Enzyme News and Research

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Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.

6 Dec 2016

Researchers develop new compound that can take down defenses in M. tuberculosis

Part of the reason tuberculosis-causing bacteria are so good at colonizing the human body is that they have defenses against the body's immune system.

6 Dec 2016

Research validates effectiveness of world-first dental vaccine

A world-first vaccine developed by Melbourne scientists, which could eliminate or at least reduce the need for surgery and antibiotics for severe gum disease, has been validated by research published this weekend in a leading international journal.

5 Dec 2016

MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

Pericytes are the primary locus of matrix-mellaproteinase-9-dependent (MMP-9) capillary damage and blood leakage during ischemia, according to preclinical findings reported by Medical University of South Carolina investigators in an article published online on November 14, 2016 by The Journal of Neuroscience.

5 Dec 2016

UC Riverside scientists identify mechanism that creates immunity to influenza A virus

A team of researchers, co-led by a University of California, Riverside professor, has found a long-sought-after mechanism in human cells that creates immunity to influenza A virus, which causes annual seasonal epidemics and occasional pandemics.

5 Dec 2016

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue.

5 Dec 2016

Sperm tail enzymes inspire nanobiotechnology

Just like workers in a factory, enzymes can create a final product more efficiently if they are stuck together in one place and pass the raw material from enzyme to enzyme, assembly line-style.

2 Dec 2016

Cornell researchers develop chemical probe activated by UV light to control inflammation

Black light does more than make posters glow. Cornell researchers have developed a chemical tool to control inflammation that is activated by ultraviolet (UV) light.

2 Dec 2016

Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

New research demonstrates that a novel imaging agent can quickly and accurately detect metastasis of prostate cancer, even in areas where detection has previously been difficult.

2 Dec 2016

Scientists devise new radiation-free probe for imaging molecules in the brain

Scientists hoping to get a glimpse of molecules that control brain activity have devised a new probe that allows them to image these molecules without using any chemical or radioactive labels.

2 Dec 2016

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs.

1 Dec 2016

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN.

1 Dec 2016

NASPGHAN clinical practice guidelines recommend screening test for NAFLD in obese children

A screening test for non-alcoholic fatty liver disease (NAFLD)--a serious condition that may have lifelong health consequences--is recommended for all obese children aged nine to eleven years, according to clinical practice guidelines developed by the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and published in the Journal of Pediatric Gastroenterology and Nutrition.

1 Dec 2016

Okayama University researchers find way to prevent replication of influenza viral RNA

Researchers at Okayama University have successfully cleaved influenza viral RNA to prevent its replication using novel artificial RNA restriction enzymes in laboratory cell cultures.

30 Nov 2016

Mildly elevated body iron contributes to prevalence and incidence of type 2 diabetes

Even mildly elevated body iron contributes to the prevalence and incidence of type 2 diabetes, according to research from the University of Eastern Finland.

30 Nov 2016

Researchers find way to make changes to enzyme-driven assembly line to improve antibiotics

Researchers from North Carolina State University have discovered a way to make pinpoint changes to an enzyme-driven "assembly line" that will enable scientists to improve or change the properties of existing antibiotics as well as create designer compounds.

30 Nov 2016

New research shows chitosan bioplastics may help seal tissue tears or other injuries

Chitosan, a biomaterial derived from the chitin shells of crustaceans and insects, has already been developed by scientists at Harvard's Wyss Institute for Biologically Inspired Engineering into an environmentally-friendly and fully biodegradable substitute for plastic.

29 Nov 2016

Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists from the Lomonosov Moscow State University in cooperation with colleagues have worked out a safe, not that expensive and highly efficient method, which allows to speed up and improve searching of new germicides.

29 Nov 2016

Enzyme research provides new insights into pathophysiology of depression

Despite the fact that more than four percent of the world's population suffer from depression, and even though approximately 1,500 individuals commit suicide each year in Sweden, the understanding of the pathophysiology of depression remains unclear and only a few new discoveries of mechanisms behind it have been made in recent years.

29 Nov 2016

Enzyme News and Research

Enzyme that cleaves beta carotene may control testosterone levels

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

Researchers develop new compound that can take down defenses in M. tuberculosis

Research validates effectiveness of world-first dental vaccine

MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

UC Riverside scientists identify mechanism that creates immunity to influenza A virus

Research unlocks potential new therapies for inflammatory diseases

Sperm tail enzymes inspire nanobiotechnology

Cornell researchers develop chemical probe activated by UV light to control inflammation

Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

Scientists devise new radiation-free probe for imaging molecules in the brain

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

NASPGHAN clinical practice guidelines recommend screening test for NAFLD in obese children

Okayama University researchers find way to prevent replication of influenza viral RNA

Mildly elevated body iron contributes to prevalence and incidence of type 2 diabetes

Researchers find way to make changes to enzyme-driven assembly line to improve antibiotics

New research shows chitosan bioplastics may help seal tissue tears or other injuries

Scientists develop safe, highly efficient method to improve searching of new germicides

Enzyme research provides new insights into pathophysiology of depression

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Advancing degrader and proximity-based drug development

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