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EKF Molecular Diagnostics to present at AMP annual meeting

EKF, announces that senior executives from EKF Molecular Diagnostics including CEO, Andrew Webb, will be present at the Association for Molecular Pathology.

From EKF Diagnostics 6 Nov 2014

OGT workshop to focus on using latest genomic technologies for accelerating cancer research

Oxford Gene Technology, The Molecular Genetics Company, will present a workshop titled ‘An Integrated Genomic Approach to Tumor Profiling’ at the Association for Molecular Pathology annual meeting on the 12-15th November at National Harbor, MD.

From Oxford Gene Technology 6 Nov 2014

Researchers develop mouse model that reproduces most typical features of Noonan syndrome

Noonan syndrome is a rare disease that is characterised by a set of pathologies, including heart, facial and skeletal alterations, pulmonary stenosis, short stature, and a greater incidence of haematological problems (mainly juvenile myeloid leukaemia, or childhood leukaemia).

6 Nov 2014

UCLA study: Asthma harms more than just the lungs, may be more harmful than previously thought

Asthma may be more harmful than was previously thought, according to UCLA researchers who found that genetic damage is present in circulating, or peripheral, blood. Doctors previously thought that the genetic damage it caused was limited to the lungs.

5 Nov 2014

NSAIDs protect against colorectal cancer by inducing cell suicide pathways in intestinal stem cells

Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) protect against the development of colorectal cancer by inducing cell suicide pathways in intestinal stem cells that carry a certain mutated and dysfunctional gene, according to a new study led by researchers at the University of Pittsburgh Cancer Institute and the School of Medicine.

4 Nov 2014

Astellas, Dana-Farber to develop K-Ras inhibitors for treatment of lung, pancreatic cancers

Dana-Farber Cancer Institute (Dana-Farber) and Astellas Pharma Inc. today announced a three-year collaboration to research and develop small molecule inhibitors of oncogenic K-Ras for the treatment of cancer, including lung cancer.

4 Nov 2014

Scientists obtain first structure of the immature form of HIV

Scientists at the European Molecular Biology Laboratory in Heidelberg, Germany and collaborators from Heidelberg University, in the joint Molecular Medicine Partnership Unit, have obtained the first structure of the immature form of HIV at a high enough resolution to pinpoint exactly where each building block sits in the virus.

4 Nov 2014

Broad Institute, UC Berkeley and UCSC receive NCI Cancer Genomics Cloud Pilot contract

A team from the Broad Institute, the University of California, Berkeley, and the University of California, Santa Cruz, was awarded one of three National Cancer Institute Cancer Genomics Cloud Pilot contracts with the goal of building a system that will enable large-scale analysis of The Cancer Genome Atlas and other datasets by co-locating the data and the required computing resources in one cloud environment.

31 Oct 2014

University of Adelaide-led project develops new test to eradicate H5N1 bird flu

A University of Adelaide-led project has developed a new test that can distinguish between birds that have been vaccinated against the H5N1 strain of avian influenza virus or "bird flu" with those that have been naturally infected.

31 Oct 2014

Scientists develop new system to treat a host of genetic conditions

As potential next-generation therapeutics and research tools, few life sciences technologies hold more promise than genome-editing proteins – molecules that can be programmed to alter specific genes in order to treat or even cure genetic diseases.

31 Oct 2014

Two major studies newly implicate dozens of genes in autism

Two major genetic studies of autism, led in part by UC San Francisco scientists and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms that govern whether, when, and how genes are activated overall.

31 Oct 2014

Molecular profiling reveals potential therapeutic targets for lung cancer

Analysis of 607 small cell lung cancer (SCLC) lung tumors and neuroendocrine tumors (NET) identified common molecular markers among both groups that could reveal new therapeutic targets for patients with similar types of lung cancer, according to research presented today at the 2014 Chicago Multidisciplinary Symposium in Thoracic Oncology.

31 Oct 2014

Moffitt researcher uncovers new approach to treat cancer

The scientific community has made significant strides in recent years in identifying important genetic contributors to malignancy and developing therapeutic agents that target altered genes and proteins. A recent approach to treat cancer called synthetic lethality takes advantage of genetic alterations in cancer cells that make them more susceptible to certain drugs.

31 Oct 2014

Aging astrocytes lose ability to protect motor neurons, reveal Cedars-Sinai ALS researchers

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells – motor neurons – in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of muscles throughout the body. Patients typically survive only three to five years after diagnosis.

31 Oct 2014

Changes in cell metabolism slow growth of colorectal cancer

Cancer is an unwanted experiment in progress. As the disease advances, tumor cells accumulate mutations, eventually arriving at ones that give them the insidious power to grow uncontrollably and spread. Distinguishing drivers of cancer from benign mutations open opportunities for developing targeted cancer therapies.

30 Oct 2014

Researchers discover link between seizures and migraines

Seizures and migraines have always been considered separate physiological events in the brain, but now a team of engineers and neuroscientists looking at the brain from a physics viewpoint discovered a link between these and related phenomena.

30 Oct 2014

Growth hormone worthwhile treatment in hypochondroplasia

Researchers report that recombinant human growth hormone can improve growth in children with hypochondroplasia.

30 Oct 2014

Study on papillary thyroid carcinoma to be presented at 84th Annual Meeting of the ATA

The prevalence of papillary thyroid carcinoma (PTC), the most common type of thyroid cancer, is increasing rapidly. New research to determine the impact of radioactive iodine (RAI) therapy on survival in PTC, describing a novel blood test able to detect circulating BRAFV600E-positive tumor DNA, and identifying a long non-coding RNA specifically associated with the thyroid that is down-regulated in PTC compared to normal thyroid tissue in patient-derived clinical specimens and cell cultures will be featured in oral presentations delivered at the 84th Annual Meeting of the American Thyroid Association, October 29-November 2, 2014, in Coronado, California.

30 Oct 2014

BloodCenter of Wisconsin announces availability of cancer mutation HemeOnc Panel

BloodCenter of Wisconsin's Diagnostic Laboratories today announced the availability of a comprehensive cancer mutation HemeOnc Panel using next generation sequencing (NGS) technology. The NGS panel developed by BloodCenter of Wisconsin is designed to detect variants in 30 genes that are either prognostic or diagnostic for 10 different myeloid hematologic malignancies.

30 Oct 2014

New research findings on Graves' disease to be highlighted at ATA meeting

A unique mouse model of Graves' disease, an autoimmune disorder that causes hyperthyroidism, and new research findings that may help improve the treatment of Graves' disease will be highlighted in oral and poster presentations at the 84th Annual Meeting of the American Thyroid Association, October 29-November 2, 2014, in Coronado, California.

30 Oct 2014

Mutation News and Research

EKF Molecular Diagnostics to present at AMP annual meeting

OGT workshop to focus on using latest genomic technologies for accelerating cancer research

Researchers develop mouse model that reproduces most typical features of Noonan syndrome

UCLA study: Asthma harms more than just the lungs, may be more harmful than previously thought

NSAIDs protect against colorectal cancer by inducing cell suicide pathways in intestinal stem cells

Astellas, Dana-Farber to develop K-Ras inhibitors for treatment of lung, pancreatic cancers

Scientists obtain first structure of the immature form of HIV

Broad Institute, UC Berkeley and UCSC receive NCI Cancer Genomics Cloud Pilot contract

University of Adelaide-led project develops new test to eradicate H5N1 bird flu

Scientists develop new system to treat a host of genetic conditions

Two major studies newly implicate dozens of genes in autism

Molecular profiling reveals potential therapeutic targets for lung cancer

Moffitt researcher uncovers new approach to treat cancer

Aging astrocytes lose ability to protect motor neurons, reveal Cedars-Sinai ALS researchers

Changes in cell metabolism slow growth of colorectal cancer

Researchers discover link between seizures and migraines

Growth hormone worthwhile treatment in hypochondroplasia

Study on papillary thyroid carcinoma to be presented at 84th Annual Meeting of the ATA

BloodCenter of Wisconsin announces availability of cancer mutation HemeOnc Panel

New research findings on Graves' disease to be highlighted at ATA meeting

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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