Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

Although Zika and dengue are considered different virus "species," they are so closely related that the immune system treats Zika just like another version of dengue, report researchers at La Jolla Institute for Allergy and Immunology.

13 Mar 2017

Evolution of immuno-oncology

Immuno-oncology did not exist four years ago, it's a term coined by Dr. Axel Hoos, Head of the newly defined immuno-oncology department at GSK. He is also Senior Vice President Therapeutic Area (TA) and Head for Oncology R&D. Previously, it was referred to as cancer immunotherapy, but now it is called immuno-oncology (IO).

13 Mar 2017

New biomarkers may help in diagnosis and management of Crohn's disease

The diagnosis, understanding and management of Crohn's disease may have just received a helping hand from a joint ASU Biodesign Institute and Mayo Clinic study aimed at developing a better blood test for the disease.

9 Mar 2017

Mayo Clinic researchers find new experimental drug that shrinks tumors in multiple myeloma patients

Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma. The findings are published in Nature Medicine.

8 Mar 2017

Bruker showcases innovative high-performance systems and high-value analytical solutions at Pittcon 2017

Bruker (NASDAQ: BRKR) is showcasing a selection of innovative high-performance systems and high-value analytical solutions at Pittcon 2017 (www.pittcon.org), with an emphasis on pharma and applied markets, as well as on nano-materials research and microscopy.

From Bruker BioSpin Group 7 Mar 2017

Researchers uncover new genetic clues linked to autoimmune kidney disease

Researchers have uncovered new genetic clues to understanding IgA nephropathy (IgAN), or Berger's disease, an autoimmune kidney disease and a common cause of kidney failure.

6 Mar 2017

Sartorius to Acquire Real-Time Live-Cell Analysis Pioneer and Leader Essen BioScience

Sartorius, a leading partner to the biopharmaceutical industry and laboratories, today signed an agreement to acquire U.S. based Essen BioScience Inc.,

From Sartorius 6 Mar 2017

Notch activity of cells in tumor microenvironment can influence cancer metastases, study shows

Blood vessels play a critical role in the growth and spread of cancer. The cells lining the inner wall of blood vessels (endothelial cells) and cancer cells are in close contact to each other and mutually influence each other.

3 Mar 2017

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery.

3 Mar 2017

Research provides insights on antibody-mediated rejection in kidney transplant patients

New research provides insights on transplant recipients' antibody responses against donor kidneys and how the timing of those responses can have important implications. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology.

3 Mar 2017

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Using antibodies to treat disease has been one of the great success stories of early 21st-century medicine. Already five of the ten top-selling pharmaceuticals in the United States are antibody products. But antibodies are large, complex proteins that can be expensive to manufacture.

2 Mar 2017

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

A Japanese research group has discovered that a newly-identified autoimmune endocrine disease that leads to hypopituitarism is caused by thymomas (a type of tumor originating from the thymic gland).

2 Mar 2017

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Between 3 and 5% of the population suffer from a form of inflammatory rheumatism. It affects approximately 250,000 - 400,000 people in Austria.

2 Mar 2017

Researchers develop testing program to study potency of vaccines for neglected tropical diseases

A new generation of vaccines for neglected tropical diseases is moving into clinical trials, and understanding the long-term stability and effectiveness of these vaccines over periods of storage is key to their success.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

New anti-cocaine monoclonal antibody moves forward towards clinical studies in humans

A University of Cincinnati researcher who has developed an immunotherapy to help reverse cocaine addiction that's been successful in animal models says he hopes to have it in clinical trials in human volunteers within a year.

28 Feb 2017

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets. Study results were published in the journal Molecular Therapy.

24 Feb 2017

Scientists propose potential new treatment for Gaucher disease

Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than current therapies.

23 Feb 2017

Precise inactivation of neurotransmitter receptors using CALI technique erases fear memory in mice

The delivery of chemical messenger (neurotransmitter) receptors to the junctions between nerve cells (synapses) is crucial to cognitive processes such as memory.

23 Feb 2017

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

If you've ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens.

22 Feb 2017

Antibody News and Research

Further Reading

Pre-existing immunity to dengue virus modulates T cell response to Zika infection

Evolution of immuno-oncology

New biomarkers may help in diagnosis and management of Crohn's disease

Mayo Clinic researchers find new experimental drug that shrinks tumors in multiple myeloma patients

Bruker showcases innovative high-performance systems and high-value analytical solutions at Pittcon 2017

Researchers uncover new genetic clues linked to autoimmune kidney disease

Sartorius to Acquire Real-Time Live-Cell Analysis Pioneer and Leader Essen BioScience

Notch activity of cells in tumor microenvironment can influence cancer metastases, study shows

NovAliX's new laboratory to use cryo-TEM for facilitating small molecule and biologic drug discovery

Research provides insights on antibody-mediated rejection in kidney transplant patients

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Researchers develop testing program to study potency of vaccines for neglected tropical diseases

Using Spherical Nucleic Acids to Track and Treat Disease

New anti-cocaine monoclonal antibody moves forward towards clinical studies in humans

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Scientists propose potential new treatment for Gaucher disease

Precise inactivation of neurotransmitter receptors using CALI technique erases fear memory in mice

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

How to make hybridoma-based antibody discovery more efficient eBook

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