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Antidepressant doxepin eases pain associated with oral mucositis

An oral rinse of the antidepressant doxepin significantly eased pain associated with oral mucositis in patients receiving radiation therapy for cancers of the head and neck, a study led by Mayo Clinic found. The findings were presented at the American Society for Radiation Oncology annual meeting in Boston.

29 Oct 2012

Researchers learn how E2-79 molecule destroys complexes that induce allergic responses

Researchers have learned how a man-made molecule destroys complexes that induce allergic responses - a discovery that could lead to the development of highly potent, rapidly acting interventions for a host of acute allergic reactions.

29 Oct 2012

GTx to continue enobosarm Phase III trials for muscle wasting in patients with NSCLC

GTx, Inc. today announced that a per protocol interim safety review on Friday, October 26, 2012, by an independent Data Safety Monitoring Board (DSMB) recommended that GTx continue clinical development as planned with its two pivotal Phase III trials of enobosarm (GTx-024) for the prevention and treatment of muscle wasting in patients with non-small cell lung cancer.

29 Oct 2012

High worldwide drug-resistant TB figures are “worrying

The prevalence of resistance to second-line therapy among individuals with multi-drug resistant tuberculosis is high, show the results of a study conducted using data from eight countries worldwide.

26 Oct 2012

New treatments show promise for people with food allergies

New treatments are offering the prospect of eating without fear for the 15 million people in the United States with food allergies, according to the cover story in the current issue of Chemical & Engineering News.

26 Oct 2012

Durata completes target enrollment in dalbavancin Phase 3 trial for ABSSSI

Durata Therapeutics today announced that it has completed its target enrollment for DISCOVER 2 ("Dalbavancin for Infections of the Skin COmpared to Vancomycin at an Early Response"), the second global, Phase 3 clinical trial of Durata's lead product candidate, dalbavancin, under investigation for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive bacteria.

26 Oct 2012

New method of oral vaccination could help boost immunity to TB, influenza and C. difficile

Scientists at Royal Holloway, University of London have developed a pioneering new method of oral vaccination which could help boost immunity to TB and influenza, as well as prevent C. difficile for which there is currently no vaccine.

25 Oct 2012

Rapid and point-of-care tests accurate, convenient for hepatitis C screening

Rapid and point-of-care screening tests for hepatitis C have a high accuracy and quick turnaround time, suggest results of a systematic review and meta-analysis.

24 Oct 2012

New biomarker measures aggressiveness of primary prostate tumors

Research out of Roswell Park Cancer Institute (RPCI) supports the adoption of a new biomarker to measure the aggressiveness of primary prostate tumors.

24 Oct 2012

Bayer announces data from riociguat Phase III trial on CTEPH

Bayer HealthCare today announced data from the Phase III CHEST-1 trial evaluating its investigational drug riociguat in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) or with persistent or recurrent pulmonary hypertension (PH) after surgery.

24 Oct 2012

Bisphosphonates increase risk for bone disease after tooth extraction

The risk for developing osteonecrosis of the jaw after a tooth extraction is significantly higher among patients who receive bisphosphonates than those who do not, suggest study findings.

23 Oct 2012

Case reports highlight importance of vitamin and mineral supplementation after bariatric surgery

Non-compliance with vitamin and mineral supplementation protocols after bariatric surgery could lead to nutritional deficiencies and related health complications, such as heart damage, according to two separate case reports unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas.

23 Oct 2012

Advances in endoscopic technologies and techniques to be highlighted at ACG annual meeting

Advances in endoscopic technologies and techniques will be highlighted in clinical research presented at the 77th Annual Scientific Meeting of the American College of Gastroenterology in Las Vegas, NV.

23 Oct 2012

Sickle cell disease treatments: An interview with Dr Niihara, CEO of Emmaus Medical

Sickle cell disease is a devastating hereditary condition that affects millions of people, particularly those in West and Central Africa as well as people of African descent in the United States, Europe and South America.

23 Oct 2012

C. diff infections on the rise among children, elderly

Clostridium difficile infections are becoming more common and more severe in hospitalized children and the elderly, in large part due to greater use of antibiotics, Mayo Clinic researchers report in studies being presented at the American College of Gastroenterology annual meeting.

23 Oct 2012

Pfizer announces intention to acquire NextWave

Pfizer Inc. today announced its intention to acquire NextWave Pharmaceuticals, a privately held, specialty pharmaceutical company focused on the development and commercialization of unique products for the treatment of attention deficit/hyperactivity disorder (ADHD) and related central nervous system (CNS) disorders.

23 Oct 2012

PAC program improves children’s dental care, may serve as invaluable tool for dental students

A partnership between a New York City dental school and a local foster care agency has provided consistent dental care to more than 650 children, and may serve as a model for other dental school program curriculums. The success of Partners Against Caries (PAC), both for the participating foster children and dental school students, was outlined Oct. 21 at the American Academy of Pediatrics (AAP) National Conference and Exhibition in New Orleans.

22 Oct 2012

Bayer announces data from riociguat Phase III pulmonary arterial hypertension trial

Bayer HealthCare today announced data from the Phase III PATENT-1 pulmonary arterial hypertension (PAH) trial evaluating its investigational drug riociguat in both treatment-naive patients and those pre-treated with an endothelin receptor antagonist or an oral, inhaled or subcutaneous prostanoid.

22 Oct 2012

Drospirenone-containing birth control pills associated with increased risk of blood clots

A U.S. Food and Drug Administration-funded study led by the Kaiser Permanente Northern California Division of Research found an increased risk of arterial thrombotic events (ATE) and venous thromboembolic events (VTE) - commonly referred to as blockage of arteries and blood clots, respectively - associated with drospirenone-containing birth control pills compared to four low-dose estrogen combined hormonal contraceptives.

20 Oct 2012

Breast-feeding associated with reduced risk of ER/PR-negative breast cancer

Breast-feeding reduces the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to a study conducted at Columbia University's Mailman School of Public Health.

19 Oct 2012

Oral News and Research

Antidepressant doxepin eases pain associated with oral mucositis

Researchers learn how E2-79 molecule destroys complexes that induce allergic responses

GTx to continue enobosarm Phase III trials for muscle wasting in patients with NSCLC

High worldwide drug-resistant TB figures are “worrying

New treatments show promise for people with food allergies

Durata completes target enrollment in dalbavancin Phase 3 trial for ABSSSI

New method of oral vaccination could help boost immunity to TB, influenza and C. difficile

Rapid and point-of-care tests accurate, convenient for hepatitis C screening

New biomarker measures aggressiveness of primary prostate tumors

Bayer announces data from riociguat Phase III trial on CTEPH

Bisphosphonates increase risk for bone disease after tooth extraction

Case reports highlight importance of vitamin and mineral supplementation after bariatric surgery

Advances in endoscopic technologies and techniques to be highlighted at ACG annual meeting

Sickle cell disease treatments: An interview with Dr Niihara, CEO of Emmaus Medical

C. diff infections on the rise among children, elderly

Pfizer announces intention to acquire NextWave

PAC program improves children’s dental care, may serve as invaluable tool for dental students

Bayer announces data from riociguat Phase III pulmonary arterial hypertension trial

Drospirenone-containing birth control pills associated with increased risk of blood clots

Breast-feeding associated with reduced risk of ER/PR-negative breast cancer

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