuberculous mycobacteria (NTM) are rapidly increasing globally, a need exists for developing novel antibiotics and discovering the mechanism of resistance

2 Feb 2023

UVA researchers discover genes responsible for the development of coronary artery disease

University of Virginia researchers and their collaborators have identified genes that play key roles in the development of coronary artery disease, the No. 1 cause of death worldwide.

2 Feb 2023

Novel tool uses AI to predict the efficacy of genome-editing repair options

Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options.

2 Feb 2023

Five major adverse pregnancy outcomes associated with long term risks of ischemic heart disease

Women who experience any of five major pregnancy complications, such as preterm birth and pre-eclampsia, show an increased risk of ischemic heart disease up to 46 years after delivery, finds a study from Sweden published by The BMJ today.

2 Feb 2023

People with poor oral health may be more likely to show signs of declining brain health

Taking care of your teeth and gums may offer benefits beyond oral health such as improving brain health, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.

2 Feb 2023

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Researchers evaluated the clinical and genetic characteristics of acute myeloid leukemia (AML) patients with a mutant Ikaros zinc finger protein 1 (IKZF1).

2 Feb 2023

Integrated model helps enhance patient care for pediatric brain tumors

The Brain Tumor Center at Children's Hospital Los Angeles is one of the largest and most comprehensive pediatric brain tumor programs in the country, integrating experts from multiple specialty areas into a coordinated treatment team.

2 Feb 2023

Knowing your cholesterol level can be a crucial factor in overall health

On a top 10 list of things to do, getting your cholesterol level checked likely doesn't make the cut – but no matter your age, knowing your numbers can be a crucial factor in overall health.

2 Feb 2023

Deep-learning based filter removes false positives, improves the accuracy of cancer diagnosis

Next-generation cancer strategies rely on next-generation gene sequencing (NGS), which paves the way for new techniques and tools to detect mutations and determine patient therapy.

1 Feb 2023

New optogenetic tool to study and modulate plasticity in the cerebellum

Light can trigger a signaling cascade in the cerebellum. This also illuminates processes that play an important role in cerebellar diseases.

1 Feb 2023

Highly effective detection of cancer biomarkers using CRISPR

Most cancer diagnostic techniques rely on uncomfortable and invasive procedures, such as biopsies, endoscopies or mammograms.

1 Feb 2023

Genetic News and Research

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

Pulmonary morphopathology in COVID-19 caused by the B.1.617.2 Delta variant

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers develop a cell line to address the challenges facing cellular modeling of disease

Researchers document link between higher risk of maternal mortality and sickle cell disease

New nanotechnology-based test can detect and profile prostate cancers even in microscopic amounts

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

Understanding the mechanism of bedaquiline resistance in Mycobacterium marinum

UVA researchers discover genes responsible for the development of coronary artery disease

Novel tool uses AI to predict the efficacy of genome-editing repair options

Five major adverse pregnancy outcomes associated with long term risks of ischemic heart disease

People with poor oral health may be more likely to show signs of declining brain health

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Integrated model helps enhance patient care for pediatric brain tumors

Knowing your cholesterol level can be a crucial factor in overall health

Deep-learning based filter removes false positives, improves the accuracy of cancer diagnosis

New optogenetic tool to study and modulate plasticity in the cerebellum

Highly effective detection of cancer biomarkers using CRISPR

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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