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Charles River Laboratories Launches Off-the-Shelf Lentiviral Vector Packaging Plasmids

Charles River Laboratories International, Inc. (NYSE: CRL) today announced the launch of its off-the-shelf lentiviral vector (LVV) packaging plasmids, providing a streamlined solution to the challenges associated with plasmid sourcing in cell and gene therapies.

From Charles Rivers Laboratories Cell and Gene Therapy 13 Jun 2023

Repeat intraocular corticosteroid injections improve vision in people with persistent or recurrent uveitic macular edema

Repeat treatment with corticosteroid injections improved vision in people with persistent or recurrent uveitis-related macular edema better than two other therapies, according to results from a clinical trial funded by the National Eye Institute.

13 Jun 2023

Study provides a new and promising strategy for future cancer immunotherapies

CD8+ T cells, a vital component of the immune system that provides immunity against cancer, have been the focal point of anti-cancer therapies.

13 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Study reveals alarming pediatric antibiotic prescribing practices in Madagascar, Senegal, and Cambodia

In a recent article published in the journal PLOS Medicine, researchers performed a prospective, longitudinal study to estimate the proportion of outpatient consultations resulting in inappropriate antibiotic prescriptions in young children in three low- and middle-income countries (LMICs), Madagascar, Senegal, and Cambodia.

13 Jun 2023

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

A decade after UC San Francisco scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in repairing the brain, making it possible to also assess future therapies for the devastating disorder.

13 Jun 2023

Antiretroviral treatment efficiently suppresses penile HIV replication

Of the 38 million people worldwide living with HIV, approximately 700,000 are newly infected men, primarily via sexual transmission.

12 Jun 2023

Manipulating white blood cells to eliminate solid tumors

By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors.

12 Jun 2023

Study suggests the role of histamine-releasing factor in severe asthma and RV-induced asthma exacerbation

Asthma is more dangerous than many people realize. An estimated 10 Americans die everyday from asthma, and the disease leads to around 439,000 hospitalizations and 1.3 million emergency room trips each year.

12 Jun 2023

Researchers test a new way to deliver mental health therapy to people with addiction, aggressive behavior

Researchers from five colleges at Rochester Institute of Technology are testing a new way to deliver mental health therapy to people struggling with alcohol/drug addiction and aggressive behavior.

12 Jun 2023

Researchers identify a potential breakthrough in glioblastoma treatment

In a recently published manuscript, Howard Colman, MD, PhD, Jon M. Huntsman Presidential Professor of Neuro-Oncology and co-leader of the Neurologic Cancers Disease Center and the Experimental Therapeutics CCSG program at Huntsman Cancer Institute, identified a potential breakthrough in glioblastoma treatment.

12 Jun 2023

Chronic exposure to lead, cadmium and arsenic associated with increased risk of cardiovascular disease

Chronic exposure to low levels of lead, cadmium and arsenic through commonly used household items, air, water, soil and food is associated with an increased risk of cardiovascular disease, according to a new American Heart Association scientific statement published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

12 Jun 2023

Study provides a possible treatment option for prostate cancer resistant to hormone therapy

Prostate cancer is the most-commonly diagnosed malignancy and the second leading cause of cancer death among men in the United States.

12 Jun 2023

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

The aim of immunotherapy strategies is to use cells in the patient's own immune system to destroy tumor cells. CAR T cell therapy is an immunotherapy that is effective in treating blood cancer.

12 Jun 2023

What does a chatbot know about eating disorders? Users of a help line are about to find out

For more than 20 years, the National Eating Disorders Association has operated a phone line and online platform for people seeking help for anorexia, bulimia, and other eating disorders. Last year, nearly 70,000 individuals used the help line.

12 Jun 2023

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Review discusses the increasing importance of two-dimensional nanomaterials like graphene in neuroscience, highlighting their potential in nerve repair, creating brain-mimicking synaptic devices, and treating neurological disorders. It also considers the challenges and future prospects of these materials in this complex field.

11 Jun 2023

UVA discovery advances efforts to prevent and better treat multiple sclerosis

University of Virginia School of Medicine scientists have discovered a key determinant of our risk for multiple sclerosis, advancing efforts to prevent and better treat the disease.

10 Jun 2023

PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia

Humanigen, Inc.today extended previously reported results by presenting additional, statistically significant hematologic improvements and reductions in inflammatory markers from lenzilumab, its investigational drug, in a Phase 2/3 trial of treatment-naïve participants with chronic myelomonocytic leukemia and RAS-pathway mutations.

9 Jun 2023

How does your Skin Change during Menopause?

Menopause marks the end of a woman’s reproductive years.

9 Jun 2023

Can artificial intelligence provide evidence-based responses to public health questions?

Researchers assessed artificial intelligence (AI)-generated responses to health-related inquiries.

9 Jun 2023

Therapy News and Research

Charles River Laboratories Launches Off-the-Shelf Lentiviral Vector Packaging Plasmids

Repeat intraocular corticosteroid injections improve vision in people with persistent or recurrent uveitic macular edema

Study provides a new and promising strategy for future cancer immunotherapies

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Study reveals alarming pediatric antibiotic prescribing practices in Madagascar, Senegal, and Cambodia

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

Antiretroviral treatment efficiently suppresses penile HIV replication

Manipulating white blood cells to eliminate solid tumors

Study suggests the role of histamine-releasing factor in severe asthma and RV-induced asthma exacerbation

Researchers test a new way to deliver mental health therapy to people with addiction, aggressive behavior

Researchers identify a potential breakthrough in glioblastoma treatment

Chronic exposure to lead, cadmium and arsenic associated with increased risk of cardiovascular disease

Study provides a possible treatment option for prostate cancer resistant to hormone therapy

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

What does a chatbot know about eating disorders? Users of a help line are about to find out

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

UVA discovery advances efforts to prevent and better treat multiple sclerosis

PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia

How does your Skin Change during Menopause?

Can artificial intelligence provide evidence-based responses to public health questions?

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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