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Foundation Medicine completes $25M Series A financing led by Third Rock Ventures

Foundation Medicine, a personalized cancer medicine company that aims to bring comprehensive cancer genome analysis into routine clinical care, today announced it has completed a $25 million Series A financing led by Third Rock Ventures.

15 Apr 2010

Decoding genomes from 25,000 cancer samples

The International Cancer Genome Consortium (ICGC) today set out its bold plan to decode the genomes from 25,000 cancer samples and create a resource of freely available data that will help cancer researchers around the world. The publication outlines research design and projects as well as the important ethical framework for this science.

15 Apr 2010

Study: Atorvastatin may slow down MS progression

A UCSF-led study examining the impact of statins on the progression of multiple sclerosis found a lower incidence of new brain lesions in patients taking the cholesterol-lowering drug in the early stages of the disease as compared to a placebo.

15 Apr 2010

New findings may allow clinicians to prevent complications in pregnancy

Researchers at Mount Sinai School of Medicine have found that epigenetic marks on human placentas change from the first trimester of pregnancy to the third, a discovery that may allow clinicians to prevent complications in pregnancy.

15 Apr 2010

MDA awards over $21M in grants for advancing critical neuromuscular research

Forty-two medical researchers and their labs have been awarded more than $21 million in grants by the Muscular Dystrophy Association to advance critical neuromuscular research in 2010. Many of the grants are multi-year awards to be dispersed over the next three years.

15 Apr 2010

University of Pennsylvania School of Medicine ranked #2 among nation's research-oriented medical schools

The University of Pennsylvania School of Medicine has been ranked #2 among the nation's research-oriented medical schools, according to the annual survey by U.S. News & World Report, rising from #3 in last year's survey. The prestigious survey of the nation's 126 fully-accredited medical schools ranked Harvard University in first place and John Hopkins University third.

15 Apr 2010

Universal screening test for CMV infection is not effective, says study

DNA analysis of dried blood samples routinely collected from newborns did not effectively identify an infection that is a major cause of hearing loss in children, according to a study in the April 14 issue of JAMA.

15 Apr 2010

Opinions: Health and living conditions; H1N1, one year later; global water shortages

Former U.S. Senate Majority Leader Bill Frist (R-Tenn.) and Habitat for Humanity CEO Jonathan Reckford write in an Atlanta Journal-Constitution opinion piece about the need to "address the constant crisis families face daily in deplorable living conditions."

15 Apr 2010

Genzyme presents 4-year follow-up data from Phase 2 MS trial at neurology meeting

Genzyme Corporation today reported four-year follow-up data from its completed Phase 2 multiple sclerosis (MS) trial showing an estimated 71 percent of alemtuzumab treated patients remain free of clinically-active disease as much as three years after most patients received their last course of the investigational compound. The data were presented at the American Academy of Neurology annual meeting.

15 Apr 2010

New data from Pfizer Oncology's pipeline to be presented at AACR 2010

Pfizer Oncology announced today that it will present new data from the company's pipeline, including two novel, dual PI3K/mTOR inhibitors (PF-04691502 and PKI-587, also known as PF-05212384); crizotinib (PF-02341066), an ALK inhibitor that also inhibits c-MET; and PF-04605412, an anti-α5β1 inhibitor.

15 Apr 2010

Pancreatic Cancer Action Network, AACR awarded four Innovative Grants for pancreatic cancer research

The Pancreatic Cancer Action Network and the American Association for Cancer Research awarded four Innovative Grants; three Career Development Awards; one Pathway to Leadership Grant; and one Fellowship Award to outstanding researchers for their innovative research proposals which have the potential to lead to medical breakthroughs in the treatment of pancreatic cancer.

15 Apr 2010

Genomic component playing key role in promoting breast cancer progression discovered

Life Technologies Corporation today announced that its scientists have teamed with researchers from Stanford University School of Medicine, and other institutions to discover a genomic component that plays a key role in promoting breast cancer progression. A study published today in the journal Nature details how levels of a specific kind of non-coding RNA molecule in primary breast tumors regulate metastasis and tumor invasiveness and may be an important target for cancer diagnosis and therapy.

15 Apr 2010

Bedtime video-games have no significant effect on adolescents’ sleep patterns

A study in the April 15 issue of the Journal of Clinical Sleep Medicine suggests that playing a video game before bedtime has only a mild effect on the sleep of older male teens.

15 Apr 2010

Artificial pancreas system succeeds in maintaining near-normal glucose levels

An artificial pancreas system that closely mimics the body's blood sugar control mechanism was able to maintain near-normal glucose levels without causing hypoglycemia in a small group of patients. The system, combining a blood glucose monitor and insulin pump technology with software that directs administration of insulin and the blood-sugar-raising hormone glucagon, was developed at Boston University.

15 Apr 2010

New technique improves cosmetic breast reconstruction in athletic cancer patients

A new technique using tissue from those below-the-waist "love handles" improves cosmetic breast reconstruction in slim, athletic cancer patients without adequate fat sources elsewhere, a small Johns Hopkins study has found. The method also turns out to be less complicated than other options for surgeons as well, the research shows.

15 Apr 2010

HHS quality report 2009 shows increase in hospital-acquired infections

"The Health and Human Services department's 2009 quality report to Congress found 'very little progress' on eliminating hospital-acquired infections and called for 'urgent attention' to address the shortcomings — first brought to light a decade ago." Specifically, the report found that, for three out of the five major types of serious hospital-related infections, the rate of illness increased.

15 Apr 2010

CHPPR survey: 58% of Americans support repealing health care reform legislation

Fifty-eight percent of Americans (96 percent of Republicans, 10 percent of Democrats and 54 percent of Independents) support repealing the health care reform legislation that was signed into law by President Barack Obama in March, according to a new national survey conducted April 6 - 10 by researchers from Indiana University's Center for Health Policy and Professionalism Research.

15 Apr 2010

Potential new drug for treatment of MS to be presented at AAN Annual Meeting

Researchers from Mount Sinai School of Medicine will present several studies at the American Academy of Neurology Annual Meeting, including a potential new drug for the treatment of multiple sclerosis and surprising trends showing a reduction in the disease's severity. The meeting will take place April 10-17 in Toronto.

15 Apr 2010

Researchers identify new strategy for treating acute myeloid leukemia

Researchers have identified a self-feeding "vicious circle" of molecules that keeps acute leukemia cells alive and growing and that drives the disease forward.

15 Apr 2010

Tengion completes initial 6M common stock public offering

Tengion, Inc., a regenerative medicine company focused on discovering, developing, manufacturing and commercializing neo-organs and neo-tissues, today announced the completion of its initial public offering of 6,000,000 shares of common stock at a price of $5.00 per share. The net proceeds of the offering to Tengion, after deducting underwriting discounts and commissions and estimated offering expenses payable by Tengion, were approximately $26.0 million.

15 Apr 2010