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Researchers reveal immune machinery that goes awry to trigger neutrophilic dermatosis

A research team led by St. Jude Children's Research Hospital immunologists has revealed a previously unknown immune machinery that goes awry to trigger the inflammatory disease neutrophilic dermatosis.

18 Apr 2017

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Medical University of South Carolina investigators report that long-term expansion protocols for adoptive cancer immunotherapy do not compromise Th17 cells' effectiveness against large tumors, in the March 9, 2017 issue of JCI Insight.

17 Apr 2017

Combination of anti-angiogenic and immune-stimulating therapies can lead to effective cancer treatments

Scientists from VIB and KU Leuven, together with colleagues from the University of California and the Swiss Institute for Experimental Cancer Research have demonstrated that, anti-angiogenic therapy can improve immune boosting treatments.

13 Apr 2017

Microparticles show potential to deliver DNA-based vaccines and gene therapies in pill form

A microscopic corn-and-shrimp cocktail could eventually make DNA-based vaccinations and cancer-treating gene therapies an easier pill to swallow, according to new research from the University of Nebraska-Lincoln.

12 Apr 2017

Infection with reovirus could be key initiating event for developing celiac disease, study suggests

Infection with reovirus, a common but otherwise harmless virus, can trigger the immune system response to gluten that leads to celiac disease, according to new research from the University of Chicago and the University of Pittsburgh School of Medicine.

6 Apr 2017

Pet exposure may lower risks of allergy and obesity in children

If you need a reason to become a dog lover, how about their ability to help protect kids from allergies and obesity? A new University of Alberta study showed that babies from families with pets--70 per cent of which were dogs--showed higher levels of two types of microbes associated with lower risks of allergic disease and obesity.

6 Apr 2017

Probiotics may help treat yeast infections, bowel problems in men with schizophrenia

In a small pilot study of men with schizophrenia, researchers at Johns Hopkins Medicine and Sheppard Pratt Health System say they have evidence that adding probiotics -- microorganisms, such as bacteria found in yogurts -- to the patients' diets may help treat yeast infections and ease bowel problems.

5 Apr 2017

Hebrew University announces launch of new Center for conducting research on cannabinoids

The Hebrew University of Jerusalem has announced the launch of a Multidisciplinary Center on Cannabinoid Research.

5 Apr 2017

Zika virus may pose increased risk to people previously infected with dengue and West Nile, study finds

As the Zika virus continues to spread rapidly across the globe, it might pose a particular risk to people previously infected with two related viruses, dengue and West Nile, researchers at the Icahn School of Medicine at Mount Sinai have found.

5 Apr 2017

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

By engineering an on/off switch into a weakened form of HIV, University of Nebraska-Lincoln researchers have enhanced the safety and effectiveness of a potential vaccine for the virus that has killed approximately 35 million people during the past 35 years.

30 Mar 2017

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, will highlight a variety of basic research and population studies at the annual meeting of the American Association for Cancer Research at the Walter E. Washington Convention Center in Washington, D.C., April 1 to 5.

28 Mar 2017

Scientists reveal novel drug delivery approach to fight swine flu at gene level

Scientists from Tomsk Polytechnic University together with their colleagues from St. Petersburg and London have elaborated a new approach to deliver anti-viral RNAi to target cells against H1N1 influenza virus infection.

28 Mar 2017

Scientists develop humanized mouse model for analyzing functions of NK cells in vivo

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT, have successfully developed a humanized mouse model showing that so-called NK cells that directly attacking tumors, can survive and maintain function in vivo.

28 Mar 2017

Research findings offer potential explanation for opioid-induced itching

Opioids have long been an important tool in the world of pain management, but the side effects of these drugs - from addiction and respiratory failure to severe itching and dizziness, can be overwhelming.

27 Mar 2017

New research reveals surprising culprit involved in self-destruction of axons

In many neurodegenerative conditions — Parkinson's disease, amyotrophic lateral sclerosis (ALS) and peripheral neuropathy among them — an early defect is the loss of axons, the wiring of the nervous system.

24 Mar 2017

Study links gastrointestinal disturbances of GWI with changes in intestinal microbiota

A new study from the University of South Carolina has found a gastrointestinal link that could help explain many of the health issues facing those with Gulf War Illness (GWI) as well as opening new pathways to treatment options that may improve both gastrointestinal and neurological symptoms associated with the disorder.

23 Mar 2017

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Building on earlier work in designing chimeric human-simian immunodeficiency viruses (SHIVs) that serve as a model of HIV infection of humans, George M. Shaw, MD, PhD, a professor of Hematology/Oncology and Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has received $16.3 million over five years from the National Institute of Allergy and Infectious Diseases to develop a long-sought-after HIV vaccine.

22 Mar 2017

Review of research on wild primates underscores importance of super-spreaders in disease transmission

An extensive review of research on wild primate social networks and parasites underscores the importance of super-spreaders, or central individuals that play an outsized role in transmission of a pathogen.

21 Mar 2017

Immune cells could be new target to treat type 2 diabetes, hypertension in overweight people

Immune cells which are reduced in number by obesity could be a new target to treat diseases such as type 2 diabetes and hypertension that affect overweight people, according to a collaborative study between The University of Manchester, Lund University and the University of Salford.

From The University of Manchester 17 Mar 2017

immunity News and Research

Researchers reveal immune machinery that goes awry to trigger neutrophilic dermatosis

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Combination of anti-angiogenic and immune-stimulating therapies can lead to effective cancer treatments

Microparticles show potential to deliver DNA-based vaccines and gene therapies in pill form

Infection with reovirus could be key initiating event for developing celiac disease, study suggests

Pet exposure may lower risks of allergy and obesity in children

Probiotics may help treat yeast infections, bowel problems in men with schizophrenia

Hebrew University announces launch of new Center for conducting research on cannabinoids

Zika virus may pose increased risk to people previously infected with dengue and West Nile, study finds

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

Scientists reveal novel drug delivery approach to fight swine flu at gene level

Scientists develop humanized mouse model for analyzing functions of NK cells in vivo

Research findings offer potential explanation for opioid-induced itching

New research reveals surprising culprit involved in self-destruction of axons

Study links gastrointestinal disturbances of GWI with changes in intestinal microbiota

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Review of research on wild primates underscores importance of super-spreaders in disease transmission

Immune cells could be new target to treat type 2 diabetes, hypertension in overweight people

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