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Researchers discover potential target for cherubism

Cancer researchers studying genetic mutations that cause leukemia have discovered a connection to the rare disease cherubism, an inherited facial bone disorder in children.

9 Dec 2011

MSU researcher uses MRI to unlock how cerebral malaria damages brain

Building on a quarter century of work in Malawi, a Michigan State University researcher is traveling to neighboring Zambia to perform MRI scans on children newly diagnosed with cerebral malaria in hopes of unlocking how it damages the brain.

9 Dec 2011

Genetically identical Salmonella appear in 2 types, each with an infective advantage

An unusual regulatory mechanism that controls the swimmer/non-swimmer option in genetically identical Salmonella also impacts the bacteria's ability to cause infection.

9 Dec 2011

Women with non-melanoma skin cancers more likely to have smoked cigarettes

Women who have non-melanoma skin cancers are more likely to have smoked cigarettes compared to women without skin cancer, said researchers at Moffitt Cancer Center in Tampa, Fla., who published study results in a recent issue of Cancer Causes & Control.

9 Dec 2011

Scientists uncover three new locations for Crohn's Disease genes

Three new locations for Crohn's Disease genes have been uncovered by scientists at UCL using a novel gene mapping approach.

9 Dec 2011

ACEP Emergency Ultrasound Guidelines receive AIUM recognition

In keeping with the American Institute of Ultrasound in Medicine's (AIUM) overarching mission of advancing the safe and effective use of ultrasound in medicine through education, research and development of guidelines, the AIUM recognizes the American College of Emergency Physicians (ACEP) Policy Statement Emergency Ultrasound Guidelines as meeting the qualifications for performing ultrasound in the emergency setting.

9 Dec 2011

Viewpoints: Politics overtakes Plan B; Gingrich's entitlement plans; Cheeseburgers and death

Once again, the politics of birth control have trumped science and sound public policy. On Wednesday, the Obama administration overruled a carefully reasoned decision by the Food and Drug Administration to make the so-called morning-after pill available without prescription to adolescent girls below the age of 17.

9 Dec 2011

Toxins in Danish mushroom are effective against cancer cells

Researchers at the University of Copenhagen have explored the active principles of a Danish mushroom and found that some of the substances it contains are particularly toxic towards cancer cells. The goal is to synthesise and refine substances in the mushroom that may be useful in future drug development.

9 Dec 2011

Galectin Therapeutics to initiate GM-CT-01 Phase 1/2 combination study in advanced MM

Galectin Therapeutics, the Cancer Centre at the Cliniques universitaires Saint-Luc and the Ludwig Institute for Cancer Research (LICR) announced today that they will initiate a Phase 1/2 safety and efficacy trial testing a novel treatment combination in patients with advanced metastatic melanoma.

9 Dec 2011

Working night shifts may raise risk of diabetes: Study

About 26% percent of the American workforce, including health-care workers and sanitation staff, need to work night shifts. Earlier research has shown that regular night shifts may disrupt the circadian rhythm, raising the risk of heart disease, obesity, ulcers and even depression.

8 Dec 2011

Breast cancer risks and management updates

A new report that looks at the environmental factors that affect risk of breast cancer is out. It suggests that women can reduce their risk by avoiding unnecessary medical radiation, forgoing hormone treatments for menopause that combine estrogen and progestin, limiting alcohol intake and minimizing weight gain.

8 Dec 2011

Sebelius overturns FDA on morning after pill access

The Health and Human Services Secretary Kathleen Sebelius this Wednesday has overturned the Food and Drug Administration's plan to remove the age limit on who can buy Teva Pharmaceutical Industries Ltd's Plan B One-Step pill – commonly known as the “morning after pill” without a prescription.

8 Dec 2011

Race, ethnicity, and insurance status influence follow-up care

According to the results of a new study published in the Journal of the American College of Surgeons, African-Americans, Hispanics and uninsured patients use fewer post-hospitalization services after traumatic injury, including home health care, skilled nursing care, and rehabilitation.

8 Dec 2011

Clues to underlying causes of atherosclerosis

By changing the behavior of certain cells within human blood vessels, Cornell University researchers have discovered important clues as to the underlying causes of atherosclerosis - a discovery researchers hope can lead to more targeted drug therapies for the prevention of the disease.

8 Dec 2011

Recommendations to address challenges associated with chronic inflammatory diseases

A dramatic increase in the incidence of chronic inflammatory diseases such as asthma, allergy, and irritable bowel syndrome, has led to concern about how modern lifestyles may trigger physiological defense mechanisms.

8 Dec 2011

Study identifies tertiary treatment as an important source of antibiotic resistant genes

Water discharged into lakes and rivers from municipal sewage treatment plants may contain significant concentrations of the genes that make bacteria antibiotic-resistant. That's the conclusion of a new study on a sewage treatment plant on Lake Superior in the Duluth, Minn., harbor that appears in ACS' journal Environmental Science & Technology.

8 Dec 2011

Study contradicts premise of framing effect on making health decisions

The behavior of consumers who are faced with making decisions about their health is not significantly influenced by the way health messages are worded or framed, according to a large, new study by researchers at the University at Buffalo and other institutions.

8 Dec 2011

Zoledronic acid increases bone mineral density, reduces recurrence in postmenopausal breast cancer

The addition of zoledronic acid to adjuvant endocrine therapy increased bone mineral density and reduced the risk for disease recurrence among postmenopausal women with early hormone receptor-positive breast cancer, according to new data from the ZO-FAST trial.

8 Dec 2011

Considering varying extent to which genes are turned on or off can help develop personalised, predictive medicines

The vast majority of genetic disorders (schizophrenia or breast cancer, for example) have different effects in different people. Moreover, an individual carrying certain mutations can develop a disease, whereas another one with the same mutations may not. This holds true even when comparing two identical twins who have identical genomes. But why does the same mutation have different effects in different individuals?

8 Dec 2011

Federal officials push greater medical use of gene sequencing

Almost a year after researchers in Wisconsin published a groundbreaking paper describing their use of genetic sequencing to diagnose and treat a 4-year-old boy, a national health agency is shifting its focus to put $416 million into making the secrets of our genetic script part of standard medical practice.

8 Dec 2011