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GUVAX reports successful results in phase I study of oral, Escherichia coli diarrhea vaccine

The University of Gothenburg Vaccine Research Institute (GUVAX) announces successful results in a placebo controlled phase I study of an oral, inactivated Escherichia coli diarrhea vaccine.

22 May 2013

Rice University computational study tracks regulatory mechanisms of E. coli cells

Environment is not the only factor in shaping regulatory patterns -- and it might not even be the primary factor, according to a new Rice University study that looks at how cells' protein networks relate to a bacteria's genome.

22 May 2013

U-M-led researchers examine factors that contribute to resurgence of pertussis

Whooping cough has exploded in the United States and some other developed countries in recent decades, and many experts suspect ineffective childhood vaccines for the alarming resurgence.

21 May 2013

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

20 May 2013

Sorrento Therapeutics' anti-MRSA program gets NIAID support

Sorrento Therapeutics, Inc. announced today that its Fast-Track Advanced Technology Small Business Technology Transfer Research grant (#1R42AI098182-02) from the National Institute of Allergy and Infectious Diseases, a division of the National Institutes of Health, supporting the development of novel human antibody therapeutics to combat Staphylococcus aureus (S. aureus or Staph) infections, including methicillin-resistant S. aureus, was renewed for the second year of a two year Phase I grant award.

18 May 2013

Thioridazine works by weakening staphylococcal cell wall, new study reveals

In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as staphylococci (Staphylococcus aureus).

18 May 2013

Bacteria form biofilm to protect against immune system

Bacteria are life forms, which, like all other life forms, struggle for the best living conditions for themselves. Therefore they will try to avoid getting attacked by the human immune system, and therefore they have developed various ways to protect themselves from the human immune system.

15 May 2013

ALKBH7 protein plays key role in controlling programmed necrosis pathway

When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ravaged their DNA.

15 May 2013

Researchers show how cells are driven mainly by water power

Water gives life. Researchers at Linköping University in Sweden now show how the cells in our bodies are driven mainly by water power - a discovery that in the long run opens the way for a new strategy in cancer therapy.

14 May 2013

Discovery provides vital clues for new antibiotics against MRSA

Scientists at Imperial College London have identified four new proteins that act as receptors for an essential signalling molecule in bacteria such as MRSA.

14 May 2013

Scientists make novel discoveries concerning current vaccine against whooping cough

Scientists at Trinity College Dublin have made novel discoveries concerning the current vaccine against whooping cough that may lead to the development of an improved future vaccine.

13 May 2013

Study identifies national variations in using antibiotics to treat ARS

Antibiotics for acute rhinosinusitis are prescribed frequently- especially for younger adult patients and in primary care settings-despite recent consensus guidelines that discourage antibiotic use in mild cases, according to a study in the May 2013 issue of Otolaryngology-Head and Neck Surgery.

10 May 2013

Research could help battle stubborn bacterial infections that do not respond to antibiotics

Bacteria on a surface wander around and often organize into highly resilient communities known as biofilms. It turns out that they organize in a rich-get-richer pattern similar to many economies, according to a new study by researchers at UCLA, Northwestern University and the University of Washington.

10 May 2013

Physician's choice of words play important role in determining critical end-of-life decisions

A physician's choice of words when talking with family members about whether or not to try cardiopulmonary resuscitation if a critically ill patient's heart stops may influence the decision, according to a study by University of Pittsburgh researchers in the June edition of Critical Care Medicine and now available online.

10 May 2013

Scientists use phages to prevent bacteria on medical devices

They're ba-ack! But in a new disease-fighting role. Viruses that infect and kill bacteria - used to treat infections in the pre-antibiotic era a century ago and in the former Soviet Union today - may have a new role in preventing formation of the sticky "biofilms" of bacteria responsible for infections on implanted medical devices.

9 May 2013

New biosensor detects antibiotic resistance in bacteria, can help fight superbugs

On May 8th JoVE will publish research that demonstrates how a biosensor can detect antibiotic resistance in bacteria. This new technology is a preliminary step in identifying and fighting superbugs, a major public health concern that has led to more deaths than AIDS in the United States in recent years.

9 May 2013

Composition of gut microbiota in new-born baby's gut linked to rate of early infant growth

The composition of gut microbiota in a new-born baby's gut has been linked to the rate of early infant growth, reports research published this week in PLOS Computational Biology.

9 May 2013

Thijn Brummelkamp wins 2013 EMBO Gold Medal for genetic analysis of human disease

EMBO today announced Thijn Brummelkamp of the Netherlands Cancer Institute in Amsterdam as the winner of the 2013 EMBO Gold Medal. The award acknowledges his outstanding work to accelerate the genetic analysis of human disease.

9 May 2013

Gene offers new insights into treatment strategies for deep-vein thrombosis

A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis -- the formation of a harmful clot in a deep vein.

9 May 2013

Genetic loci associated with H pylori bacteria are linked to stomach cancer

Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and stomach ulcers and is linked to stomach cancer, findings that may help explain some of the observed variation in individual risk for H pylori infection, according to a study in the May 8 issue of JAMA.

8 May 2013

Bacterial News and Research

GUVAX reports successful results in phase I study of oral, Escherichia coli diarrhea vaccine

Rice University computational study tracks regulatory mechanisms of E. coli cells

U-M-led researchers examine factors that contribute to resurgence of pertussis

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

Sorrento Therapeutics' anti-MRSA program gets NIAID support

Thioridazine works by weakening staphylococcal cell wall, new study reveals

Bacteria form biofilm to protect against immune system

ALKBH7 protein plays key role in controlling programmed necrosis pathway

Researchers show how cells are driven mainly by water power

Discovery provides vital clues for new antibiotics against MRSA

Scientists make novel discoveries concerning current vaccine against whooping cough

Study identifies national variations in using antibiotics to treat ARS

Research could help battle stubborn bacterial infections that do not respond to antibiotics

Physician's choice of words play important role in determining critical end-of-life decisions

Scientists use phages to prevent bacteria on medical devices

New biosensor detects antibiotic resistance in bacteria, can help fight superbugs

Composition of gut microbiota in new-born baby's gut linked to rate of early infant growth

Thijn Brummelkamp wins 2013 EMBO Gold Medal for genetic analysis of human disease

Gene offers new insights into treatment strategies for deep-vein thrombosis

Genetic loci associated with H pylori bacteria are linked to stomach cancer

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