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HCV patients with hepatocellular carcinoma history could re-develop illness during or after taking DAAs

Data from a new study show that patients with Hepatitis C virus (HCV) taking direct-acting antiviral treatments (DAAs), who have previously fought off hepatocellular carcinoma (HCC), the most common form of liver cancer,1 had a 'high rate' of re-developing their illness.

13 Apr 2016

Studies offer alternative conclusions on efficacy of DAAs for HIV and HCV co-infected patients

Two separate studies presented today at The International Liver Congress 2016 in Barcelona, Spain have offered alternative conclusions regarding the efficacy of direct-acting antivirals (DAAs) among patients co-infected with HIV and Hepatitis C virus (HCV).

13 Apr 2016

Prime boost approach can increase possibility of combined HCV and HIV vaccination

A combined vaccination against Hepatitis C virus (HCV) and HIV moved a step closer, with the results of a study presented at The International Liver Congress 2016 in Barcelona, Spain today.

13 Apr 2016

Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Radiation is a commonly used therapeutic option to treat liver metastases, with the majority of tumors maintained under control after one year. However, some patients do not respond as well to radiation treatment, and the factors that predict patient outcomes are unclear. Moffitt Cancer Center researchers report that liver metastases have different sensitivities to radiation therapy based on the location of the primary tumor.

13 Apr 2016

New research shows type 2 diabetes as important risk factor for chronic liver disease

People with type 2 diabetes are at greater risk of serious liver disease than those without the condition, new research has shown.

13 Apr 2016

Scientists use FAN1 knockout mice to refine detailed mechanisms involved in damaged DNA repair

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell--sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet over the course of a life moving through this world, our DNA does get damaged, and our cells have a host of complicated repair mechanisms to deal with such injuries.

13 Apr 2016

Mouse-based study shows exercise decreases cancer incidence, slows tumor growth

When you're pounding along an icy pavement or sweating through a gym workout, you try to remind yourself of the many health benefits of exercise. Between gasps, you can say that a healthy, fit lifestyle helps prevents obesity, a worldwide problem of increasing magnitude that has been linked to cardiovascular disease and diabetes.

11 Apr 2016

Traditional Chinese medicinal plant produces compounds that may help to kill human cancers

New research led by Professor Cathie Martin of the John Innes Centre has revealed how a plant used in traditional Chinese medicine produces compounds which may help to treat cancer and liver diseases.

11 Apr 2016

Newcastle scientists develop new type of genetic blood test to diagnose liver scarring

Newcastle scientists and medics have developed a new type of genetic blood test that diagnoses scarring in the liver - even before someone may feel ill.

11 Apr 2016

Study finds how tumour cells grow through scavenging bad cholesterol

Several studies have recognized a link between obesity and cancer. Richard Lehner, professor of Pediatrics and investigator at the University of Alberta's Faculty of Medicine & Dentistry, has taken his research further to understand how tumour cells grow through scavenging very low-density lipoproteins (VLDL) and low-density lipoproteins (LDL), commonly known as the "bad cholesterol", and what mechanisms can be used to reduce the malignant cells' growth.

11 Apr 2016

Vanderbilt's A.S.A.P sees increase in number of patients treated for alpha-gal syndrome

Vanderbilt's Asthma, Sinus and Allergy Program (A.S.A.P) has seen an increase in the number of patients being treated for alpha-gal syndrome, commonly known as the red meat allergy linked to tick bites.

7 Apr 2016

Genetically modified pig hearts can survive for more than 2 years after transplantation into baboons

Could organs explanted from other mammals save human lives someday? A new study shows that genetically modified pig hearts developed by US and Ludwig-Maximilians-Universitaet in Munich researchers can survive for more than up to 2½ years when transplanted into baboons.

7 Apr 2016

Phenotypic personalized medicine can identify a person's optimal drug, dose combinations

For decades, doctors and scientists have predicted that personalized medicine — tailoring drug doses and combinations to people's specific diseases and body chemistry — would be the future of health care.

7 Apr 2016

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Advances in technology allow scientists to measure intricate details about the human body that greatly enhance understanding of health, disease and aging.

7 Apr 2016

Cuts in alcohol taxation could increase alcohol-related deaths in England

Death rates in England fell for six years when alcohol duty was increased, but will now rise as taxes are cut and incomes rise.

7 Apr 2016

SCIEX and QPS Holdings enter collaboration to establish the BioBA solution for bioanalysis of biologics

SCIEX, a global leader in life science analytical technologies, and QPS Holdings, LLC (QPS), a leading global full-service Contract Research Organization (CRO), today announced a collaboration to advance Hybrid LBA –LCMS, a workflow for routine biologics quantification. Under the agreement, QPS Holdings will deploy the SCIEX BioBA Solution, the first end-to-end and most complete solution for bioanalysis of biologics.

6 Apr 2016

3D MRE offers accurate non-invasive method to detect advanced fibrosis

Nonalcoholic fatty liver disease, or NAFLD, comprises a group of liver disorders whose prevalence is widespread and rising. It's estimated that at least one-third of Americans have NAFLD; among obese persons, the figure is 50 percent.

6 Apr 2016

Researchers find prevalence of steatosis in liver transplant recipients

Researchers have characterized the prevalence and risk factors of fatty liver disease in patients who undergo liver transplantation. The findings, which are published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases, could have important implications for safeguarding transplant recipients' health.

6 Apr 2016

Innovative nano-therapy treatment can fight chronic inflammatory disorders, cancer

For an innovative treatment, which allows to selectively direct nanoparticles of iron oxide into cell targets in the blood to fight chronic inflammatory disorders or cancer that was successfully tested in a cell culture and animal models, Dr. Andrea de Vizcaya Ruiz, was awarded with the Innovation Award in Bionanotechnology Cinvestav-Neolpharma 2015.

6 Apr 2016

Inflectra (infliximab-dyyb) approved for multiple indications

The U.S. Food and Drug Administration today approved Inflectra (infliximab-dyyb) for multiple indications. Inflectra is administered by intravenous infusion. This is the second biosimilar approved by the FDA.

6 Apr 2016

Liver News and Research

HCV patients with hepatocellular carcinoma history could re-develop illness during or after taking DAAs

Studies offer alternative conclusions on efficacy of DAAs for HIV and HCV co-infected patients

Prime boost approach can increase possibility of combined HCV and HIV vaccination

Moffitt study reports that liver metastases have different sensitivities to radiation therapy

New research shows type 2 diabetes as important risk factor for chronic liver disease

Scientists use FAN1 knockout mice to refine detailed mechanisms involved in damaged DNA repair

Mouse-based study shows exercise decreases cancer incidence, slows tumor growth

Traditional Chinese medicinal plant produces compounds that may help to kill human cancers

Newcastle scientists develop new type of genetic blood test to diagnose liver scarring

Study finds how tumour cells grow through scavenging bad cholesterol

Vanderbilt's A.S.A.P sees increase in number of patients treated for alpha-gal syndrome

Genetically modified pig hearts can survive for more than 2 years after transplantation into baboons

Phenotypic personalized medicine can identify a person's optimal drug, dose combinations

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Cuts in alcohol taxation could increase alcohol-related deaths in England

SCIEX and QPS Holdings enter collaboration to establish the BioBA solution for bioanalysis of biologics

3D MRE offers accurate non-invasive method to detect advanced fibrosis

Researchers find prevalence of steatosis in liver transplant recipients

Innovative nano-therapy treatment can fight chronic inflammatory disorders, cancer

Inflectra (infliximab-dyyb) approved for multiple indications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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