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Researchers share results of MVA-BN-respiratory syncytial virus vaccine human challenge trial

Researchers reported the immunogenicity, efficacy, and safety of the MVA-BN (modified vaccinia Ankara-Bavarian Nordic)-RSV (respiratory syncytial virus) vaccine against RSV-A (RSV subtype A) Memphis 37b strain in a human challenge trial.

7 Dec 2022

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Nearly three years into the pandemic, many of us now carry antibodies against the virus - due to an infection or two, a few doses of mRNA vaccine, or a round of monoclonal-antibody treatment.

6 Dec 2022

Paper-based synthetic biosensor could help easily detect toxin putrescine in beef

The supply chain that brings meat to market worldwide is highly complex and usually very efficient. But when disruptions in one part of the world can result in transportation delays an ocean and a continent away, meat spoilage becomes a very real risk to food producers, vendors and consumers.

6 Dec 2022

Research extends the powerful tool of immunotherapy to autoimmune diseases

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

6 Dec 2022

Gestational diabetes mellitus linked to early particulate matter exposure with high BMI

Researchers assess the impact of high BMI before pregnancy, coupled with exposure to different levels of PM, on the incidence of gestational diabetes.

6 Dec 2022

Colorectal cancer doesn’t wait - DNA methylation tests facilitate earlier treatment

In this interview, Yantao Li and Zhe Wang, Director of Cancer Early Screening Products and the Product Director of Oncology at BGI Genomics, talks to NewsMedical about colorectal cancer (CRC), including why incidences are important and the importance of screening.

From BGI Genomics 6 Dec 2022

Research reveals a novel viral strategy in modulating stress granule formation to promote virus infection

Researchers illustrated a novel strategy likely employed by viruses to promote infection.

6 Dec 2022

NUS scientists develop novel low-cost method of testing for cancers

Scientists from the National University of have discovered a novel low-cost method of testing for cancers.

5 Dec 2022

Eating ultra-processed foods increases risk of cognitive decline

The consumption of ultra-processed foods increases the risk of cognitive decline, particularly among middle-aged adults.

5 Dec 2022

Study explores histopathological, serological, and clinical characteristics of PASC in patients with mild COVID-19

Researchers investigated the clinical, histopathological, imaging, and serological characteristics of post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) in patients with mild COVID-19.

5 Dec 2022

Immunopeptidome characters of human CoV-OC43-infected cells

Researchers explored T-cell epitopes derived from human seasonal coronavirus OC43.

5 Dec 2022

Discovery offers an avenue for development of novel therapies for Chagas disease

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects some 8 million people worldwide. More than a third develop severe heart or digestive problems with a heightened risk of death.

5 Dec 2022

Study provides understanding of SARS-CoV-2 pulmonary infection long-term effects at the microanatomical, cellular, and molecular level

Researchers evaluated compositional and structural pulmonary alterations in PASC tissues.

5 Dec 2022

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.

5 Dec 2022

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers developed an mRNA technology-based vaccine candidate against the monkeypox virus and evaluated its immunogenicity in animal models.

5 Dec 2022

Researchers uncover the host protease CAPN2 as a novel host factor that aids the infection of SARS-CoV-2

Researchers investigated the potential of the CAPN2 molecule as a therapeutic target against SARS-CoV-2.

5 Dec 2022

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Lipid nanoparticle (LNP)-based messenger ribonucleic acid (mRNA) vaccines have recently emerged as a promising strategy for the prevention and treatment of cancers, as well as infectious diseases.

4 Dec 2022

AI could make doctors’ work simpler, faster, and more precise

One in nine women in the developed world will be diagnosed with breast cancer at some point in her life. The prevalence of breast cancer is increasing, an effect caused in part by the modern lifestyle and increased lifespans.

2 Dec 2022

SARS-CoV-2 Omicron infections pose long-COVID risks despite reduced severity

researchers compared the post-coronavirus disease complaints and symptoms in individuals infected with the SARS-CoV-2 Omicron variant with those in individuals with Delta variant infections to understand whether the long-term complaints after Omicron infections are similar to those in infections with other SARS-CoV-2 variants.

2 Dec 2022

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Researchers from the United States developed an affordable, non-invasive, inhalable prophylactic treatment consisting of immunoglobulin (Ig) A fused nanobodies against the SARS-CoV-2 Omicron variant.

2 Dec 2022

Protein C News and Research

Researchers share results of MVA-BN-respiratory syncytial virus vaccine human challenge trial

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Paper-based synthetic biosensor could help easily detect toxin putrescine in beef

Research extends the powerful tool of immunotherapy to autoimmune diseases

Gestational diabetes mellitus linked to early particulate matter exposure with high BMI

Colorectal cancer doesn’t wait - DNA methylation tests facilitate earlier treatment

Research reveals a novel viral strategy in modulating stress granule formation to promote virus infection

NUS scientists develop novel low-cost method of testing for cancers

Eating ultra-processed foods increases risk of cognitive decline

Study explores histopathological, serological, and clinical characteristics of PASC in patients with mild COVID-19

Immunopeptidome characters of human CoV-OC43-infected cells

Discovery offers an avenue for development of novel therapies for Chagas disease

Study provides understanding of SARS-CoV-2 pulmonary infection long-term effects at the microanatomical, cellular, and molecular level

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers uncover the host protease CAPN2 as a novel host factor that aids the infection of SARS-CoV-2

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

AI could make doctors’ work simpler, faster, and more precise

SARS-CoV-2 Omicron infections pose long-COVID risks despite reduced severity

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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