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EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Oxford spinout EvOx Therapeutics will harness the body’s own precision communications system to deliver drugs to specific parts of the body, with the aim of treating conditions which are currently untreatable including those affecting the brain, as well as autoimmune diseases and cancers.

11 May 2016

Researchers examine role of neural circuit in making decisions

Choosing what shirt to buy, what to order for lunch or whether to go with the hearty red wine or the lighter white all involve assigning values to the options. A small brain structure plays a central role in the many decisions like this we make each day. But it hasn't been clear how a limited number of neurons in this small part of the brain can support an unlimited number of choices.

10 May 2016

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Neuroimaging studies of interconnected brain networks may provide the "missing links" between behavioral and biological models of cognitive vulnerability to depression, according to a research review in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.

10 May 2016

LaVision BioTec to debut latest light sheet microscope at analytica 2016

LaVision BioTec, developers of advanced microscopy solutions for the life sciences, will demonstrate their latest light sheet microscope, the UltraMicroscope II at the forthcoming analytica 2016 meeting in Munich.

9 May 2016

Scientists develop new technology that helps visualize translation of mRNA into proteins

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial findings using this technology that may shed light on neurological diseases as well as cancer were published online today in Science.

9 May 2016

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Michigan State University researchers used an old-fashioned neurobiology technique to explore new avenues for treatments to reverse a late-onset neurodegenerative disease that robs men of the capacity to walk, run, chew and swallow.

9 May 2016

Researchers find way to selectively deliver drugs to placenta without harming fetus

Nearly 10 percent of babies born in the United States are born premature, according to the March of Dimes. The underlying cause of many complications during pregnancy is often a poorly functioning placenta, the organ that nourishes and maintains the fetus.

9 May 2016

Implantable brain device shows promising results in animal study

An implantable brain device that literally melts away at a pre-determined rate minimizes injury to tissue normally associated with standard electrode implantation, according to research led by a team from the Perelman School of Medicine at the University of Pennsylvania.

6 May 2016

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Loss of appetite during illness is a common and potentially debilitating phenomenon--in cancer patients, especially, it can even shorten lifespan.

5 May 2016

Study shows short-term statin treatment does not benefit heart surgery patients

Giving daily doses of statins for a few days before and after heart surgery does not prevent heart muscle damage or the development of atrial fibrillation (AF), according to an international clinical trial led by the University of Oxford and funded by the British Heart Foundation.

5 May 2016

Historical and modern perspectives in management of basilar invagination

Winner of the Vesalius Award Award, Abhidha Harshad Shah, MS, MD, presented her research, Management of Basilar Invagination: A Historical Perspective, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Human brains constantly make statistical computations to estimate confidence

The directions, which came via cell phone, were a little garbled, but as you understood them: "Turn left at the 3rd light and go straight; the restaurant will be on your right side." Ten minutes ago you made the turn. Still no restaurant in sight. How far will you be willing to drive in the same direction?

5 May 2016

New research shows molecular, cellular processes in human embroyo development

Despite significant biomedical advances in recent decades, the very earliest events of human development¬--those that occur during a critical window just after fertilization--have remained an unobservable mystery, until now.

5 May 2016

EPFL neuroscientists find that the brain can filter out cardiac sensations

Our heart is constantly beating yet we normally do not feel it. It turns out that our brain is capable of filtering out the cardiac sensation so that it doesn't interfere with the brain's ability to perceive external sensations. For the first time, researchers from the Center for Neuroprosthetics at EPFL have identified this mechanism. They discovered that a certain region in the brain determines where internal and external sensations interact. Their work appears in the Journal of Neuroscience.

5 May 2016

Researchers monitor ICP and PRx to characterize temporal evolution in severe TBI patients

Winner of the Best International Abstract Award, Hadie Adams, presented his research, Characterizing the Temporal Evolution of ICP and Cerebrovascular Reactivity after Severe Traumatic Brain Injury, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Research provides new insight into cellular composition of IDH1-mutant gliomas

Winner of the Preuss Research Award, Andrew Venteicher, MD, PhD, presented his research, Cellular Architecture of Human IDH1-mutant Gliomas Revealed Using Single-cell RNA Sequencing, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Study analyzes PI, RI of patients who underwent AVM embolization and surgical resection

Winner of the Louise Eisenhardt Traveling Scholarship, Sophia F. Shakur, MD, IFAANS, presented her research, Changes in Pulsatility and Resistance Indices of Cerebral Arteriovenous Malformation Feeder Arteries after Embolization and Surgery, during the 2016 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.

4 May 2016

Researchers investigate incidence of new position-related nerve deficit in spine surgery

Winner of the Sanford J. Larson, MD, PhD, Award, Gurpreet Surinder Gandhoke, MD, presented his research, Incidence of Position Related Neuropraxia in 4,489 Consecutive Patients Undergoing Spine Surgery. Role of SSEP Monitoring? during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

Lund study shows transplanted nerve cells can survive for many years in diseased human brain

In the late 1980s and over the 1990s, researchers at Lund University in Sweden pioneered the transplantation of new nerve cells into the brains of patients with Parkinson's disease. The outcomes proved for the first time that transplanted nerve cells can survive and function in the diseased human brain. Some patients showed marked improvement after the transplantation while others showed moderate or no relief of symptoms.

4 May 2016

Neuroscience News and Research

EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Researchers examine role of neural circuit in making decisions

Neuroimaging studies offer new insights into cognitive vulnerability to depression

LaVision BioTec to debut latest light sheet microscope at analytica 2016

Scientists develop new technology that helps visualize translation of mRNA into proteins

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Researchers find way to selectively deliver drugs to placenta without harming fetus

Implantable brain device shows promising results in animal study

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Study shows short-term statin treatment does not benefit heart surgery patients

Historical and modern perspectives in management of basilar invagination

Human brains constantly make statistical computations to estimate confidence

New research shows molecular, cellular processes in human embroyo development

EPFL neuroscientists find that the brain can filter out cardiac sensations

Researchers monitor ICP and PRx to characterize temporal evolution in severe TBI patients

Research provides new insight into cellular composition of IDH1-mutant gliomas

Study analyzes PI, RI of patients who underwent AVM embolization and surgical resection

Researchers investigate incidence of new position-related nerve deficit in spine surgery

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

Lund study shows transplanted nerve cells can survive for many years in diseased human brain

Event guide: 2nd Neuroscience Innovation Partnering & Licensing Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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